Textbook of Pancreatic Cancer

Textbook of Pancreatic Cancer
Author: Kjetil Søreide
Publisher: Springer Nature
Total Pages: 1320
Release: 2021-02-04
Genre: Medical
ISBN: 3030537862

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This textbook provides a practically applicable resource for understanding the surgical oncology management of pancreatic cancer. It discusses relevant aspects of anatomy and pathophysiology along with the latest diagnostic techniques. Insightful descriptions are then provided detailing how to perform critical surgical procedures when treating these patients. Relevant perioperative management strategies and emerging themes in cancer biology critical to understanding and treating the disease are also described. The need for cross-discipline collaboration to facilitate and enhance innovation within the discipline is reinforced throughout the text. Each chapter presents the relevant current clinical standards along with areas of controversy in both research and clinical practice within “pearls and pitfalls” sections. Textbook of Pancreatic Cancer: Principles and Practice of Surgical Oncology is a detailed work covering the basic material important to trainees as well as advanced curriculum for established specialists in the field from a multi-disciplinary perspective. Therefore, it is crucial resource for all practicing and trainee professionals who encounter these patients in their day-to-day clinical practice.

Pancreatic Cancer

Pancreatic Cancer
Author: Douglas B. Evans
Publisher: Springer Science & Business Media
Total Pages: 413
Release: 2006-04-18
Genre: Medical
ISBN: 0387216006

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The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.

Pancreatic Cancer

Pancreatic Cancer
Author: Michael J. Lippe
Publisher: JHU Press
Total Pages: 185
Release: 2011-06-15
Genre: Health & Fitness
ISBN: 1421402556

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Michael J. Lippe was diagnosed with pancreatic cancer in 2007. This is his story, and the story of pancreatic cancer, narrated by Lippe and Dr. Dung T. Le, the physician who is treating him. In telling these stories, Lippe and Le alternate chapters. Lippe writes about the early signs that something was wrong; Le continues with a description of pancreatic cancer, its symptoms, and its treatments. Lippe talks about his prognosis, contemplates the prospect of death, and describes how he began to cope; Le explains the importance, for both doctor and patient, of balancing hope and truth. Lippe speaks frankly about the toll the disease takes on his marriage and family; Le offers a general picture of what most patients can expect with their illness. The book concludes with Lippe and Le’s reflections on their partnership in treating cancer, lessons they have learned, and their thoughts about the positive things that sometimes emerge from illness. Pancreatic Cancer offers clear explanations of what the disease is, describes what people with the disease will feel physically and mentally, and discusses current treatments and future directions of research. The authors hope that their honest yet hopeful perspective will help all people with cancer and those who care about them.

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism
Author: Anne Le
Publisher: Springer
Total Pages: 186
Release: 2018-06-26
Genre: Medical
ISBN: 331977736X

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Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

100 Questions & Answers About Pancreatic Cancer

100 Questions & Answers About Pancreatic Cancer
Author: Eileen O'Reilly
Publisher: Jones & Bartlett Publishers
Total Pages: 258
Release: 2010-10-25
Genre: Health & Fitness
ISBN: 1449611028

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Whether you’re a newly diagnosed pancreatic cancer patient, a survivor, or a friend or relative of someone with pancreatic cancer, this book offers help. The only text to provide a doctor’s and patient’s view, 100 Questions & Answers About Pancreatic Cancer, Second Edition gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of support, and much more. The authors, a medical oncologist and a nurse with 25 years of experience with cancer patients, provide a comprehensive, step-by-step discussion of what you can expect in the diagnosis and treatment of pancreatic cancer, while patient commentaries provide a real-life understanding of what these steps might mean for your day-to-day life. This book is an invaluable resource for anyone coping with the physical and emotional turmoil of this disease.

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy
Author: Ganji Purnachandra Nagaraju
Publisher: Academic Press
Total Pages: 223
Release: 2019-02-26
Genre: Science
ISBN: 0128176628

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Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy. Modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property by introducing new strategies and drugs Provides information about on-going research as well as clinical data on pancreatic cancer and detailed descriptions about therapeutic options for easy understanding Utilizes full color figures to help the understanding of the content and tables for easy comparison of information as well as quick access to it

Surgical Atlas of Pancreatic Cancer

Surgical Atlas of Pancreatic Cancer
Author: Ying-bin Liu
Publisher: Springer Nature
Total Pages: 225
Release: 2019-11-01
Genre: Medical
ISBN: 9813298642

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This book comprehensively discusses advanced surgical techniques for pancreatic cancers, including open, laparoscopic and robotic-assisted surgery, as well as palliative surgery and total meso-pancreas excision. It also features high-resolution illustrations taken from selected clinical cases to enhance the descriptions of the surgical procedures. Providing details of technical issues and commenting on the outcome, it a timely reference resource for pancreatic surgeons, pancreatic physicians, and interns interested in pancreatic cancer surgery.

Surviving Pancreatic Cancer

Surviving Pancreatic Cancer
Author: Larisa Belote
Publisher: Step by Step - Wellness
Total Pages: 100
Release: 2015-04-13
Genre:
ISBN: 9780996266208

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Surviving Pancreatic Cancer is a story about a 54 year old woman who was given a death sentence of 3 months to live based on the diagnosis. Against all odds, she conquers the disease by going through the most innovative treatment, dietary supplementation and proper nutrition. Empower yourself with knowledge about effective alternative/holistic cancer treatments that are available and make an educated decision rather than surrender to the traditional treatments of chemotherapy, radiation and even surgery that offer little hope. Innovative and alternative treatments may prolong your life, not only to exist, but to live a good quality of life with your loved ones. You will also find a guide that outlines steps to healing your body and building a strong immune system. Great for people who have cancer, recovering or just want to be proactive.

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer
Author: Asfar Azmi
Publisher: Academic Press
Total Pages: 458
Release: 2018-11-13
Genre: Medical
ISBN: 9780128103241

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Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas - helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Clinical Pancreatology for Practising Gastroenterologists and Surgeons

Clinical Pancreatology for Practising Gastroenterologists and Surgeons
Author: Juan Enrique Dominguez-Munoz
Publisher: John Wiley & Sons
Total Pages: 752
Release: 2021-03-17
Genre: Medical
ISBN: 111957014X

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Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.