Viral Interference and Interferon

Viral Interference and Interferon
Author: R. D. Andrews
Publisher: Elsevier
Total Pages: 101
Release: 2013-10-22
Genre: Science
ISBN: 1483192768

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Viral Interference and Interferon details the developments in the control of virus infections by natural means. The book is comprised of eight chapters that discuss various aspects of interferon. The text first introduces the main concepts of the subject matter. The succeeding chapter discusses various concerns about interferon, including the production, nature, mechanisms, and mode of actions. The book also covers interferon in humans and animals, and its significance. The text will be of great use to students of microbiology, virology, genetics, and immunology.

Viruses and Interferon

Viruses and Interferon
Author: Karen Mossman
Publisher: Caister Academic Press Limited
Total Pages: 0
Release: 2011
Genre: Science
ISBN: 9781904455813

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Interferons (IFNs) play pivotal roles in shaping the immune responses in mammals and are particularly important for the control of viral infections and cell growth, and immune regulation. These proteins rapidly induce an 'anti-viral state' in cells that surround infected cells. In order to survive, viruses have evolved multiple strategies to evade the anti-viral effects of IFNs. Elucidating the molecular and cellular biology of the virus-interferon interaction is key to understanding issues such as viral pathogenesis, latency, and the development of novel antivirals. In this book, a panel of international experts reviews the current hot-topics, producing a timely overview of this exciting field. The book opens with a chapter that comprehensively reviews the antiviral effects of extracellular double-stranded RNA, the 'viral toxin'. This is followed by chapters that review the properties of type I and type III interferons, and the role of interferon-stimulated genes. The next five chapters are devoted to understanding the diverse strategies used by clinically relevant human viruses to subvert host interferon responses. The closing chapter provides an interesting overview of the clinical application of interferon as antiviral and anticancer agents. Essential reading for every scientist involved in interferon or antiviral research and a recommended text for all virology laboratories.

Endocrine Biomarkers

Endocrine Biomarkers
Author: Hossein Sadrzadeh
Publisher: Elsevier
Total Pages: 478
Release: 2017-09-25
Genre: Science
ISBN: 0128034181

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Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests. Focuses on the traditional, current, and emerging clinical chemistry tests for endocrine and bone diseases, along with their application in individual clinical management Presents a brief discussion of each disorder and its respective interrelationships, along with laboratory methodologies that can be used to aid in evaluation of disorders Reviews common approaches to the measurement of the relevant hormones, with a special focus on measures that require a structured clinical testing scenario Reviews novel chemistry tests as potential means of future diagnostic tests Provides an overview of the current methodology and controversies in the concept of target lipid levels, paying particular attention to the role of clinical chemistry in helping to implement population health targets

Viral Interference

Viral Interference
Author: BioSciences Information Service of Biological Abstracts
Publisher:
Total Pages: 57
Release: 1968
Genre: Interferon
ISBN:

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Antiviral Drugs and Interferon: The Molecular Basis of Their Activity

Antiviral Drugs and Interferon: The Molecular Basis of Their Activity
Author: Yechiel Becker
Publisher: Springer Science & Business Media
Total Pages: 452
Release: 2012-12-06
Genre: Medical
ISBN: 1461338042

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Research on antiviral drugs and their mode of action in infected cells. in animals and in man. has led to a better understanding of the molecular pro cesses involved in virus replication. Screeninq of large numbers of natural and semisynthetic compounds resulted in the characterization of certain sub stances that had a limited efficiency as antiviral druqs. A few chemically synthesized compounds were also found to be effective as antiviral agents in the chemotherapy of human virus diseases. A major difficulty in the develop ment of effective antiviral agents has been the lack of selectivity. and toxicity for uninfected cells. of drugs that effectively inhibited virus replication in vitro. Further understanding of the molecular processes of virus replication in infected cells has resulted in the development of new antivirals directed at virus-coded enzymes or proteins. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs. The present book deals with a number of antiviral drugs effective against herpes simplex viruses and provides some insight into the molecular aspects of virus replication. It also throws light on the new approaches to the development of antiviral drugs. The molecular basis of the antiviral activity of new and known drugs and their possible use in chemotherapy of viral disease are presented in this book.

Virus Interference

Virus Interference
Author: Alick Isaacs
Publisher:
Total Pages: 6
Release: 1957
Genre: Avian influenza
ISBN:

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Interferon

Interferon
Author: J. Vilček
Publisher:
Total Pages: 156
Release: 1969
Genre: Medical
ISBN:

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This monograph is an atttempt to present a balanced up-to-date account of the various aspects of the synthesis and action of interferon, ito serve as a general reference work. There is greater emphasis on recent studies as well as some controversial/speculative material.

SARS, MERS and other Viral Lung Infections

SARS, MERS and other Viral Lung Infections
Author: David S. Hui
Publisher: European Respiratory Society
Total Pages: 148
Release: 2016-06-01
Genre: Medical
ISBN: 1849840709

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Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.