Recent Advancement In Prodrugs
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| Author | : Kamal Shah |
| Publisher | : CRC Press |
| Total Pages | : 0 |
| Release | : 2020 |
| Genre | : Science |
| ISBN | : 9780429328275 |
Download Recent Advancement in Prodrugs Book in PDF, Epub and Kindle
Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
| Author | : Kamal Shah |
| Publisher | : CRC Press |
| Total Pages | : 350 |
| Release | : 2020-05-13 |
| Genre | : Science |
| ISBN | : 1000057976 |
Download Recent Advancement in Prodrugs Book in PDF, Epub and Kindle
Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.
| Author | : Claudiu Trandafir Supuran |
| Publisher | : Elsevier |
| Total Pages | : 0 |
| Release | : 2024-07-01 |
| Genre | : Science |
| ISBN | : 0443156344 |
Download Advances in Prodrugs Book in PDF, Epub and Kindle
Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools. Highlights chemistry and pharmacology-related aspects, offering a versatile tool for the readers involved in prodrug development and study Discusses in depth treatment of several activation mechanisms and applications for disease treatments Covers a range of topics from basic contents, design, mechanisms of actions to current applications in drugs
| Author | : Valentino Stella |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1447 |
| Release | : 2007-03-12 |
| Genre | : Medical |
| ISBN | : 038749782X |
Download Prodrugs Book in PDF, Epub and Kindle
These volumes represent a comprehensive guide to prodrugs. They guide the reader through the current status of the prodrug concept and its many applications and highlight its many successes in overcoming formulation and delivery of problematic drugs. Replete with examples of approved and marketed prodrugs, these volumes introduce the topic to the novice as well as professional in the design of prodrugs.
| Author | : Vivekkumar K Redasani |
| Publisher | : Academic Press |
| Total Pages | : 84 |
| Release | : 2015-07-07 |
| Genre | : Science |
| ISBN | : 0128035579 |
Download Prodrug Design Book in PDF, Epub and Kindle
Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference. Offers unique, detailed overview of Prodrug research and literature Provides detailed chemical structures Includes Prodrug listing by therapeutic area
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 559 |
| Release | : 2006-12-15 |
| Genre | : Science |
| ISBN | : 0080467415 |
Download Annual Reports in Medicinal Chemistry Book in PDF, Epub and Kindle
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market. Critical reviews of the previous year's literature in many topics of interest to medicinal chemists Highlights major developments in medicinal chemistry Includes a comprehensive set of cumulative indices to easily locate topics in all published volumes
| Author | : Shahid Ul-Islam |
| Publisher | : John Wiley & Sons |
| Total Pages | : 432 |
| Release | : 2020-07-08 |
| Genre | : Science |
| ISBN | : 1119640423 |
Download Advances in Metallodrugs Book in PDF, Epub and Kindle
This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.
| Author | : Zhenbo Xu |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 140 |
| Release | : 2017-11-29 |
| Genre | : Science |
| ISBN | : 9535136496 |
Download Solubility of Polysaccharides Book in PDF, Epub and Kindle
Sugars, with a scientific term as saccharides, are involved in various aspects in the lives of human beings, including the sense of taste, energy for daily life, etc. Recent development in polysaccharides, as well as the background knowledge in this field, further deepens insight into their roles as healthy supplements. In this book, the principles on polysaccharides' solubility and structure, methodologies and application of polysaccharides have been reviewed. The chapters in this book include the relationship between structure and solubility of polysaccharide, the experimental and computational researches on polysaccharide solubility and the common polysaccharide, which may further aid scholars and researchers in regard to solubility of polysaccharides, methodologies and modification.
| Author | : Padma V. Devarajan |
| Publisher | : Springer |
| Total Pages | : 788 |
| Release | : 2014-12-08 |
| Genre | : Medical |
| ISBN | : 3319113550 |
Download Targeted Drug Delivery : Concepts and Design Book in PDF, Epub and Kindle
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.
| Author | : Tommy Liljefors |
| Publisher | : CRC Press |
| Total Pages | : 596 |
| Release | : 2002-07-25 |
| Genre | : Medical |
| ISBN | : 9780415282888 |
Download Textbook of Drug Design and Discovery, Third Edition Book in PDF, Epub and Kindle
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.
