Principles of Heart Valve Engineering

Principles of Heart Valve Engineering
Author: Arash Kheradvar
Publisher: Academic Press
Total Pages: 414
Release: 2019-08-28
Genre: Science
ISBN: 0128146621
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Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. Covers the depth and breadth of this interdisciplinary area of research Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering Contains contributions from leading experts in the field that are heavily illustrated

The Mechanics of Transcatheter and Surgical Heart Valves

The Mechanics of Transcatheter and Surgical Heart Valves
Author: Lakshmi Prasad Dasi
Publisher: Academic Press
Total Pages: 0
Release: 2020-09-15
Genre: Science
ISBN: 9780128145548
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The Mechanics of Transcatheter and Surgical Heart Valves: A Guide for Engineers and Clinicians focuses on the fundamental principles of heart valve mechanics, providing a detailed picture of the pros and cons of current devices in the context of their biomechanics, biomaterials, patient complications, and their regulatory and fabrication aspects. The book covers methods and applications that will help readers innovate and design new cardiovascular technology. It is ideal for designers, testers and manufacturers, anyone working in the biomaterials industry on coatings or fabrication materials, or those researching mechanics and heart valve biology. Covers fluid mechanics, solid mechanics and biomaterials concepts Provides the only book on the market to offer this depth of information on prosthetic heart valves Includes flow visualization videos and high-speed valve imaging videos

The Aortic Valve

The Aortic Valve
Author: ManoJ. Thubrikar
Publisher: Routledge
Total Pages: 236
Release: 2018-05-04
Genre: Medical
ISBN: 1351411403
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This book provides information on the aortic valve. Written in a comprehensive style, it emphasizes the principles behind the development of artificial valves. It covers the principles of valve geometry, tissue structure and function relationships, valve dynamics, fluid dynamics, mechanical stresses, echocardiographic images, mechanisms of valve sounds, valvular pathology, and design and performance of bioprosthetic valves. It enhances our understanding of angiographic and echocardiographic images and calcific stenosis, and will be of value in the development of better prostheses. The Aortic Valve is the ideal text for biomedical engineers and a unique resource for teaching interdisciplinary approaches to medical and engineering students. This work is also an indispensible source for cardiac surgeons, pathologists, cardiologists, and manufacturers of prosthetic valves.

Heart Valves

Heart Valves
Author: Paul A. Iaizzo
Publisher: Springer Nature
Total Pages: 620
Release: 2023-06-08
Genre: Science
ISBN: 3031255410
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This state-of-the-art handbook is dedicated to cardiac valve anatomy, models for testing and research methods, clinical trials; and clinical needs and applications. In this new edition, chapters are updated with the latest research in addition to new chapters on complex repair of CHD requiring conduits, new trends for valve replacement like the Ozaki procedure, as well as complex procedures in TAV, SAV, HARPOON, and BASILICA, with case studies for each type of procedure. This volume serves as a helpful reference for patients, educators, students, device designers and developers, clinical study specialists, clinicians, and other associated healthcare providers.

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease
Author: Elena Aikawa
Publisher: BoD – Books on Demand
Total Pages: 544
Release: 2013-06-12
Genre: Medical
ISBN: 9535111507
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Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Aortic Valve

Aortic Valve
Author: Mano J. Thubrikar
Publisher: CRC-Press
Total Pages: 221
Release: 1989-11-30
Genre: Medical
ISBN: 9780849347719
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This book provides information on the aortic valve. Written in a comprehensive style, it emphasizes the principles behind the development of artificial valves. It covers the principles of valve geometry, tissue structure and function relationships, valve dynamics, fluid dynamics, mechanical stresses, echocardiographic images, mechanisms of valve sounds, valvular pathology, and design and performance of bioprosthetic valves. It enhances our understanding of angiographic and echocardiographic images and calcific stenosis, and will be of value in the development of better prostheses. The Aortic Valve is the ideal text for biomedical engineers and a unique resource for teaching interdisciplinary approaches to medical and engineering students. This work is also an indispensible source for cardiac surgeons, pathologists, cardiologists, and manufacturers of prosthetic valves.

Advances in Heart Valve Biomechanics

Advances in Heart Valve Biomechanics
Author: Michael S. Sacks
Publisher: Springer
Total Pages: 487
Release: 2019-04-08
Genre: Science
ISBN: 3030019934
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This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.

Animals and Medicine

Animals and Medicine
Author: Jack Botting
Publisher: Open Book Publishers
Total Pages: 246
Release: 2015-05-04
Genre: Medical
ISBN: 1783741171
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Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Cardiac Tissue Engineering

Cardiac Tissue Engineering
Author: Smadar Cohen
Publisher: Morgan & Claypool Publishers
Total Pages: 202
Release: 2012-10-01
Genre: Technology & Engineering
ISBN: 1608452050
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Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart: Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials: Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration

Cardiovascular Disability

Cardiovascular Disability
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 304
Release: 2010-12-04
Genre: Medical
ISBN: 030915698X
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The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.