This Transportation Research Record contains 28 papers dealing with statistical methods in highway safety research; highway safety data, analysis, and evaluation; occupant protection; and systematic reviews and meta-analysis. The papers address such topics as risk and crash prediction models, crashes on freeways and at signalized intersections, multivehicle crash prediction, speed and safety, red light running crashes, freeway lane closures, ramp design, accident exposure, rumble strip benefits, collisions with median trees, intersection safety, accident reconstruction, safety effects of speed limit changes, geometric design and head-on crashes, deer-vehicle crashes, sport utility vehicle rollover, vehicle occupancy and crash risk, a logit model for studying injury severity, abdominal injuries in rail passengers, healthy transport policies, and meta-analysis.