Synaptic Plasticity in the Hippocampus

Synaptic Plasticity in the Hippocampus
Author: Helmut L. Haas
Publisher: Springer Science & Business Media
Total Pages: 219
Release: 2012-12-06
Genre: Medical
ISBN: 364273202X

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This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

The Hippocampus Book

The Hippocampus Book
Author: Per Andersen
Publisher: Oxford University Press
Total Pages: 892
Release: 2007
Genre: Medical
ISBN: 9780195100273

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The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

The Hippocampus

The Hippocampus
Author: Ales Stuchlik
Publisher: BoD – Books on Demand
Total Pages: 180
Release: 2018-07-11
Genre: Medical
ISBN: 1789233569

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The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.

Synaptic Plasticity in the Hippocampus

Synaptic Plasticity in the Hippocampus
Author: Helmut L. Haas
Publisher: Springer Science & Business Media
Total Pages: 219
Release: 2012-12-06
Genre: Medical
ISBN: 364273202X

Download Synaptic Plasticity in the Hippocampus Book in PDF, Epub and Kindle

This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

Synaptic Plasticity in the Hippocampus

Synaptic Plasticity in the Hippocampus
Author: Helmut L. Haas
Publisher: Springer Verlag
Total Pages: 215
Release: 1988-01-01
Genre: Science
ISBN: 9780387185996

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Neurogenesis and Neural Plasticity

Neurogenesis and Neural Plasticity
Author: Catherine Belzung
Publisher: Springer Science & Business Media
Total Pages: 447
Release: 2014-07-08
Genre: Medical
ISBN: 364236232X

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This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

The Neuroscience of Adolescence

The Neuroscience of Adolescence
Author: Adriana Galván
Publisher: Cambridge University Press
Total Pages: 341
Release: 2017-07-10
Genre: Medical
ISBN: 1107089921

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Written by an award-winning developmental neuroscientist, this is a comprehensive and cutting-edge account of the latest research on the adolescent brain.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 412
Release: 2015-12-01
Genre: Medical
ISBN: 1498766579

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Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

The Neurobiology of Brain and Behavioral Development

The Neurobiology of Brain and Behavioral Development
Author: Robbin Gibb
Publisher: Academic Press
Total Pages: 496
Release: 2017-11-02
Genre: Science
ISBN: 012804084X

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The Neurobiology of Brain and Behavioral Development provides an overview of the process of brain development, including recent discoveries on how the brain develops. This book collates and integrates these findings, weaving the latest information with core information on the neurobiology of brain development. It focuses on cortical development, but also features discussions on how the other parts of the brain wire into the developing cerebral cortex. A systems approach is used to describe the anatomical underpinnings of behavioral development, connecting anatomical and molecular features of brain development with behavioral development. The disruptors of typical brain development are discussed in appropriate sections, as is the science of epigenetics that presents a novel and instructive approach on how experiences, both individual and intergenerational, can alter features of brain development. What distinguishes this book from others in the field is its focus on both molecular mechanisms and behavioral outcomes. This body of knowledge contributes to our understanding of the fundamentals of brain plasticity and metaplasticity, both of which are also showcased in this book. Provides an up-to-date overview of the process of brain development that is suitable for use as a university textbook at an early graduate or senior undergraduate level Breadth from molecular level (Chapters 5-7) to the behavioral/cognitive level (Chapters 8-12), beginning with Chapters 1-4 providing a historical context of the ideas Integrates the neurobiology of brain development and behavior, promoting the idea that animal models inform human development Presents an emphasis on the role of epigenetics and brain plasticity in brain development and behavior

The Hippocampus

The Hippocampus
Author: Philippe Taupin
Publisher: Nova Publishers
Total Pages: 156
Release: 2007
Genre: Medical
ISBN: 9781600219146

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The hippocampus , the Greek word for seahorse, is one of the most fascinating and intriguing regions of the mammalian brain. It is a bilateral incurved seahorse-shaped structure of the cerebral cortex. The hippocampus has a highly distinctive morphology. It is composed of two regions, the dentate gyrus (DG) and the Cornu Ammonis (CA). The nerve cells of the main layer of the DG and CA regions, the granule cells and pyramidal cells respectively, are organised in a tri-synaptic lamellaire circuit. The granule and pyramidal cells are glutamatergic excitatory. The granule cells elicit unique histological, biochemical, developmental, physio- and pathological features. The hippocampus is also an area of the brain that elicits a high degree of plasticity, like synaptic and phenotypic plasticity. It is also one of the few regions of the brain where neurogenesis, the generation of new nerve cells, occurs throughout adulthood. The hippocampus is involved in physio-and pathological processes, like learning and memory.