Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 424 Neurotoxicity Study In Rodents
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Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 15 |
Release | : 1997-07-21 |
Genre | : |
ISBN | : 9264071024 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents Book in PDF, Epub and Kindle
This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 26 |
Release | : 2007-10-15 |
Genre | : |
ISBN | : 9264067396 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study Book in PDF, Epub and Kindle
A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 13 |
Release | : 2008-10-16 |
Genre | : |
ISBN | : 9264070680 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 7 |
Release | : 1995-07-27 |
Genre | : |
ISBN | : 9264070923 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 419: Delayed Neurotoxicity of Organophosphorus Substances: 28-day Repeated Dose Study Book in PDF, Epub and Kindle
This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 16 |
Release | : 2018-06-27 |
Genre | : |
ISBN | : 9264070702 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 18 |
Release | : 2018-06-27 |
Genre | : |
ISBN | : 9264071202 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies Book in PDF, Epub and Kindle
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 8 |
Release | : 1995-07-27 |
Genre | : |
ISBN | : 9264070907 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 418: Delayed Neurotoxicity of Organophosphorus Substances Following Acute Exposure Book in PDF, Epub and Kindle
The test substance is administered orally in a single dose to domestic hens. The animals are observed for 21 days, then the remainder of the hens are killed and histopathological examination is undertaken. The young adult domestic laying hen (Gallus ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 9 |
Release | : 1998-09-21 |
Genre | : |
ISBN | : 9264070729 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 14 |
Release | : 2018-06-27 |
Genre | : |
ISBN | : 9264070826 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study Book in PDF, Epub and Kindle
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 14 |
Release | : 2002-02-08 |
Genre | : |
ISBN | : 926407094X |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure Book in PDF, Epub and Kindle
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...