Context: Female athletes returning to sports after being reconstructed with hamstring autografts has not been widely discussed in the literature. Objective: To evaluate reconstructed anterior cruciate ligament failures in a population of female athletes returning to competitive sports. Design: Restrospective Study. Setting: A private orthopaedic clinic. Patients or Other Participants: Female atheletes ranging in age from 13-25 that participated in sports before and after anterior cruciate ligament reconstruction using only hamstring autografts. Two groups were compared, a Non-Failure Group to a Failure Group. The sports were divided into Level 1 and Level 2 soprts for this study. Data Collection and Analysis: Data collection was performed by one practitioner. Demographic factors were collected from medical records with IRB approval. All factors that may have lead to the failure of the reconstructed anterior cruciate ligament in female athletes were collected. Statistical significance was set at p (less than or equal to) 0.05. Results: The mean follow-up time was 24 (plus or minus) 6 months on all the participants. Return to pre-injury status and athletics took the Non-Failure Group 158 days from surgery compared to the Failure Group who took 141 days to return to athletic competition. Sports returned to after reconstructive surgery using the hamstring autograft compared between the two groups was statistically significant. Conclusions: Repeat ACL injury occured in 14% of the athletes in the first 8 months after the index reconstruction. The factors that increased the risk of repeat ACL injury included a return to competitive sports and the days between surgery and return to pre-injury status. Factors such as age, meniscal, and other knee ligament injuries during the index ACL rupture are believed to increase the risk of injury, but were not found to influence ACL graft ruptures.