The objective of this study was to collect data and information from a sample of chemical manufacturing facilities and facilities which use chemicals in other processes to determine what kinds of procedures are currently in practice and to develop a set of recommended procedures which can be used to minimize the possibility of toxic chemical releases. In order to accomplish this task, the authors developed a methodology for collecting data and information concerning procedures currently being practiced to eliminate or reduce toxic chemical spills and releases. In essence, this approach divides the project into three phases: what kinds of procedures are currently being used by the chemical industry and other facilities which use toxic chemicals; what type of toxic chemical release accidents and injuries occur in these facilities; finally, how can this information be integrated into a set of recommended procedures which will decrease the likelihood of a toxic chemical release and, if one does occur, will minimize the exposure and severity of exposure to employees. This report describes both the metholodogy used and the results of its application to the chemical industry. This report provides data collected from fifteen chemical plants and facilities which use toxic chemicals.