Silk-based Drug Delivery Systems

Silk-based Drug Delivery Systems
Author: Elia Bari
Publisher: Royal Society of Chemistry
Total Pages: 243
Release: 2020-10-07
Genre: Science
ISBN: 1788017722

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Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Silk Fibroin Nanoparticles

Silk Fibroin Nanoparticles
Author: Mercedes G. Montalb√°n
Publisher:
Total Pages: 0
Release: 2019
Genre: Technology & Engineering
ISBN:

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The use of nanoparticles in biomedical fields is a very promising scientific area and has aroused the interest of researchers in the search for new biodegradable, biocompatible and non-toxic materials. This chapter is based on the features of the biopolymer silk fibroin and its applications in nanomedicine. Silk fibroin, obtained from the Bombyx mori silkworm, is a natural polymeric biomaterial whose main features are its amphiphilic chemistry, biocompatibility, biodegradability, excellent mechanical properties in various material formats, and processing flexibility. All of these properties make silk fibroin a useful candidate to act as nanocarrier. In this chapter, the structure of silk fibroin, its biocompatibility and degradability are reviewed. In addition, an intensive review on the silk fibroin nanoparticle synthesis methods is also presented. Finally, the application of the silk fibroin nanoparticles for drug delivery acting as nanocarriers is detailed.

Drug Delivery Systems Based on Supercritical-CO2 Process

Drug Delivery Systems Based on Supercritical-CO2 Process
Author: Patel Jayvadan
Publisher: LAP Lambert Academic Publishing
Total Pages: 88
Release: 2012-07
Genre:
ISBN: 9783659176081

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Supercritical fluid (SCF) technology has become an important tool of materials processing in the last two decades. Supercritical CO2 and H2O are extensively being used in the preparation of a great variety of nanomaterials. The greatest requirement in the application of nanomaterials is its size and morphology control, which determine the application potential of the nanoparticles, as their properties vary significantly with size. The aim of this chapter is to provide a critical review of the recent advances in the use of supercritical fluids for the preparation and control of specific physical forms of pharmaceutical substances with particular attention to those used for the preparation of drug delivery systems.

Silk Fibroin Nanoparticles

Silk Fibroin Nanoparticles
Author: John D. Totten
Publisher:
Total Pages: 0
Release: 2019
Genre:
ISBN:

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Overall, this thesis accomplished in vitro analysis of silk fibroin nanoparticle drug delivery performance, macrophage interactions and endocytic uptake. These findings indicate that silk fibroin nanoparticles are emerging as an interesting biopolymer for anticancer applications. Work presented in this thesis provides a foundation to now move to pre-clinical in vivo studies.

Emerging Technologies for Nanoparticle Manufacturing

Emerging Technologies for Nanoparticle Manufacturing
Author: Jayvadan K. Patel
Publisher: Springer Nature
Total Pages: 611
Release: 2021-06-23
Genre: Medical
ISBN: 3030507033

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This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges.

Biopolymer-Based Formulations

Biopolymer-Based Formulations
Author: Kunal Pal
Publisher: Elsevier
Total Pages: 966
Release: 2020-01-18
Genre: Technology & Engineering
ISBN: 0128168986

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Biopolymer-Based Formulations: Biomedical and Food Applications presents the latest advances in the synthesis and characterization of advanced biopolymeric formulations and their state-of-the-art applications across biomedicine and food science. Sections cover the fundamentals, applications, future trends, environmental, ethical and medical considerations, and biopolymeric architectures that are organized in nano, micro and macro scales. The final section of the book focuses on novel applications and recent developments. This book is an essential resource for researchers, scientists and advanced students in biopolymer science, polymer science, polymer chemistry, polymer composites, plastics engineering, biomaterials, materials science, biomedical engineering, and more. It will also be of interest to R&D professionals, scientists and engineers across the plastics, food, biomedical and pharmaceutical industries. Provides in-depth coverage of methods for the characterization of the physical properties of biopolymeric architectures Supports a range of novel applications, including scaffolds, implant coatings, drug delivery, and nutraceutical encapsulation systems Includes the use of experimental data and mathematical modeling, thus enabling the reader to analyze and compare the properties of different polymeric gels

Recent Advances in Ionic Liquids

Recent Advances in Ionic Liquids
Author: Mohammed Rahman
Publisher: BoD – Books on Demand
Total Pages: 194
Release: 2018-09-26
Genre: Science
ISBN: 1789841178

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Recent Advances in Ionic Liquids contains research on the preparation, characterization, and potential applications of stable ionic liquids (ILs). ILs are a class of low- and stable-melting point, ionic compounds that have a variety of properties allowing many of them to be sustainable green solvents. It is promising novel research from top to bottom and has received a lot of interest over the last few decades. It covers the advanced topics of physical, catalytic, chemical, polymeric, and potential applications of ILs. This book features interesting reports on cutting-edge science and technology related to the preparation, characterization, polymerization, and potential applications of ILs. This potentially unique work offers various approaches on the R

Springer Handbook of Aerogels

Springer Handbook of Aerogels
Author: Michel A. Aegerter
Publisher: Springer Nature
Total Pages: 1778
Release: 2023-10-01
Genre: Technology & Engineering
ISBN: 3030273229

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This indispensable handbook provides comprehensive coverage of the current state-of-the-art in inorganic, organic, and composite aerogels – from synthesis and characterization to cutting-edge applications and their potential market impact. Built upon Springer’s successful Aerogels Handbook published in 2011, this handbook features extensive revisions and timely updates, reflecting the changes in this fast-growing field. Aerogels are the lightest solids known to man. Up to 1000 times lighter than glass and with a density only four times that of air, they possess extraordinarily high thermal, electrical, and acoustic insulation properties, and boast numerous entries in Guinness World Records. Originally based on silica, R&D efforts have extended this class of materials to incorporate non-silicate inorganic oxides, natural and synthetic organic polymers, carbon, metal, and ceramic materials. Composite systems involving polymer-crosslinked aerogels and interpenetrating hybrid networks have been developed and exhibit remarkable mechanical strength and flexibility. Even more exotic aerogels based on clays, chalcogenides, phosphides, quantum dots, and biopolymers such as chitosan are opening new applications for the construction, transportation, energy, defense and healthcare industries. Applications in electronics, chemistry, mechanics, engineering, energy production and storage, sensors, medicine, nanotechnology, military and aerospace, oil and gas recovery, thermal insulation, and household uses are being developed. Readers of this fully updated and expanded edition will find an exhaustive source for all aerogel materials known today, their fabrication, upscaling aspects, physical and chemical properties, and the most recent advances towards applications and commercial use. This key reference is essential reading for a combined audience of graduate students, academic researchers, and industry professionals.