Restorative Neurology of Spinal Cord Injury

Restorative Neurology of Spinal Cord Injury
Author: Milan R. Dimitrijevic
Publisher: OUP USA
Total Pages: 337
Release: 2012-01-12
Genre: Medical
ISBN: 0199746508
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Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach. Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.

Principles and Practice of Restorative Neurology

Principles and Practice of Restorative Neurology
Author: Robert R Young
Publisher: Butterworth-Heinemann
Total Pages: 236
Release: 2013-10-22
Genre: Medical
ISBN: 1483163229
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Principles and Practice of Restorative Neurology is a collection of topics in clinical neurology where progress through research has brought concepts of patient management. The collection emphasizes research done clinically and in experimental laboratories and attempts to discuss restorative neurology in the larger context, encompassing biology, neurobiology, and rehabilitative engineering. The book discusses the concept that neurology should be more therapeutic instead of being just diagnostic because of advances in techniques and drugs. An epidemiology of disability and the evaluation of restorative neurology are explained. The text also presents the developments in the pharmacotherapy of major neurological disorders, such as Parkinson's disease, dementia, and stroke. The use of biomechanical or rehabilitation engineering to treat impaired or lost functions in a patient is compared; the feedback mechanisms and the kinds of treatment including microsurgery, nuerostimulation methods, surgery, and molecular genetics that are applied to specific disorders are discussed extensively. The book also reviews the approaches of gene correction for disorders in the central nervous system. Finally, the future needs of neurology in terms of diagnosis and treatments are dealt with as more research, techniques, and drugs are being discovered and proved useful. The collection is intended for neurologists, neurologists in training, and other physicians whose work lies with neurological disorders. The book can also prove useful for practitioners and academicians in the fields of neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

Neurological Aspects of Spinal Cord Injury

Neurological Aspects of Spinal Cord Injury
Author: Norbert Weidner
Publisher: Springer
Total Pages: 761
Release: 2017-06-06
Genre: Medical
ISBN: 3319462938
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This clinically focused book aims to cover for the first time all of the neurological aspects relevant to the diagnosis and treatment of spinal cord disease. Furthermore, innovative neurorestorative therapeutic strategies - aiming for repair of the damaged spinal cord and/or reorganization of the remaining nervous system - with significant potential for translation into clinical routine are presented. The book covers a comprehensive list of topics, including epidemiology, neuroanatomy, etiology of compressive and non-compressive spinal cord injury, imaging, neurophysiology, neurological sequelae, and complications with emphasis on dysfunction of the autonomic nervous system. Both clinically established and preclinical therapies are discussed in detail. The book is suited for trainees and practicing clinicians including neurologists, spine surgeons, rehabilitation specialists, neuroradiologists, and occupational/physical therapists; it will also be of value to neuroscientists involved in research into spinal cord disease.

Spinal Cord Injury

Spinal Cord Injury
Author: Joost Verhaagen
Publisher: Newnes
Total Pages: 677
Release: 2012-12-31
Genre: Medical
ISBN: 0444535071
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Handbook of Clinical Neurology: Spinal Cord Injury summarizes advances in the clinical diagnosis, monitoring, prognostication, treatment, and management of spinal cord injuries. More specifically, it looks at new and important developments in areas such as high-resolution noninvasive neuroimaging, surgery, and electrical stimulation of motor, respiratory, bladder, bowel, and sexual functions. It also reviews the latest insights into spontaneous regeneration and recovery of function following rehabilitation, with emphasis on novel therapeutic strategies, such as gene therapy, transcranial stimulation, brain-machine interfaces, pharmacological approaches, molecular target discovery, and the use of olfactory ensheathing cells, stem cells, and precursor cells. Organized in five sections, the book begins with an overview of the development, maturation, biomechanics, and anatomy of the spinal cord before proceeding with a discussion of clinical diagnosis and prognosis as well as natural recovery, ambulation, and function following spinal cord injury. It then examines clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; medical, surgical and rehabilitative management of spinal cord trauma; and some new approaches for improving recovery in patients, including restoration of function by electrical stimulation, locomotor training, and the use of robotics. Other chapters cover cell transplantation, artificial scaffolds, experimental pharmacological interventions, and molecular and combinatorial strategies for repairing the injured spinal cord. This volume should be of interest to neuroscience and clinical neurology research specialists and practicing neurologists. Comprehensive coverage of the latest scientific understanding of spinal cord injuries Detailed coverage of current treatment best practices and potential future treatments Connects leading edge research programs to future treatment opportunities

Neurorestoratology

Neurorestoratology
Author: Hongyun Huang
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2015
Genre: Nervous system
ISBN: 9781634636001
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Neurorestoratology is one of the most important disciplines in modern medicine and is also the most important discipline in neuroscience. Its core aim is to restore, promote and maintain the integrity of impaired or lost neuronal functions and/or structures by using novel cell-based comprehensive neurorestorative strategies. This book is the first and a unique one that systematically expounds the main aspects of neurorestoratology, which includes three sections with 22 chapters in two volumes. It systematically elaborates CNS neurorestorable theory and neurorestorative mechanisms. It firstly comprehends the Neurorestorative Process as a whole and Neurorestorative law. It fully describes all neurorestorative strategies and their continuing clinical progresses and achievements, especially the cell-based comprehensive neurorestorative strategies.

Spinal Cord Injury, An Issue of Physical Medicine and Rehabilitation Clinics of North America E-Book

Spinal Cord Injury, An Issue of Physical Medicine and Rehabilitation Clinics of North America E-Book
Author: John L. Lin
Publisher: Elsevier Health Sciences
Total Pages: 233
Release: 2020-07-31
Genre: Medical
ISBN: 0323756409
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This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Drs. John L. Lin, will discuss a number of important topics around Spinal Cord Injury. This issue of one of four issues selected each year by series Consulting Editor, Santos Martinez. Topics discussed in this issue include, but are not limited to: Updates for the International Standards for Neurological Classification of Spinal Cord Injury, Approaching Prognosis for Recovery after SCI, Cognitive Dysfunction in Persons with Spinal Cord Injuries, Spinal Cord Injury Pain: updated for the 21st century, Pulmonary management in patients with spinal cord injury, Therapeutic interventions to improve mobility with spinal cord injury related upper motor neuron syndromes, Neurogenic bowel management using trans-anal irrigation by persons with spinal cord injury, Heterotopic Ossification: beyond etidronate, Orthopedic Surgical Management of Upper Extremity Dysfunctions in Pediatric Populations with Spinal Cord injury, and Vocational Rehab and employment after spinal cord injury, among others.

Management and Rehabilitation of Spinal Cord Injuries

Management and Rehabilitation of Spinal Cord Injuries
Author: Hyun-Yoon Ko
Publisher: Springer
Total Pages: 507
Release: 2019-07-30
Genre: Medical
ISBN: 9811070334
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This comprehensive, up-to-date guide to the rehabilitation care of persons with spinal cord injuries and disorders draws on the ever-expanding scientific and clinical evidence base to provide clinicians with all the knowledge needed in order to make optimal management decisions during the acute, subacute, and chronic phases. A wealth of information is presented on the diverse medical consequences and complications encountered in these patients and on the appropriate rehabilitative measures in each circumstance. The coverage encompasses all forms of spinal cord injury and all affected organ systems. Readers will also find chapters on the basics of functional anatomy, neurological classification and evaluation, injuries specifically in children and the elderly, and psychological issues. The book will be an invaluable aid to assessment and medical care for physicians and other professional personnel in multiple specialties, including physiatrists, neurosurgeons, orthopedic surgeons, internists, critical care physicians, urologists, neurologists, psychologists, and social workers.

Spinal Cord Injury

Spinal Cord Injury
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 360
Release: 2005-07-27
Genre: Medical
ISBN: 0309165202
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An estimated 11,000 spinal cord injuries occur each year in the United States and more than 200,000 Americans suffer from maladies associated with spinal cord injury. This includes paralysis, bowel and bladder dysfunction, sexual dysfunction, respiratory impairment, temperature regulation problems, and chronic pain. During the last two decades, longstanding beliefs about the inability of the adult central nervous system to heal itself have been eroded by the flood of new information from research in the neurosciences and related fields. However, there are still no cures and the challenge of restoring function in the wake of spinal cord injuries remains extremely complex. Spinal Cord Injury examines the future directions for research with the goal to accelerate the development of cures for spinal cord injuries. While many of the recommendations are framed within the context of the specific needs articulated by the New York Spinal Cord Injury Research Board, the Institute of Medicine's panel of experts looked very broadly at research priorities relating to future directions for the field in general and make recommendations to strengthen and coordinate the existing infrastructure. Funders at federal and state agencies, academic organizations, pharmaceutical and device companies, and non-profit organizations will all find this book to be an essential resource as they examine their opportunities.

Spinal Cord Injury Therapy

Spinal Cord Injury Therapy
Author: José Juan Antonio Ibarra Arias
Publisher: BoD – Books on Demand
Total Pages: 173
Release: 2019-11-27
Genre: Medical
ISBN: 1789841615
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Spinal cord injury (SCI) is one of the main pathologies causing significant loss of neurological function. Therefore, a variety of pharmacological and non-pharmacological therapies are the aims of several studies. To provide the best care, it is important to know and understand the therapeutic approaches that have shown important progress in this topic. This book contains eight chapters that are divided into three sections: Introduction, Pharmacological Therapies, and Non-Pharmacological Therapies. The authors of the chapters deal with the pathophysiology of SCI, the effect of antioxidant and immunosuppressive agents, stem cell-based therapies, the use of cultured cells for transference or transplantation, and the application of non-invasive modalities (transcutaneous electrical spinal cord stimulation, etc.) for SCI rehabilitation.

Handbook of Spinal Cord Injuries and Related Disorders

Handbook of Spinal Cord Injuries and Related Disorders
Author: Hyun-Yoon Ko
Publisher: Springer Nature
Total Pages: 561
Release: 2021-10-22
Genre: Medical
ISBN: 9811636796
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This easy-to-use handbook is designed to assist in the evaluation and management of spinal cord injuries and the diverse related disorders and conditions. Spinal cord injuries can cause abnormalities in all body systems due to dysfunction of the somatic motor and sensory systems and damage to the autonomic nerve system. The latter gives rise to respiratory and cardiac problems, temperature regulation disorders, endocrine system disorders, and many associated metabolic disorders. Other potential consequences of spinal cord injuries include pressure injuries and various disabilities and obstacles, ranging from physical limitations to social embarrassment. This handbook offers extensive guidance on medical management in different scenarios from the acute phase to long-term care, with a particular focus on information of importance for the solution of clinical problems commonly encountered in daily practice. It will be ideal for practitioners in rehabilitation medicine, neurosurgery, orthopedics, neurology, and other relevant specialties that deal with patients with spinal cord injuries.