Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

Download Molecular Biology of The Cell Book in PDF, Epub and Kindle

DNA Repair and Mutagenesis

DNA Repair and Mutagenesis
Author: Errol C. Friedberg
Publisher: American Society for Microbiology Press
Total Pages: 2587
Release: 2005-11-22
Genre: Science
ISBN: 1555813194

Download DNA Repair and Mutagenesis Book in PDF, Epub and Kindle

An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Concepts of Biology

Concepts of Biology
Author: Samantha Fowler
Publisher:
Total Pages: 618
Release: 2018-01-07
Genre: Science
ISBN: 9789888407453

Download Concepts of Biology Book in PDF, Epub and Kindle

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

The Nucleolus

The Nucleolus
Author: Mark O. J. Olson
Publisher: Springer Science & Business Media
Total Pages: 434
Release: 2011-09-15
Genre: Science
ISBN: 1461405149

Download The Nucleolus Book in PDF, Epub and Kindle

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.

Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome
Author: National Research Council
Publisher: National Academies Press
Total Pages: 128
Release: 1988-01-01
Genre: Science
ISBN: 0309038405

Download Mapping and Sequencing the Human Genome Book in PDF, Epub and Kindle

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Recombinational Repair of DNA Damage

Recombinational Repair of DNA Damage
Author: Andrei Kuzminov
Publisher: Landes Bioscience
Total Pages: 234
Release: 1996
Genre: Medical
ISBN:

Download Recombinational Repair of DNA Damage Book in PDF, Epub and Kindle

Untangling the Double Helix

Untangling the Double Helix
Author: James C. Wang
Publisher:
Total Pages: 252
Release: 2009
Genre: DNA topoisomerases
ISBN:

Download Untangling the Double Helix Book in PDF, Epub and Kindle

The problem of unraveling two intertwined strands during the duplication of DNA was recognized shortly after the proposal of the DNA double helix structure in 1953. A group of enzymes called DNA topoisomerases solve this problem by breaking and rejoining DNA molecules in a controlled manner, thereby allowing strands to be passed through each other and thus untangled—not just during DNA replication, but also during many other basic cellular processes. Because of their intimate involvement in the workings of the cell, topoisomerases are also the logical targets of many antibiotics (including Cipro) and anticancer agents. This book, written by James Wang, the discoverer of the first topoisomerase and a leader in the field since, presents ten chapters covering the historical backdrop of the DNA entanglement problem and the discovery of the DNA topoisomerases, how DNA topoisomerases perform their magic in DNA replication, transcription, genetic recombination and chromosome condensation, and how they are targets of therapeutic agents. The book should appeal to readers from undergraduates upwards with interests in the biological and clinical aspects of topoisomerase function, or in the mathematics and physics of topology.

The Double Helix

The Double Helix
Author: James D. Watson
Publisher: Signet Book
Total Pages: 143
Release: 1969-02
Genre: DNA.
ISBN: 9780451037701

Download The Double Helix Book in PDF, Epub and Kindle

Since its publication in 1968, The Double Helix has given countless readers a rare and exciting look at one highly significant piece of scientific research-Watson and Crick's race to discover the molecular structure of DNA.

Homologous Recombination

Homologous Recombination
Author: Andres Aguilera
Publisher: Humana
Total Pages: 557
Release: 2020-10-17
Genre: Medical
ISBN: 9781071606438

Download Homologous Recombination Book in PDF, Epub and Kindle

This volume explores homologous recombination’s (HR) essential role in meiotic and somatic cells. It discusses the analysis of different steps of the HR process from the genetic, molecular biology, and cell biology perspectives. Using a variety of model systems, chapters in this book cover topics such as the genome-wide mapping of DNA double-strand breaks (DSB); analysis of DNA-end resection and recombination intermediates by gel electrophoresis and southern blotting; cell-based monitoring of HR activity in meiotic and mitotic cells; in vitro analysis of branch migration, DNA strand exchange and Holliday junction resolution; or super resolution imaging of HR repair at collapsed replication forks. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Homologous Recombination: Methods and Protocols is a valuable resource that uses both classical and more recent approaches to answer questions on the HR mechanism. It is a useful tool for scientists working on the field of genome integrity, as well as those working in cancer biology and DNA repair.

Principles of Biology

Principles of Biology
Author: Lisa Bartee
Publisher:
Total Pages:
Release: 2017
Genre:
ISBN: 9781636350417

Download Principles of Biology Book in PDF, Epub and Kindle

The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.