Proton Pump Inhibitors A Balanced View
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Author | : T. Chiba |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 130 |
Release | : 2013-09-23 |
Genre | : Medical |
ISBN | : 3318024163 |
Download Proton Pump Inhibitors: A Balanced View Book in PDF, Epub and Kindle
The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of enormous value in gastroenterology. The authors provide an update on a variety of subjects, starting with an introduction to the discovery and development of PPIs. This is followed by chapters on pharmacokinetics, pharmacodynamics and pharmacogenetics, gastroesophageal reflux disease, gastroprotection, Helicobacter pylori eradication treatment, peptic ulcer disease, functional dyspepsia, acid suppression in exocrine pancreatic insufficiency, and gastrointestinal and systemic side effects. Readers who are interested in a current overview of PPIs and their various applications will find this book of great value.
Author | : T. Chiba |
Publisher | : Karger Medical and Scientific Publishers |
Total Pages | : 130 |
Release | : 2013-09-23 |
Genre | : Medical |
ISBN | : 3318024155 |
Download Proton Pump Inhibitors: A Balanced View Book in PDF, Epub and Kindle
The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of enormous value in gastroenterology. The authors provide an update on a variety of subjects, starting with an introduction to the discovery and development of PPIs. This is followed by chapters on pharmacokinetics, pharmacodynamics and pharmacogenetics, gastroesophageal reflux disease, gastroprotection, Helicobacter pylori eradication treatment, peptic ulcer disease, functional dyspepsia, acid suppression in exocrine pancreatic insufficiency, and gastrointestinal and systemic side effects. Readers who are interested in a current overview of PPIs and their various applications will find this book of great value.
Author | : Lars Olbe |
Publisher | : Birkhäuser |
Total Pages | : 245 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3034887957 |
Download Proton Pump Inhibitors Book in PDF, Epub and Kindle
Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be tween efficacy and safety of a new drug. This goal often involves time and many different specialists.
Author | : Joel E. Richter |
Publisher | : John Wiley & Sons |
Total Pages | : 73 |
Release | : 2021-07-13 |
Genre | : Medical |
ISBN | : 1119599601 |
Download The Esophagus Book in PDF, Epub and Kindle
THE ESOPHAGUS The Esophagus investigates the anatomy, physiology, and pathology of the esophagus. This sixth edition, revised and updated throughout, also explores the diagnosis and treatment of various esophageal conditions. It includes treatment guidelines approved by the two largest gastroenterology societies, the ACG and AGA, as befits a work co-edited by two former presidents of those organizations. Advancements in diagnostics are presented, as are developments in the surgical and drug therapies. Presented in full colour, and boasting an unrivalled team of editors and contributing authors, The Esophagus Sixth Edition will find a home wherever the anatomy, physiology, and pathology of the esophagus are studied and taught. This book is accompanied by a website containing all the figures from the book in PowerPoint format. www.wiley.com/go/richter/esophagus6e Praise for the Fifth Edition: “There is absolutely no doubt that this edition of the textbook will maintain its status as the go-to reference for esophageal conditions, and will remain a highly utilized and clinically useful resource for novice and experienced physicians and surgeons alike.” (Gastroenterology, 1 July 2013)
Author | : Irvin M. Modlin |
Publisher | : Lippincott Williams & Wilkins |
Total Pages | : 556 |
Release | : 2004 |
Genre | : Medical |
ISBN | : 9780781741231 |
Download Acid Related Diseases Book in PDF, Epub and Kindle
This textbook explores the history, biology, and treatment of acid related diseases, including gastric and duodenal ulcer disease, gastroesophageal reflux disease (GERD), and the role of H. pylori. The text offers thorough coverage of the subject matter, with an in-depth historical and biological focus. Equal focus is given to the biology and pharmacology of acid secretion and to the specific disease states of ulcers and GERD. This edition is full of new full-color medical illustrations of all aspects of this topic.
Author | : Brian L. Erstad |
Publisher | : |
Total Pages | : 1120 |
Release | : 2016 |
Genre | : |
ISBN | : 9781939862204 |
Download Critical Care Pharmacotherapy Book in PDF, Epub and Kindle
Author | : Leslie Neal-Boylan |
Publisher | : John Wiley & Sons |
Total Pages | : 432 |
Release | : 2011-11-28 |
Genre | : Medical |
ISBN | : 1118277856 |
Download Clinical Case Studies for the Family Nurse Practitioner Book in PDF, Epub and Kindle
Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use.
Author | : Tracey Straker |
Publisher | : |
Total Pages | : 481 |
Release | : 2018-12-10 |
Genre | : Medical |
ISBN | : 0190850698 |
Download Anesthesiology: a Problem-Based Learning Approach Book in PDF, Epub and Kindle
Using illustrative clinical cases, this volume in the Problem-Based Learning series reviews key topics in Anesthesia frequently encountered in clinical practice and on examinations. It highlights practical issues that arise in the operating room and solutions for them. With real-world clinical cases and discussion questions that guide case progression, this book facilitates both individual and small-group learning. Each case is further broken down to include additional related subtopics for maximum yield. Evidence-based reviews and multiple-choice self-assessment questions follow each case, making this book ideal for continuing education in anesthesia for the generalist and specialist practitioner. Teachers and trainees in anesthesiology will take advantage of this book's features for targeted teaching, learning, and retention.
Author | : Michael F. Vaezi |
Publisher | : Springer |
Total Pages | : 165 |
Release | : 2015-07-21 |
Genre | : Medical |
ISBN | : 3319195247 |
Download Diagnosis and Treatment of Gastroesophageal Reflux Disease Book in PDF, Epub and Kindle
This volume presents the most recent developments in diagnosis and treatment of patients with gastroesophageal reflux disease (GERD) and those who continue to be refractory to conventional GERD therapies. The book delineates the role of newly developed endoscopic therapies in GERD and outlines the best candidates for surgical fundoplication. Topics as the risks associated with GERD, lifestyle modification in GERD and the role of H2RA and proton pump inhibitor therapy in treating reflux disease are also explored. Written by authorities in the field, Diagnosis and Treatment of Gastroesophageal Reflux Disease is a concise yet comprehensive resource that is useful for primary care providers, gastroenterologists, pulmonologists, surgeons and ENT specialists.
Author | : Jonathan Aviv, MD, FACS |
Publisher | : Harmony |
Total Pages | : 306 |
Release | : 2017-01-24 |
Genre | : Health & Fitness |
ISBN | : 110190559X |
Download The Acid Watcher Diet Book in PDF, Epub and Kindle
Dr. Aviv guides readers through healthy dietary choices with targeted recipes, helping them balance their bodies and minds for optimal health and break acid-generating habits for good. Do you suffer from abdominal bloating; a chronic, nagging cough or sore throat; postnasal drip; a feeling of a lump in the back of your throat; allergies; or shortness of breath? If so, odds are that you are experiencing acid reflux without recognizing its silent symptoms, which can lead to serious long-term health problems, including esophageal cancer. In The Acid Watcher Diet, Dr. Jonathan Aviv, a leading authority on the diagnosis and treatment of acid reflux disease, helps readers identify those often misunderstood symptoms while providing a proven solution for reducing whole-body acid damage quickly and easily. His 28-day program is part of a two-phase eating plan, with a healthy balance of both macronutrients (proteins, carbs, and fats) and micronutrients (vitamins, minerals, antioxidants), that works to immediately neutralize acid and relieve the inflammation at the root of acid reflux.