Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 408 Repeated Dose 90 Day Oral Toxicity Study In Rodents
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Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 16 |
Release | : 2018-06-27 |
Genre | : |
ISBN | : 9264070702 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 9 |
Release | : 1998-09-21 |
Genre | : |
ISBN | : 9264070729 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 13 |
Release | : 2008-10-16 |
Genre | : |
ISBN | : 9264070680 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents Book in PDF, Epub and Kindle
This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...
Author | : Organisation for Economic Co-operation and Development |
Publisher | : Organisation for Economic Co-operation and Development ; [Montréal : Renouf] |
Total Pages | : |
Release | : 1981 |
Genre | : Chemical industry |
ISBN | : 9789264122215 |
Download OECD Guidelines for Testing of Chemicals Book in PDF, Epub and Kindle
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 18 |
Release | : 2018-06-27 |
Genre | : |
ISBN | : 9264071202 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies Book in PDF, Epub and Kindle
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 15 |
Release | : 1997-07-21 |
Genre | : |
ISBN | : 9264071024 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents Book in PDF, Epub and Kindle
This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 14 |
Release | : 2002-02-08 |
Genre | : |
ISBN | : 926407094X |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure Book in PDF, Epub and Kindle
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 14 |
Release | : 2002-02-08 |
Genre | : |
ISBN | : 9264071008 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 423: Acute Oral toxicity - Acute Toxic Class Method Book in PDF, Epub and Kindle
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 37 |
Release | : 2022-06-30 |
Genre | : |
ISBN | : 9264366067 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay Book in PDF, Epub and Kindle
This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing mutagenicity because physiological factors, such as absorption of the test chemical from the site of exposure, distribution of the test chemical throughout the test system via systemic circulation, and in vivo metabolism and DNA repair processes, all contribute to the mutagenic responses.
Author | : OECD |
Publisher | : OECD Publishing |
Total Pages | : 9 |
Release | : 1981-05-12 |
Genre | : |
ISBN | : 9264070761 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study Book in PDF, Epub and Kindle
This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...