This report describes the substance of the various interventions implemented by the HSRC and its donor partners in Botswana, South Africa and Zimbabwe, as part of the research-driven, multi-country and multi-site intervention project on orphans and vulnerable children (OVC), funded by the WK Kellogg Foundation. The report provides information on what is happening on the ground and also the basic data required to develop 'models of best practice'. It is organised according to the project's four focus areas: home-based, child-centred development programmes; family and household support programmes; strengthening of community-support systems and HIV/AIDS awareness, advocacy and policy programmes, reported by country. The main purpose of the OVC project is to develop 'models of best practice' that will facilitate the development of community-driven strategies for responding to the increasing burden of OVC in Africa.