Organic Reactions in Steroid Chemistry
Author | : John Fried |
Publisher | : |
Total Pages | : 528 |
Release | : 1972 |
Genre | : Medical |
ISBN | : |
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Author | : John Fried |
Publisher | : |
Total Pages | : 528 |
Release | : 1972 |
Genre | : Medical |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 464 |
Release | : 1972 |
Genre | : |
ISBN | : |
Author | : J. R. Hanson |
Publisher | : Elsevier |
Total Pages | : 113 |
Release | : 2016-06-23 |
Genre | : Science |
ISBN | : 148313928X |
Introduction to Steroid Chemistry is a six-chapter introductory text of the analysis, conformation, and production of steroids. After providing a brief overview of steroid chemistry, this book goes on discussing the application of physical methods to the analysis of structural and stereochemical correlations in steroids, such as UV, infrared, NMR, and mass spectroscopy, optical rotary dispersion, and circular dichroism. The subsequent two chapters describe the influence of steroid conformation and molecular rearrangements on reactions rates and reaction products. The remaining chapters explore the improvements in the synthesis of the estrogenic hormones and the biosynthetic pathways and metabolism of cholesterol. This book will be of value to general and organic chemists, biochemists, and research workers in related subjects.
Author | : John Fried |
Publisher | : |
Total Pages | : |
Release | : 1972 |
Genre | : |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 464 |
Release | : 1972 |
Genre | : Chemistry, Organic |
ISBN | : |
Author | : John Fried |
Publisher | : |
Total Pages | : 0 |
Release | : 1972 |
Genre | : Organic compounds |
ISBN | : |
Author | : Daniel Lednicer |
Publisher | : John Wiley & Sons |
Total Pages | : 154 |
Release | : 2011-06-20 |
Genre | : Science |
ISBN | : 111995729X |
The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.
Author | : Charles W. Shoppee |
Publisher | : |
Total Pages | : 332 |
Release | : 1958 |
Genre | : Steroids |
ISBN | : |
Author | : Carl Djerassi |
Publisher | : |
Total Pages | : 680 |
Release | : 1963 |
Genre | : Science |
ISBN | : |
Author | : Robert T. Blickenstaff |
Publisher | : Academic Press |
Total Pages | : 345 |
Release | : 2013-10-22 |
Genre | : Science |
ISBN | : 148321642X |
Organic Chemistry, Volume 30: Total Synthesis of Steroids provides an overall view of steroid total synthesis, including the general approaches, special problems, stereochemical complexities, expansion or contraction of rings, and insertion of hetero atoms. The book discusses the process of designing total syntheses; the biogenetic-like steroid synthesis, including cyclization of terminal epoxides as well as the total synthesis from nonepoxide precursors; and the synthesis of equilenin, estrone, bisdehydrodoisynolic acid, 18,19-bisnorprogesterone, 19-norpregnanes, and heterocyclic steroids. The text also describes the application of ABD intermediates in the Torgov synthesis; the synthesis of carbocyclics and thiasteroids; and the synthesis from p-anisylcyclohexanes and from C-5, C-8 bridged intermediates. The synthesis based on the type of reaction used in the condensation of the A fragment with the CD portion, as well as the methods of total synthesis in the preparation of 8-azasteroids and 8,13-diazasteroids are also considered. The book further tackles the synthesis of epiandrosterone, cortisone, aldosterone, 3ß-hydroxy-5a-pregnan-20-one, latifoline, conessine, and ring C aromatic steroids; the synthesis of trans-benzohydrindane derivatives and other common derivatives; and the synthesis of CD intermediates. Chemists, biochemists, and people involved in the study of steroid total syntheses will find the book invaluable.