Structural Nonparametric Models for the Analysis of Longitudinal Data

Structural Nonparametric Models for the Analysis of Longitudinal Data
Author: Colin O. Wu
Publisher: Chapman and Hall/CRC
Total Pages: 400
Release: 2016-01-15
Genre: Mathematics
ISBN: 9781466516007

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This book covers the recent advancement of statistical methods for the analysis of longitudinal data. Real datasets from four large NIH-supported longitudinal clinical trials and epidemiological studies illustrate the practical applications of the statistical methods. This book focuses on the nonparametric approaches, which have gained tremendous popularity in biomedical studies. These approaches have the flexibility to answer many scientific questions that cannot be properly addressed by the existing parametric approaches, such as the linear and nonlinear mixed effects models.

Nonparametric Models for Longitudinal Data

Nonparametric Models for Longitudinal Data
Author: Colin O. Wu
Publisher: CRC Press
Total Pages: 552
Release: 2018-05-23
Genre: Mathematics
ISBN: 0429939086

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Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era of big data and precision medicine. It also provides flexible tools to describe the temporal trends, covariate effects and correlation structures of repeated measurements in longitudinal data. This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences. Features: Provides an overview of parametric and semiparametric methods Shows smoothing methods for unstructured nonparametric models Covers structured nonparametric models with time-varying coefficients Discusses nonparametric shared-parameter and mixed-effects models Presents nonparametric models for conditional distributions and functionals Illustrates implementations using R software packages Includes datasets and code in the authors’ website Contains asymptotic results and theoretical derivations

Nonparametric Regression Methods for Longitudinal Data Analysis

Nonparametric Regression Methods for Longitudinal Data Analysis
Author: Hulin Wu
Publisher: John Wiley & Sons
Total Pages: 401
Release: 2006-05-12
Genre: Mathematics
ISBN: 0470009667

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Incorporates mixed-effects modeling techniques for more powerful and efficient methods This book presents current and effective nonparametric regression techniques for longitudinal data analysis and systematically investigates the incorporation of mixed-effects modeling techniques into various nonparametric regression models. The authors emphasize modeling ideas and inference methodologies, although some theoretical results for the justification of the proposed methods are presented. With its logical structure and organization, beginning with basic principles, the text develops the foundation needed to master advanced principles and applications. Following a brief overview, data examples from biomedical research studies are presented and point to the need for nonparametric regression analysis approaches. Next, the authors review mixed-effects models and nonparametric regression models, which are the two key building blocks of the proposed modeling techniques. The core section of the book consists of four chapters dedicated to the major nonparametric regression methods: local polynomial, regression spline, smoothing spline, and penalized spline. The next two chapters extend these modeling techniques to semiparametric and time varying coefficient models for longitudinal data analysis. The final chapter examines discrete longitudinal data modeling and analysis. Each chapter concludes with a summary that highlights key points and also provides bibliographic notes that point to additional sources for further study. Examples of data analysis from biomedical research are used to illustrate the methodologies contained throughout the book. Technical proofs are presented in separate appendices. With its focus on solving problems, this is an excellent textbook for upper-level undergraduate and graduate courses in longitudinal data analysis. It is also recommended as a reference for biostatisticians and other theoretical and applied research statisticians with an interest in longitudinal data analysis. Not only do readers gain an understanding of the principles of various nonparametric regression methods, but they also gain a practical understanding of how to use the methods to tackle real-world problems.

Longitudinal Data Analysis

Longitudinal Data Analysis
Author: Garrett Fitzmaurice
Publisher: CRC Press
Total Pages: 633
Release: 2008-08-11
Genre: Mathematics
ISBN: 142001157X

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Although many books currently available describe statistical models and methods for analyzing longitudinal data, they do not highlight connections between various research threads in the statistical literature. Responding to this void, Longitudinal Data Analysis provides a clear, comprehensive, and unified overview of state-of-the-art theory

Nonparametric Regression Analysis of Longitudinal Data

Nonparametric Regression Analysis of Longitudinal Data
Author: Hans-Georg Müller
Publisher: Springer Science & Business Media
Total Pages: 208
Release: 2012-12-06
Genre: Mathematics
ISBN: 1461239265

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This monograph reviews some of the work that has been done for longitudi nal data in the rapidly expanding field of nonparametric regression. The aim is to give the reader an impression of the basic mathematical tools that have been applied, and also to provide intuition about the methods and applications. Applications to the analysis of longitudinal studies are emphasized to encourage the non-specialist and applied statistician to try these methods out. To facilitate this, FORTRAN programs are provided which carry out some of the procedures described in the text. The emphasis of most research work so far has been on the theoretical aspects of nonparametric regression. It is my hope that these techniques will gain a firm place in the repertoire of applied statisticians who realize the large potential for convincing applications and the need to use these techniques concurrently with parametric regression. This text evolved during a set of lectures given by the author at the Division of Statistics at the University of California, Davis in Fall 1986 and is based on the author's Habilitationsschrift submitted to the University of Marburg in Spring 1985 as well as on published and unpublished work. Completeness is not attempted, neither in the text nor in the references. The following persons have been particularly generous in sharing research or giving advice: Th. Gasser, P. Ihm, Y. P. Mack, V. Mammi tzsch, G . G. Roussas, U. Stadtmuller, W. Stute and R.

Methods and Applications of Longitudinal Data Analysis

Methods and Applications of Longitudinal Data Analysis
Author: Xian Liu
Publisher: Elsevier
Total Pages: 531
Release: 2015-09-01
Genre: Mathematics
ISBN: 0128014822

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Methods and Applications of Longitudinal Data Analysis describes methods for the analysis of longitudinal data in the medical, biological and behavioral sciences. It introduces basic concepts and functions including a variety of regression models, and their practical applications across many areas of research. Statistical procedures featured within the text include: descriptive methods for delineating trends over time linear mixed regression models with both fixed and random effects covariance pattern models on correlated errors generalized estimating equations nonlinear regression models for categorical repeated measurements techniques for analyzing longitudinal data with non-ignorable missing observations Emphasis is given to applications of these methods, using substantial empirical illustrations, designed to help users of statistics better analyze and understand longitudinal data. Methods and Applications of Longitudinal Data Analysis equips both graduate students and professionals to confidently apply longitudinal data analysis to their particular discipline. It also provides a valuable reference source for applied statisticians, demographers and other quantitative methodologists. From novice to professional: this book starts with the introduction of basic models and ends with the description of some of the most advanced models in longitudinal data analysis Enables students to select the correct statistical methods to apply to their longitudinal data and avoid the pitfalls associated with incorrect selection Identifies the limitations of classical repeated measures models and describes newly developed techniques, along with real-world examples.

Analysis of Longitudinal Data

Analysis of Longitudinal Data
Author: Peter Diggle
Publisher: Oxford University Press, USA
Total Pages: 397
Release: 2013-03-14
Genre: Language Arts & Disciplines
ISBN: 0199676755

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This second edition has been completely revised and expanded to become the most up-to-date and thorough professional reference text in this fast-moving area of biostatistics. It contains an additional two chapters on fully parametric models for discrete repeated measures data and statistical models for time-dependent predictors.

Modeling Longitudinal Data

Modeling Longitudinal Data
Author: Robert E. Weiss
Publisher: Springer Science & Business Media
Total Pages: 445
Release: 2005-06-28
Genre: Medical
ISBN: 0387402713

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The book features many figures and tables illustrating longitudinal data and numerous homework problems. The associated web site contains many longitudinal data sets, examples of computer code, and labs to re-enforce the material. Weiss emphasizes continuous data rather than discrete data, graphical and covariance methods, and generalizations of regression rather than generalizations of analysis of variance.

Longitudinal Analysis

Longitudinal Analysis
Author: Lesa Hoffman
Publisher: Routledge
Total Pages: 867
Release: 2015-01-30
Genre: Psychology
ISBN: 1317591089

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Longitudinal Analysis provides an accessible, application-oriented treatment of introductory and advanced linear models for within-person fluctuation and change. Organized by research design and data type, the text uses in-depth examples to provide a complete description of the model-building process. The core longitudinal models and their extensions are presented within a multilevel modeling framework, paying careful attention to the modeling concerns that are unique to longitudinal data. Written in a conversational style, the text provides verbal and visual interpretation of model equations to aid in their translation to empirical research results. Overviews and summaries, boldfaced key terms, and review questions will help readers synthesize the key concepts in each chapter. Written for non-mathematically-oriented readers, this text features: A description of the data manipulation steps required prior to model estimation so readers can more easily apply the steps to their own data An emphasis on how the terminology, interpretation, and estimation of familiar general linear models relates to those of more complex models for longitudinal data Integrated model comparisons, effect sizes, and statistical inference in each example to strengthen readers’ understanding of the overall model-building process Sample results sections for each example to provide useful templates for published reports Examples using both real and simulated data in the text, along with syntax and output for SPSS, SAS, STATA, and Mplus at www.PilesOfVariance.com to help readers apply the models to their own data The book opens with the building blocks of longitudinal analysis—general ideas, the general linear model for between-person analysis, and between- and within-person models for the variance and the options within repeated measures analysis of variance. Section 2 introduces unconditional longitudinal models including alternative covariance structure models to describe within-person fluctuation over time and random effects models for within-person change. Conditional longitudinal models are presented in section 3, including both time-invariant and time-varying predictors. Section 4 reviews advanced applications, including alternative metrics of time in accelerated longitudinal designs, three-level models for multiple dimensions of within-person time, the analysis of individuals in groups over time, and repeated measures designs not involving time. The book concludes with additional considerations and future directions, including an overview of sample size planning and other model extensions for non-normal outcomes and intensive longitudinal data. Class-tested at the University of Nebraska-Lincoln and in intensive summer workshops, this is an ideal text for graduate-level courses on longitudinal analysis or general multilevel modeling taught in psychology, human development and family studies, education, business, and other behavioral, social, and health sciences. The book’s accessible approach will also help those trying to learn on their own. Only familiarity with general linear models (regression, analysis of variance) is needed for this text.

Nonparametric Models for Longitudinal Data

Nonparametric Models for Longitudinal Data
Author: Colin O. Wu
Publisher: CRC Press
Total Pages: 512
Release: 2018-05-23
Genre: Mathematics
ISBN: 0429939078

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Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era of big data and precision medicine. It also provides flexible tools to describe the temporal trends, covariate effects and correlation structures of repeated measurements in longitudinal data. This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences. Features: • Provides an overview of parametric and semiparametric methods • Shows smoothing methods for unstructured nonparametric models • Covers structured nonparametric models with time-varying coefficients • Discusses nonparametric shared-parameter and mixed-effects models • Presents nonparametric models for conditional distributions and functionals • Illustrates implementations using R software packages • Includes datasets and code in the authors’ website • Contains asymptotic results and theoretical derivations