Interventional Cardiac Electrophysiology

Interventional Cardiac Electrophysiology
Author: Ralph J. Damiano, Jr., MD, FACC, FACS
Publisher: Cardiotext Publishing
Total Pages: 1046
Release: 2015-05-15
Genre: Medical
ISBN: 193539584X

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Interventional Cardiac Electrophysiology is the first and only comprehensive, state-of-the-art textbook written for practitioners in multiple specialties involved in the care of the arrhythmia patient. Encompassing the entire field of interventional therapy for cardiac rhythm management, from basic science to evidence-based medicine to future directions, topics include: Technology and Therapeutic Techniques – EP techniques; imaging and radiologic technology; device and ablation technology; drug therapy.Interventional Electrophysiologic Procedures – Diagnostic and physiologic EP techniques; mapping in percutaneous catheter and surgical EP procedures; catheter and surgical ablation; device implantation and management.Clinical Indications and Evidence-based Outcomes Standards – For medical and surgical EP interventions for arrhythmias.New Directions in Interventional Electrophysiology – Hybrid therapy for atrial and ventricular arrhythmias and staged therapy. This book will be essential reading for clinicians and researchers that form the health care team for arrhythmia patients: cardiologists, adult and pediatric clinical electrophysiologists, interventional electrophysiologists, cardiac surgeons practicing arrhythmia surgery, allied health care professionals, pharmacologists, radiologists and anesthesiologists evaluating arrhythmia patients, and basic scientists from the biomedical engineering and experimental physiology disciplines. Professor Sanjeev Saksena has been involved in this arena for over three decades and has brought his experience to this textbook, assembling editorial leadership from medical and surgical cardiology to provide a global perspective on fundamentals of medical practice, evidence-based therapeutic practices, and emerging research in this field. This book includes 95 videos.

Essential Cardiac Electrophysiology

Essential Cardiac Electrophysiology
Author: Zainul Abedin
Publisher: John Wiley & Sons
Total Pages: 497
Release: 2013-02-01
Genre: Medical
ISBN: 1118522028

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This new edition of Essential Cardiac Electrophysiology: The Self-Assessment Approach continues the successful formula of the first edition, providing a concise and thorough overview of Electrophysiology supplemented by challenging questions readers can use to test their knowledge and prepare for examinations. Comprehensively updated and significantly expanded to include the latest recommendations, findings from leading-edge research, emergent diagnostic tools, and new therapeutic options, Essential Cardiac Electrophysiology: The Self-Assessment Approach now offers coverage of some of hottest topics in EP, including: HCN channels; Congenital, and paroxysmal AV blocks; Left atrial flutter; Electrophysiologic assessment of AVNRT and AVRT; VT ablation; Short QT syndrome; Early repolarization and ventricular fibrillation; Aortic cusp VT; Commotio Cordis, and more. Fact-based and clinically-focused, Essential Cardiac Electrophysiology: The Self-Assessment Approach is an ideal reference for all members of the EP care team, from cardiac care nurses and technicians to EP and cardiology fellows to practicing electrophysiologists. Packed with questions designed to aid readers’ understanding of key concepts and retention of essential facts, it is an excellent study aid for those preparing for board examination or other EP certifications.

Recent Advances and Current Limitations of Available Technology to Optically Manipulate and Observe Cardiac Electrophysiology

Recent Advances and Current Limitations of Available Technology to Optically Manipulate and Observe Cardiac Electrophysiology
Author: Gerard A. Marchal
Publisher:
Total Pages: 0
Release: 2023
Genre:
ISBN:

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Abstract: Optogenetics, utilising light-reactive proteins to manipulate tissue activity, are a relatively novel approach in the field of cardiac electrophysiology. We here provide an overview of light-activated transmembrane channels (optogenetic actuators) currently applied in strategies to modulate cardiac activity, as well as newly developed variants yet to be implemented in the heart. In addition, we touch upon genetically encoded indicators (optogenetic sensors) and fluorescent dyes to monitor tissue activity, including cardiac transmembrane potential and ion homeostasis. The combination of the two allows for all-optical approaches to monitor and manipulate the heart without any physical contact. However, spectral congestion poses a major obstacle, arising due to the overlap of excitation/activation and emission spectra of various optogenetic proteins and/or fluorescent dyes, resulting in optical crosstalk. Therefore, optogenetic proteins and fluorescent dyes should be carefully selected to avoid optical crosstalk and consequent disruptions in readouts and/or cellular activity. We here present a novel approach to simultaneously monitor transmembrane potential and cytosolic calcium, while also performing optogenetic manipulation. For this, we used the novel voltage-sensitive dye ElectroFluor 730p and the cytosolic calcium indicator X-Rhod-1 in mouse hearts expressing channelrhodopsin-2 (ChR2). By exploiting the isosbestic point of ElectroFluor 730p and avoiding the ChR2 activation spectrum, we here introduce a novel optical imaging and manipulation approach with minimal crosstalk. Future developments in both optogenetic proteins and fluorescent dyes will allow for additional and more optimised strategies, promising a bright future for all-optical approaches in the field of cardiac electrophysiology

Cardiac Optogenetics: Using Light to Observe and Excite the Heart

Cardiac Optogenetics: Using Light to Observe and Excite the Heart
Author: Tobias Bruegmann
Publisher: Frontiers Media SA
Total Pages: 189
Release: 2022-11-15
Genre: Science
ISBN: 2832505821

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Topic Editor Godfrey Smith is the founder, director and honorary Chief Scientific Officer of Clyde Biosciences Ltd (UK). The other Topic Editors declare no competing interests with regard to the Research Topic subject.

Essential Cardiac Electrophysiology: The Self-Assessment Approach, Third Edition

Essential Cardiac Electrophysiology: The Self-Assessment Approach, Third Edition
Author: Zainul Abedin, MD
Publisher: Cardiotext Publishing
Total Pages: 870
Release: 2020-03-01
Genre: Medical
ISBN: 1942909373

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“This book will be instantly enjoyed by electrophysiologists at all career stages as it communicates highly relevant information and provides an ‘instant check’ of one’s knowledge base.” ~From the foreword by Kalyanam Shivkumar, MD, PhD, FHRS, FRCP (Lond-Hon) Fact-based and clinically-focused, this new third edition of Essential Cardiac Electrophysiology: The Self-Assessment Approach is an ideal reference in a bullet-point format that provides a concise and essential overview of electrophysiology. Packed with ABIM-style 200 multiple-choice questions designed to aid readers' understanding of key concepts and retention of essential facts, it is an excellent study aid for electrophysiology fellows, cardiology fellows, and electrophysiologists preparing for board examination or other EP certifications. Comprehensively updated with the latest recommendations and findings, it includes multiple tables, electrophysiology tracings and illustrations, and a treasury of electrophysiology pearls. This expanded Third Edition includes new chapters on AV blocks, channelopathies, and ventricular arrhythmias in a structurally normal heart, along with enhanced coverage of: · Electrophysiologic aspects of AVNRT and AVRT · Long and short RP tachycardia · Parahisian pacing · Bystander activation of accessory pathways · Brugada syndrome · Long QT syndrome and pregnancy A note on the questions: All the questions are ABIM style. Some of the questions have a tangential approach, i.e., not only one has to know the correct diagnosis but also has to know the correct management approach. Some questions are "concept" questions; i.e., it is to evaluate a basic concept to verify understanding.

Basic Electrophysiological Methods

Basic Electrophysiological Methods
Author: Ellen Covey
Publisher: Oxford University Press
Total Pages: 241
Release: 2015-02-25
Genre: Medical
ISBN: 0199342547

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Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.

Cardiac Electrophysiology: From Cell to Bedside E-Book

Cardiac Electrophysiology: From Cell to Bedside E-Book
Author: Douglas P. Zipes
Publisher: Elsevier Health Sciences
Total Pages: 1397
Release: 2013-10-11
Genre: Medical
ISBN: 1455770108

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Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world. Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more! Integrate the latest scientific understanding of arrhythmias with the newest clinical applications, to select the right treatment and management options for each patient. Stay current on the latest advancements and developments with sweeping updates and 52 NEW chapters - written by many new authors - on some of the hottest cardiology topics, such as new technologies for the study of the molecular structure of ion channels, molecular genetics, and the development of new imaging, mapping and ablation techniques. Get expert advice from Dr. Douglas P. Zipes - a leading authority in electrophysiology and editor of Braunwald’s Heart Disease and the Heart Rhythm Journal - and Dr. Jose Jalife - a world-renowned leader and researcher in basic and translational cardiac electrophysiology. Access the full text online at Expert Consult, including supplemental text, figures, tables, and video clips.

Cardiac Electrophysiology: from Cell to Bedside

Cardiac Electrophysiology: from Cell to Bedside
Author: Douglas P. Zipes
Publisher: Elsevier Health Sciences
Total Pages: 1395
Release: 2013-10-25
Genre: Medical
ISBN: 145572856X

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Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world. Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more! Integrate the latest scientific understanding of arrhythmias with the newest clinical applications, to select the right treatment and management options for each patient. Stay current on the latest advancements and developments with sweeping updates and 52 NEW chapters - written by many new authors - on some of the hottest cardiology topics, such as new technologies for the study of the molecular structure of ion channels, molecular genetics, and the development of new imaging, mapping and ablation techniques. Get expert advice from Dr. Douglas P. Zipes - a leading authority in electrophysiology and editor of Braunwald's Heart Disease and the Heart Rhythm Journal - and Dr. Jose Jalife - a world-renowned leader and researcher in basic and translational cardiac electrophysiology. Access the full text online at Expert Consult, including supplemental text, figures, tables, and video clips. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.