Solvent-free Organic Synthesis

Solvent-free Organic Synthesis
Author: Koichi Tanaka
Publisher: John Wiley & Sons
Total Pages: 476
Release: 2009-03-02
Genre: Science
ISBN: 9783527322640

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In this second edition of a best-selling handbook all the chapters have been completely revised and updated, while four completely new chapters have been added. In order to meet the needs of the practitioner, emphasis is placed on describing precisely the technology and know-how involved. Adopting a didactic and comprehensible approach, the book guides the reader through theory and applications, thus ensuring its warm welcome among the scientific community. An excellent, essential and exhaustive overview.

Solvent-free Organic Synthesis

Solvent-free Organic Synthesis
Author: Koichi Tanaka
Publisher: John Wiley & Sons
Total Pages: 442
Release: 2006-03-06
Genre: Science
ISBN: 3527605363

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The demand for increasingly clean and efficient chemical syntheses is continuously becoming more urgent from both an economic and an environmental standpoint. So-called green technologies are looking for alternatives, yet they focus on large quantities of hazardous even toxic solvents. One could even say that the best solvent is no solvent. It is against this background that chemical synthesis without the use of solvents has increasingly developed into a powerful methodology. Once the chemical reactivity is increased, the amount of initial substances needed is reduced; in particular it removes the need for the complex recycling and disposal of solvents. In this book, the third in our open "Green Chemistry" series, Koichi Tanaka describes the latest developments in this exciting field. Packed with advice on applications, this will be equally useful to practitioners in research as well as process chemists in industry, such that it is sure to become an invaluable reference source.

Modern Solvents in Organic Synthesis

Modern Solvents in Organic Synthesis
Author: Paul Knochel
Publisher: Springer
Total Pages: 217
Release: 2003-07-01
Genre: Science
ISBN: 354048664X

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In recent years the choice of a given solvent for performing a reaction has become increasingly important. More and more, selective reagents are used for chemical transformations and the choice of the solvent may be determining for reaching high reaction rates and high selectivities. The toxicity and recycling considerations have also greatly influenced the nature of the solvents used for industrial reactions. Thus, the development of reactions in water is not only important on the laboratory scale but also for industrial applications. The p- formance of metal-catalyzed reactions in water for example has led to several new hydrogenation or hydroformylation procedures with important industrial applications. The various aspects of organic chemistry in water will be prese- ed in this book. Recently, novel reaction media such as perfluorinated solvents or supercritical carbon dioxide has proven to have unique advantages leading to more practical and more efficient reactions. Especially with perfluorinated solvents, new biphasic catalyses and novel approaches to perform organic reactions have been developed. These aspects will be examined in detail in this volume. Finally, the performance of reactions in the absence of solvents will show practical alternatives for many reactions. More than ever before, the choice of the solvent or the solvent system is ess- tial for realizing many chemical transformations with the highest efficiency. This book tries to cover the more recent and important new solvents or solvent systems for both academic and industrial applications.

Solvents as Reagents in Organic Synthesis

Solvents as Reagents in Organic Synthesis
Author: Xiao-Feng Wu
Publisher: John Wiley & Sons
Total Pages: 552
Release: 2018-01-03
Genre: Science
ISBN: 352734196X

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Written by highly renowned and experienced authors, this is the only reference on the application of solvents as reagents. Clearly structured, the text describes various methods for the activation and reaction of these small molecules, highlighting the synthetic opportunities as well as process-oriented advantages. To this end, all relevant types of solvents are covered separately and emphasized with numerous synthetic examples, while taking care to explain applications so as to avoid undesired side reactions. The result is a unique resource for every synthetic chemist and reaction engineer in industry and academia working on the methodical optimization of synthetic transformations.

Catalyst-free Organic Synthesis

Catalyst-free Organic Synthesis
Author: Goutam Brahmachari
Publisher: Royal Society of Chemistry
Total Pages: 410
Release: 2017-11-06
Genre: Business & Economics
ISBN: 1782624120

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Explaining methods for carrying out chemical syntheses without the use of catalysts, this book shows how avoiding catalysts during synthesis can mean less use of toxic chemicals, environmentally damaging chemicals, or endangered elements, and lower costs.

Biphasic Chemistry and The Solvent Case

Biphasic Chemistry and The Solvent Case
Author: Jean-Philippe Goddard
Publisher: John Wiley & Sons
Total Pages: 162
Release: 2020-01-09
Genre: Science
ISBN: 111969504X

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Biphasic Chemistry and The Solvent Case examines recent improvements in reaction conditions, in order to affirm the role of chemistry in the sustainable field. This book shows that those who work within the chemistry industry support limits for the use of toxic or flammable solvents, since it reduces the purifications to simple filtrations. Thanks to commercial scavengers, solid phase syntheses are now available to all. Fluorine biphasic catalysis enables extremely efficient catalyst recycling and has a high applicability potential at the industrial level. This book also reviews the many studies that have shown that water is a solvent of choice for most synthetic reactions. Particular traits can be obtained and the effects on thermodynamics make it possible to operate at lower temperatures, thereby achieving energy savings. Finally the great diversity of application of the reactions without solvents is illustrated.

Solvents and Solvent Effects in Organic Chemistry

Solvents and Solvent Effects in Organic Chemistry
Author: Christian Reichardt
Publisher: John Wiley & Sons
Total Pages: 653
Release: 2006-03-06
Genre: Science
ISBN: 3527605673

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In most cases, every chemist must deal with solvent effects, whether voluntarily or otherwise. Since its publication, this has been the standard reference on all topics related to solvents and solvent effects in organic chemistry. Christian Reichardt provides reliable information on the subject, allowing chemists to understand and effectively use these phenomena. 3rd updated and enlarged edition of a classic 35% more contents excellent, proven concept includes current developments, such as ionic liquids indispensable in research and industry From the reviews of the second edition: "...This is an immensely useful book, and the source that I would turn to first when seeking virtually any information about solvent effects." —Organometallics

Physical Chemistry of Organic Solvent Systems

Physical Chemistry of Organic Solvent Systems
Author: A. Covington
Publisher: Springer Science & Business Media
Total Pages: 821
Release: 2012-12-06
Genre: Science
ISBN: 1468419595

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We believe this to be the first monograph devoted to the physicochemical properties of solutions in organic solvent systems. Although there have 1 been a number of books on the subject of non-aqueous solvents - 4, they have been devoted, almost entirely, to inorganic solvents such as liquid ammonia, liquid sulphur dioxide, etc. A variety of new solvents such as dimethylformamide, dimethylsulphoxide and propylene carbonate have become commercially available over the last twenty years. Solutions in these solvents are of technological interest in connection with novel battery systems and chemical synthesis, while studies of ion solvation and transport properties have fostered academic interest. This monograph is primarily concerned with electrolytic solutions although discussion of non-electrolyte solutions has not been excluded. We have deliberately omitted consideration of the important area of solvent extraction, since this has been adequately covered elsewhere. Our contributors were asked to review and discuss their respective areas with particular reference to differences in technique necessitated by use of non-aqueous solvents while not reiterating facts well-known from experience with aqueous solutions. We have striven to build their contributions into a coherent and consistent whole. We thank our con tributors for following our suggestions so ably and for their forebearance in the face of our editorial impositions.

Sustainable Organic Synthesis

Sustainable Organic Synthesis
Author: Dr Stefano Protti
Publisher: Royal Society of Chemistry
Total Pages: 602
Release: 2021-10-29
Genre: Science
ISBN: 1839162031

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Recent years have seen huge growth in the area of sustainable chemistry. In order to meet the chemical needs of the global population whilst minimising impacts on health and the environment it is essential to keep reconsidering and improving synthetic processes. Sustainable Organic Synthesis is a comprehensive collection of contributions, provided by specialists in Green Chemistry, covering topics ranging from catalytic approaches to benign and alternative reaction media, and innovative and more efficient technologies.

Mechanochemical Organic Synthesis

Mechanochemical Organic Synthesis
Author: Davor Margetic
Publisher: Elsevier
Total Pages: 388
Release: 2016-04-23
Genre: Science
ISBN: 0128025255

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Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area. Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Integrates advances in green chemistry research into industrial applications and process development Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds