The Plasma Proteins V3

The Plasma Proteins V3
Author: Frank Putnam
Publisher: Elsevier
Total Pages: 633
Release: 2012-12-02
Genre: Medical
ISBN: 0323161464

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The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume III is an eight-chapter treatise that describes the plasma proteins in a systematic integrated manner. This book presents first the perspectives and global outlook at plasma proteins, followed by a series of chapters on the well-characterized major proteins, with particular emphasis on immunoglobulins. Other chapters are devoted to the integrated systems of plasma proteins, especially their structure, function, and genetic control. A chapter describes the plasma protein fractionation. The remaining chapters introduce the clinical relevance of the plasma proteins. This book will be of great value to biologists, geneticists, clinicians, and researchers.

The Plasma Proteins V5

The Plasma Proteins V5
Author: Frank Putnam
Publisher: Elsevier
Total Pages: 433
Release: 2012-12-02
Genre: Medical
ISBN: 032316174X

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The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.

The Plasma Proteins

The Plasma Proteins
Author: Frank W Putnam
Publisher: Elsevier
Total Pages: 498
Release: 2012-12-02
Genre: Medical
ISBN: 032313808X

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The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases. Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes. This monograph will be of interest to molecular biologists and biochemists.

The Plasma Proteins V4

The Plasma Proteins V4
Author: Frank Putnam
Publisher: Elsevier
Total Pages: 439
Release: 2012-12-02
Genre: Science
ISBN: 0323161731

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The Plasma Proteins: Structure, Function, and Genetic Control is a systematic account of the structure, function, and genetic control of plasma proteins. Advances in the characterization and posttranslational modification of plasma proteins are discussed, along with the structure of a variety of plasma proteins such as serum albumin, glycoproteins, and serum lipoproteins, and immunoglobulins. Comprised of six chapters, this volume begins with a review of progress in plasma proteins, focusing on their three-dimensional structure, characterization, and microheterogeneity as well as genetic polymorphism and chromosomal mapping. The second chapter gives a comprehensive summary of the structure of nearly 100 proteins, from serum albumin and glycoproteins to serum lipoproteins, thyroxine-binding proteins, and immunoglobulins. The reader is then introduced to human plasma proteins of unknown function, together with high-resolution two-dimensional electrophoretic mapping. The remaining chapters explore developments in the structural study of carbon hydrates; synthesis, structure, and function of the oligosaccharides of plasma glycoproteins; and the evolution of the vertebrate plasma proteins. This monograph will be of interest to molecular biologists and biochemists.

The Proteins Pt 4

The Proteins Pt 4
Author: Hans Neurath
Publisher: Elsevier
Total Pages: 696
Release: 2012-12-02
Genre: Science
ISBN: 0323162045

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The Proteins, Third Edition, Volume IV is a four-chapter text that explores the unifying concepts of protein chemistry and the methods of analysis that can be applied to most proteins. The first chapter deals with the biological origins and subsequent evolution of proteins. This chapter also provides the various procedures for comparing amino acid sequences and for establishing the relatedness of protein structures. A discussion on gene duplication as a principal vehicle of evolutionary change is also included in this chapter. Chapter 2 focuses on chromosomal proteins, such as those proteins associated with the genetic material of eukaryotic organisms, specifically the protamines, the histones, and the ""nonhistone"" proteins. Chapter 3 is devoted to contractile proteins of muscle. This chapter describes the molecular processes whereby chemical energy is converted into the mechanical energy required for the propulsion of living creatures. The structure and function of the individual proteins of the contractile apparatus and their organization as evidenced by light and electron microscopy and by X-ray analysis are also covered. Chapter 4 deals with collagen, an important constituent of the extracellular connective tissues in animals and one of the most abundant proteins. This chapter emphasizes the biosynthesis of collagen fibrils. Organic chemists and researchers, teachers and undergraduate students will find this book invaluable.

Clinical Aspects of The Plasma Proteins

Clinical Aspects of The Plasma Proteins
Author: Tadashi Kawai
Publisher: Springer Science & Business Media
Total Pages: 475
Release: 2013-03-09
Genre: Medical
ISBN: 3662062674

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It was the year of 1969 when this monograph was originally published in Japanese by Professor TADASHI KAWAI, titled as "The Plasma Proteins, Their Fundamental and Clinical Aspects." After I read through the Japanese edition, I was impressed by its rather complete coverage of the subjects and their detailed descriptions. I have felt that this excellent monograph should be distributed not only among our Japanese scien tists but also among many other colleagues throughout the world. I am happy, the refore, to know that the English edition of his monograph, partly revised, is ready to be published at this time. Professor KAWAI received his postgraduate medical training in U.S.A. for seven years, and was certified by the American Board of Pathology in both Anatomical and Clinical Pathology in Fall, 1962. Thus, I believe, he is the most suitable fellow for publishing the English edition of this kind.

Clinical Biochemistry V2

Clinical Biochemistry V2
Author: Herbert Spiegel
Publisher: Elsevier
Total Pages: 335
Release: 2012-12-02
Genre: Medical
ISBN: 0323155529

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Clinical Biochemistry: Contemporary Theories and Techniques, Volume 2 is a collection of papers that deals with coagulation chemistry, inborn errors of metabolism (IEM), and the biochemistry of aging. One paper explains the biochemistry and clinical importance of lipoprotein-X (LP-X) as a marker for obstructive jaundice and also as a pointer in the deficiency of lecithin-cholesterol acyltransferase (LCAT), a rare inborn error of metabolism. Another paper presents guidelines in determining radioimmunoassay that are used, for example, in identifying enzymes produced by various malignant lesions. One paper reviews the basic molecular events and interactions involved in the blood clotting process and its related systems. To determine inborn errors of metabolism, the investigator can use screening techniques, prenatal diagnosis or therapy, and laboratory procedures related to IEM. To correct errors at the gene level, transgenosis and genetic engineering use recombinant DNA research techniques involving the introduction of a foreign DNA into the host cell. Some examples of IEM are phenylketonuria and hyperphenylalaninemia without PKU. This collection can prove useful for the clinical chemists, endocrinologists, internists, medical practitioners, and investigators involved in research on biochemistry.