This journal was one of the most important sources of medical information in 19th-century America, publishing articles and essays on topics ranging from public health and hygiene to surgery and anatomy. Founded by Samuel L. Mitchill in 1797, it was widely read by physicians, academics, and other medical professionals, and played a key role in advancing the state of medical knowledge in the United States. The journal is a fascinating window into the world of medicine in the early days of the Republic. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.