Revisiting Race in a Genomic Age

Revisiting Race in a Genomic Age
Author: Barbara A. Koenig
Publisher: Rutgers University Press
Total Pages: 396
Release: 2008
Genre: Science
ISBN: 081354324X

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Essays explore a range of topics that include drug development and the production of race-based therapeutics, the ways in which genetics could contribute to future health disparities, the social implications of ancestry mapping, and the impact of emerging race and genetics research on public policy and the media.

Reconsidering Race

Reconsidering Race
Author: Kazuko Suzuki
Publisher: Oxford University Press
Total Pages: 329
Release: 2018
Genre: Political Science
ISBN: 019046528X

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To better understand the idea of "race" in the postgenomic age, social science ought to move beyond merely repeating the "race is a social construct" mantra. This collection directly engages the interface between social-scientific and natural-scientific perspectives on race considering recent developments in genomics. The book provides views that go beyond US-centered or Western-based paradigms on race.

Genetics and the Unsettled Past

Genetics and the Unsettled Past
Author: Keith Wailoo
Publisher: Rutgers University Press
Total Pages: 371
Release: 2012-03-15
Genre: Social Science
ISBN: 0813553369

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Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

Sex Itself

Sex Itself
Author: Sarah S. Richardson
Publisher: University of Chicago Press
Total Pages: 320
Release: 2013-12-13
Genre: Science
ISBN: 022608471X

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Human genomes are 99.9 percent identical—with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.

A Troublesome Inheritance

A Troublesome Inheritance
Author: Nicholas Wade
Publisher: Penguin
Total Pages: 249
Release: 2014-05-06
Genre: Science
ISBN: 0698163796

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Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story Fewer ideas have been more toxic or harmful than the idea of the biological reality of race, and with it the idea that humans of different races are biologically different from one another. For this understandable reason, the idea has been banished from polite academic conversation. Arguing that race is more than just a social construct can get a scholar run out of town, or at least off campus, on a rail. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years—to be lactose tolerant, for example, and to survive at high altitudes. Race is not a bright-line distinction; by definition it means that the more human populations are kept apart, the more they evolve their own distinct traits under the selective pressure known as Darwinian evolution. For many thousands of years, most human populations stayed where they were and grew distinct, not just in outward appearance but in deeper senses as well. Wade, the longtime journalist covering genetic advances for The New York Times, draws widely on the work of scientists who have made crucial breakthroughs in establishing the reality of recent human evolution. The most provocative claims in this book involve the genetic basis of human social habits. What we might call middle-class social traits—thrift, docility, nonviolence—have been slowly but surely inculcated genetically within agrarian societies, Wade argues. These “values” obviously had a strong cultural component, but Wade points to evidence that agrarian societies evolved away from hunter-gatherer societies in some crucial respects. Also controversial are his findings regarding the genetic basis of traits we associate with intelligence, such as literacy and numeracy, in certain ethnic populations, including the Chinese and Ashkenazi Jews. Wade believes deeply in the fundamental equality of all human peoples. He also believes that science is best served by pursuing the truth without fear, and if his mission to arrive at a coherent summa of what the new genetic science does and does not tell us about race and human history leads straight into a minefield, then so be it. This will not be the last word on the subject, but it will begin a powerful and overdue conversation.

Race in a Bottle

Race in a Bottle
Author: Jonathan Kahn
Publisher: Columbia University Press
Total Pages: 329
Release: 2012-12-11
Genre: Medical
ISBN: 0231531273

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At a ceremony announcing the completion of the first draft of the human genome in 2000, President Bill Clinton declared, "I believe one of the great truths to emerge from this triumphant expedition inside the human genome is that in genetic terms, all human beings, regardless of race, are more than 99.9 percent the same." Yet despite this declaration of unity, biomedical research has focused increasingly on mapping that.1 percent of difference, particularly as it relates to race. This trend is exemplified by the drug BiDil. Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was originally touted as a pathbreaking therapy to treat heart failure in black patients and help underserved populations. Upon closer examination, however, Jonathan Kahn reveals a far more complex story. At the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked. Using BiDil as a central case study, Kahn broadly examines the legal and commercial imperatives driving the expanding role of race in biomedicine, even as scientific advances in genomics could render the issue irrelevant. He surveys the distinct politics informing the use of race in medicine and the very real health disparities caused by racism and social injustice that are now being cast as a mere function of genetic difference. Calling for a more reasoned approach to using race in biomedical research and practice, Kahn asks readers to recognize that, just as genetics is a complex field requiring sensitivity and expertise, so too is race, particularly in the field of biomedicine.

A Cultural History of Race in the Modern and Genomic Age

A Cultural History of Race in the Modern and Genomic Age
Author: Tanya Maria Golash-Boza
Publisher: Bloomsbury Publishing
Total Pages: 233
Release: 2023-06-01
Genre: History
ISBN: 1350300233

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The period from the 1920s to the present is marked by the rise of eugenics, the expansion and hardened enforcement of immigration laws, legal apartheid, the continuance of race pseudoscience, and the rise of human and civil rights discourse in response. Eugenics programmes in the early 20th century focused on sterilization and evolved into unimaginable horrors with the Nazi regime in Germany. Countries in Europe and across the Americas have used immigration policies to shape the racial composition of their territories. Legal apartheid has been slowly dismantled in the United States and South Africa yet continues to have enduring consequences. Eugenics today persists in various permutations of race science. Leaders and activists have drawn from civil and human rights discourses to fight back against the persistence of racial inequalities and racialized discourses in the 21st century. We can look back on history and see that the Holocaust was a tragedy of historic proportions, yet the tradition of scientific racism that led to the Holocaust continues. We can look back and see that the internment of the Japanese during the Second World War was a horrific injustice, yet detention camps filled with Central Americans continue to proliferate in the United States and refugee camps around the world are overflowing. As this volume makes clear, racism is an ideology that is adept at changing with the times, yet never dissipates

Race to the Finish

Race to the Finish
Author: Jenny Reardon
Publisher: Princeton University Press
Total Pages: 249
Release: 2009-02-09
Genre: Science
ISBN: 1400826403

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In the summer of 1991, population geneticists and evolutionary biologists proposed to archive human genetic diversity by collecting the genomes of "isolated indigenous populations." Their initiative, which became known as the Human Genome Diversity Project, generated early enthusiasm from those who believed it would enable huge advances in our understanding of human evolution. However, vocal criticism soon emerged. Physical anthropologists accused Project organizers of reimporting racist categories into science. Indigenous-rights leaders saw a "Vampire Project" that sought the blood of indigenous people but not their well-being. More than a decade later, the effort is barely off the ground. How did an initiative whose leaders included some of biology's most respected, socially conscious scientists become so stigmatized? How did these model citizen-scientists come to be viewed as potential racists, even vampires? This book argues that the long abeyance of the Diversity Project points to larger, fundamental questions about how to understand knowledge, democracy, and racism in an age when expert claims about genomes increasingly shape the possibilities for being human. Jenny Reardon demonstrates that far from being innocent tools for fighting racism, scientific ideas and practices embed consequential social and political decisions about who can define race, racism, and democracy, and for what ends. She calls for the adoption of novel conceptual tools that do not oppose science and power, truth and racist ideologies, but rather draw into focus their mutual constitution.

Redefining Race

Redefining Race
Author: Dina G. Okamoto
Publisher: Russell Sage Foundation
Total Pages: 262
Release: 2014-09-25
Genre: Social Science
ISBN: 1610448456

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In 2012, the Pew Research Center issued a report that named Asian Americans as the “highest-income, best-educated, and fastest-growing racial group in the United States.” Despite this seemingly optimistic conclusion, over thirty Asian American advocacy groups challenged the findings. As many pointed out, the term “Asian American” itself is complicated. It currently denotes a wide range of ethnicities, national origins, and languages, and encompasses a number of significant economic and social disparities. In Redefining Race, sociologist Dina G. Okamoto traces the complex evolution of this racial designation to show how the use of “Asian American” as a panethnic label and identity has been a deliberate social achievement negotiated by members of this group themselves, rather than an organic and inevitable process. Drawing on original research and a series of interviews, Okamoto investigates how different Asian ethnic groups in the U.S. were able to create a collective identity in the wake of the Civil Rights movement in the 1960s. Okamoto argues that a variety of broad social forces created the conditions for this developing panethnic identity. Racial segregation, for example, shaped how Asian immigrants of different national origins were distributed in similar occupations and industries. This segregation of Asians within local labor markets produced a shared experience of racial discrimination, which encouraged Asian ethnic groups to develop shared interests and identities. By constructing a panethnic label and identity, ethnic group members took part in creating their own collective histories, and in the process challenged and redefined current notions of race. The emergence of a panethnic racial identity also depended, somewhat paradoxically, on different groups organizing along distinct ethnic lines in order to gain recognition and rights from the larger society. According to Okamoto, these ethnic organizations provided the foundation necessary to build solidarity within different Asian-origin communities. Leaders and community members who created inclusive narratives and advocated policies that benefited groups beyond their own were then able to move these discrete ethnic organizations toward a panethnic model. For example, a number of ethnic-specific organizations in San Francisco expanded their services and programs to include other ethnic group members after their original constituencies dwindled. A Laotian organization included refugees from different parts of Asia, a Japanese organization began to advocate for South Asian populations, and a Chinese organization opened its doors to Filipinos and Vietnamese. As Okamoto argues, the process of building ties between ethnic communities while also recognizing ethnic diversity is the hallmark of panethnicity. Redefining Race is a groundbreaking analysis of the processes through which group boundaries are drawn and contested. In mapping the genesis of a panethnic Asian American identity, Okamoto illustrates the ways in which concepts of race continue to shape how ethnic and immigrant groups view themselves and organize for representation in the public arena.

The Enculturated Gene

The Enculturated Gene
Author: Duana Fullwiley
Publisher: Princeton University Press
Total Pages: 369
Release: 2011-11-07
Genre: Social Science
ISBN: 1400840414

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In the 1980s, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. After casual observations of how patients managed this painful blood disorder, the researchers in question postulated that the Senegalese type was less severe. The Enculturated Gene traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell "mild" in a social setting where public health priorities and economic austerity programs have forced people to improvise informal strategies of care. Duana Fullwiley shows how geneticists, who were fixated on population differences, never investigated the various modalities of self-care that people developed in this context of biomedical scarcity, and how local doctors, confronted with dire cuts in Senegal's health sector, wittingly accepted the genetic prognosis of better-than-expected health outcomes. Unlike most genetic determinisms that highlight the absoluteness of disease, DNA haplotypes for sickle cell in Senegal did the opposite. As Fullwiley demonstrates, they allowed the condition to remain officially invisible, never to materialize as a health priority. At the same time, scientists' attribution of a less severe form of Senegalese sickle cell to isolated DNA sequences closed off other explanations of this population's measured biological success. The Enculturated Gene reveals how the notion of an advantageous form of sickle cell in this part of West Africa has defined--and obscured--the nature of this illness in Senegal today. Some images inside the book are unavailable due to digital copyright restrictions.