Templated Organic Synthesis

Templated Organic Synthesis
Author: François Diederich
Publisher: John Wiley & Sons
Total Pages: 431
Release: 2008-07-11
Genre: Science
ISBN: 3527613536

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Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.

Metal Mediated Template Synthesis of Ligands

Metal Mediated Template Synthesis of Ligands
Author: Otilia Costisor
Publisher: World Scientific
Total Pages: 316
Release: 2004
Genre: Science
ISBN: 9789812794819

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This book surveys the relatively new area of the synthesis of organic ligands when metal ions act as a template. In the last fifty years this field has undergone an explosive development, marked by a great amount of literature. The material in the book has been arranged according to the type of chemical reaction involved. In this frame, the basic principles of metal template reactions and the shape of the molecules are considered. Designed to satisfy the demands of students, young researchers doing their PhDs, and those working in the field of coordination chemistry, the book details the role of the metal ions and the specific properties of the formed complexes. Metal Mediated Template Synthesis of Ligands offers a comprehensive analysis with wide-ranging references and provides an extensive overview of research on metal-directed organic ligands over the past five decades. Contents: The Template Effect; Alkylation Reactions; Schiff Condensation; Mannich Condensation; Self Condensation of Nitriles; Self-Assembled Systems. Readership: Upper level undergraduates, graduate students, academics, researchers industrialists in inorganic, solid-state, supramolecular and organic chemistry.

Expanding the Scope of DNA-templated Organic Synthesis and in Vitro Selection

Expanding the Scope of DNA-templated Organic Synthesis and in Vitro Selection
Author: Thomas Marshall Snyder
Publisher:
Total Pages: 278
Release: 2007
Genre: Biochemical templates
ISBN: 9780549278948

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First, we describe a strategy for performing ordered multistep synthesis in a single solution. This system makes use of temperature-sensitive variations in DNA secondary structure to orchestrate an ordered multistep synthesis of a triolefin and a tripeptide in a single solution. This methodology provides a faster, higher-yielding route to multistep DNA-templated products and represents a mode of controlling chemical reactivity that is not accessible in traditional flask-based reaction formats.

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author: Michael Harmata
Publisher: Academic Press
Total Pages: 448
Release: 2004-06-15
Genre: Science
ISBN: 9780124502833

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This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. It provides a window into the world of design, function and synthesis that is at the leading edge of the molecular frontier.

Click Reactions in Organic Synthesis

Click Reactions in Organic Synthesis
Author: Srinivasan Chandrasekaran
Publisher: John Wiley & Sons
Total Pages: 360
Release: 2016-09-13
Genre: Science
ISBN: 3527339167

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Endlich ein Buch zu Click-Reaktionen mit Schwerpunkt auf der organischen Synthese. Beschrieben werden das Click-Konzept, die zugrunde liegenden Mechanismen und Hauptanwendungsgebiete. NÜTZLICH: Die Click-Chemie ist ein wirkungsvoller Ansatz, um auf einfache Weise komplexe organische Moleküle aus verfügbaren Ausgangsmaterialien zu erzeugen ? der Traum jedes Organikers. EINZIGARTIGER SCHWERPUNKT: Aufgrund des besonderen Schwerpunkts auf der organischen Synthese ist dieses Buch für jeden Synthesechemiker von hohem Interesse. HILFREICH: Click-Reaktionen sind stereospezifisch, einfach durchzuführen, hoch ergiebig und lassen sich in einfach zu entfernenden oder nicht schädlichen Lösungsmitteln durchführen. INTERDISZIPLINÄR: Das Click-Konzept ist bei der Herstellung natürlicher Produkte, bioaktiver Verbindungen, von Kohlenhydraten, Arzneimitteln, Polymeren, supramolekularer Strukturen und Materialien weit verbreitet.

Template Synthesis of Macrocyclic Compounds

Template Synthesis of Macrocyclic Compounds
Author: N. V. Gerbeleu
Publisher: John Wiley & Sons
Total Pages: 574
Release: 2008-07-11
Genre: Science
ISBN: 3527613811

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The synthesis of macrocycles is an art in itself. Template-controlled synthesis provides elegant access to fascinating macrocyclic structures. Polyazamacrocycles, crown ethers, cryptands, rotaxanes, knots -- the range of macrocyclic compounds is as broad as their potential application as molecular switches, in ion exchange, electron transfer or catalysis. This book provides authoritative information on all aspects of template-controlled macrocyclizations. It covers in depth the current state of research on template processes - novel synthetic techniques and mechanistic approaches. The critical discussion of the diverse synthetic routes includes the detailed characterization of the broad variety of macrocyclic products. References to applications of macrocyclic compounds and over 1,500 citations make this handbook an indispensable tool for chemists in academia and industry. Researchers in organic and supramolecular chemistry, biotechnology, and inorganic chemistry will find inspiration for the design, synthesis, and myriad uses of new synthetic macrocycles.

Templates in Chemistry I

Templates in Chemistry I
Author: Christoph A. Schalley
Publisher: Springer Science & Business Media
Total Pages: 294
Release: 2005-01-13
Genre: Science
ISBN: 9783540225478

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With contributions by numerous experts

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author: Michael Harmata
Publisher: Elsevier
Total Pages: 437
Release: 2004-04-19
Genre: Science
ISBN: 008051796X

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A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. - Personal accounts of research in organic chemistry. - Written by internationally renowned scientists. - Details state of the art organic synthesis.

Sequence-Controlled Polymers

Sequence-Controlled Polymers
Author: Jean-François Lutz
Publisher: John Wiley & Sons
Total Pages: 532
Release: 2018-04-09
Genre: Technology & Engineering
ISBN: 3527342370

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Edited by a leading authority in the field, the first book on this important and emerging topic provides an overview of the latest trends in sequence-controlled polymers. Following a brief introduction, the book goes on to discuss various synthetic approaches to sequence-controlled polymers, including template polymerization, genetic engineering and solid-phase chemistry. Moreover, monomer sequence regulation in classical polymerization techniques such as step-growth polymerization, living ionic polymerizations and controlled radical polymerizations are explained, before concluding with a look at the future for sequence-controlled polymers. With its unique coverage of this interdisciplinary field, the text will prove invaluable to polymer and environmental chemists, as well as biochemists and bioengineers.