New Therapeutics for Traumatic Brain Injury

New Therapeutics for Traumatic Brain Injury
Author: Kim Heidenreich
Publisher: Academic Press
Total Pages: 354
Release: 2016-09-27
Genre: Psychology
ISBN: 0128027010
GET BOOK

Download New Therapeutics for Traumatic Brain Injury Book in PDF, Epub and Kindle

New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 412
Release: 2015-12-01
Genre: Medical
ISBN: 1498766579
GET BOOK

Download Translational Research in Traumatic Brain Injury Book in PDF, Epub and Kindle

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Traumatic Brain Injury

Traumatic Brain Injury
Author: Jack W. Tsao
Publisher: Springer Science & Business Media
Total Pages: 345
Release: 2012-06-13
Genre: Medical
ISBN: 0387878874
GET BOOK

Download Traumatic Brain Injury Book in PDF, Epub and Kindle

Traumatic brain injury (TBI) is a major cause of disability worldwide. Each year 1.7 million new TBIs occur in the United States, and it is also considered a signature injury of the Iraq and Afghanistan conflicts. Despite the relatively high incidence-within both civilian and military populations-the diagnosis and treatment, particularly of mild TBI/concussion, remains an inexact science. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation is a concise guide designed for neurologists, primary care, and sports physicians and other medical providers, psychologists and neuropsychologists, and athletic trainers who may evaluate and care for patients with TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies. A superb contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation offers a well-designed, well-written, useful resource for all providers who treat patients with TBI.

Brain Injury Medicine, Third Edition

Brain Injury Medicine, Third Edition
Author: Nathan D. Zasler, MD
Publisher: Springer Publishing Company
Total Pages: 1891
Release: 2021-09-01
Genre: Medical
ISBN: 0826143059
GET BOOK

Download Brain Injury Medicine, Third Edition Book in PDF, Epub and Kindle

“This updated textbook was much needed as there has been increased attention in recent years toward brain injuries. The book provides updated guidelines and clinical practice recommendations that support the intended audience of trainees and current practitioners. This update makes it the current standard text for any brain injury specialist." ---Doody's Review Service, 4 stars This revised and greatly expanded Third Edition of Brain Injury Medicine continues its reputation as the key core textbook in the field, bringing together evidence-based medicine and years of collective author clinical experience in a clear and comprehensive guide for brain injury professionals. Universally praised as the gold standard text and go-to clinical reference, the book covers the entire continuum of care from early diagnosis and assessment through acute management, rehabilitation, associated medical and quality of life issues, and functional outcomes. With 12 new chapters and expanded coverage in key areas of pathobiology and neuro-recovery, special populations, sport concussion, disorders of consciousness, neuropharmacology, and more, this "state of the science" resource promotes a multi-disciplinary approach to a complex condition with consideration of emerging topics and the latest clinical advances. Written by over 200 experts from all involved disciplines, the text runs the full gamut of practice of brain injury medicine including principles of public health and research, biomechanics and neural recovery, neuroimaging and neurodiagnostic testing, sport and military, prognosis and outcome, acute care, treatment of special populations, neurologic and other medical complications post-injury, motor and musculoskeletal problems, post-trauma pain disorders, cognitive and behavioral problems, functional mobility, neuropharmacology and alternative treatments, community reentry, and medicolegal and ethical issues. Unique in its scope of topics relevant to professionals working with patients with brain injury, this third edition offers the most complete and contemporary review of clinical practice standards in the field. Key Features: Thoroughly revised and updated Third Edition of the seminal reference on brain injury medicine Evidence-based consideration of emerging topics with new chapters covering pathobiology, biomarkers, neurorehabilitation nursing, neurodegenerative dementias, anoxic/hypoxic ischemic brain injury, infectious causes of acquired brain injury, neuropsychiatric assessment, PTSD, and capacity assessment Multi-disciplinary authorship with leading experts from a wide range of specialties including but not limited to physiatry, neurology, psychiatry, neurosurgery, neuropsychology, physical therapy, occupational therapy speech language pathology, and nursing New online chapters on survivorship, family perspectives, and resources for persons with brain injury and their caregivers Purchase includes digital access for use on most mobile devices or computers

Traumatic Brain Injury

Traumatic Brain Injury
Author: Jack W. Tsao
Publisher: Springer Nature
Total Pages: 465
Release: 2019-11-19
Genre: Medical
ISBN: 3030224368
GET BOOK

Download Traumatic Brain Injury Book in PDF, Epub and Kindle

This thoroughly revised and updated work covers numerous advances in traumatic brain injury diagnosis, evaluation, treatment, and pathophysiology. Since publication of the first edition in 2012, there has been greatly increased public awareness of the clinical consequences of even the mildest of head injuries, and the result has been a concerted effort of countries around the world to increase research funding. This second edition continues to focus on mild traumatic brain injury--or concussion--and contains updates to all the original chapters as well as adding new chapters addressing clinical sequelae, including pediatric concussion, visual changes, chronic traumatic encephalopathy, and blast-associated TBI. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, is a comprehensive resource designed for neurologists, primary care clinicians, sports physicians, and other medical providers, including psychologists and neuropsychologists, as well as athletic trainers who may evaluate and care for individuals who have sustained a TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies, and an updated appendix of ICD codes is included. An outstanding contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, again offers an invaluable resource for all providers who treat patients with TBI.

New Hope for Concussions TBI and PTSD

New Hope for Concussions TBI and PTSD
Author: Dr. Lawrence D. Komer
Publisher: Lulu.com
Total Pages: 232
Release: 2018-01-26
Genre: Science
ISBN: 099525012X
GET BOOK

Download New Hope for Concussions TBI and PTSD Book in PDF, Epub and Kindle

If you or someone you love has had a concussion or traumatic brain injury, this book is for you. "New Hope for Concussions TBI & PTSD" is a powerful resource for the injured, the caregivers, the sporting world, the medical community, and those serving our veterans and others with PTSD. It is a book of hope for all those who have been told, "We are sorry but there is nothing more we can do."

Cognitive Rehabilitation Therapy for Traumatic Brain Injury

Cognitive Rehabilitation Therapy for Traumatic Brain Injury
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 71
Release: 2013-03-25
Genre: Medical
ISBN: 0309267897
GET BOOK

Download Cognitive Rehabilitation Therapy for Traumatic Brain Injury Book in PDF, Epub and Kindle

In October 2011, the Institute of Medicine (IOM) released the report Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence, assessing the published evidence for the effectiveness of using cognitive rehabilitation therapy (CRT) to treat people with traumatic brain injury (TBI). TBI has gained increasing attention in the past 15 years because of its status as the signature wound of American military conflicts in Iraq and Afghanistan. Growing numbers of U.S. service members are suffering traumatic brain injuries and are surviving them, given that (a) the majority of traumatic brain injuries are mild and (b) lifesaving measures for more severe injuries have significantly improved. People with any level of injury can require ongoing health care in their recovery, helping them to regain (or compensate for) their losses of function and supporting their full integration into their social structure and an improved quality of life. One form of treatment for TBI is CRT, a systematic, goal-oriented approach to helping patients overcome cognitive impairments. The Department of Defense (DoD) asked the IOM to evaluate CRT for traumatic brain injury in order to guide the DoD's use and coverage in the Military Health System. Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence was the IOM's resulting study of the evidence. The report's conclusions revolved around the fact that there is little continuity among research studies of the effectiveness of different types of CRT, and there exist only small amounts of evidence (or, in many cases, none) demonstrating the effectiveness of using CRT to treat TBI-although the evidence that does exist generally indicates that CRT interventions have some effectiveness. The workshop brought together experts in health services administration, research, and clinical practice from the civilian and military arenas in order to discuss the barriers for evaluating the effectiveness of CRT care and for identifying suggested taxonomy, terminology, timing, and ways forward for CRT researchers. The workshop consisted of individuals and was not intended to constitute a comprehensive group. Select decision makers in the Military Health System and Veterans Affairs (VA) and researchers were invited to participate. The workshop was designed to spur thinking about (1) the types of research necessary to move the field forward toward evidence-based clinical guidelines, (2) what the translational pipeline looks like and what its current deficiencies are, and (3) considerations that decision makers may choose to use as they decide what research they will support and decide how they will balance the urgency of the need with the level of evidence for CRT interventions. Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Model Study Protocols and Frameworks to Advance the State of the Science summarizes the happenings of the workshop.

Interpretation of Bloodstain Evidence at Crime Scenes, Second Edition

Interpretation of Bloodstain Evidence at Crime Scenes, Second Edition
Author: William G. Eckert
Publisher: CRC Press
Total Pages: 820
Release: 1998-07-14
Genre: Law
ISBN: 9780849313622
GET BOOK

Download Interpretation of Bloodstain Evidence at Crime Scenes, Second Edition Book in PDF, Epub and Kindle

As witnessed in landmark criminal cases, the quality and integrity of bloodstain evidence can be a crucial factor in determining a verdict. Since the first edition of Interpretation of Bloodstain Evidence at Crime Scenes was published nearly a decade ago, bloodstain pattern interpretation has continued to grow as a branch of forensic science. Revised and updated to reflect new technology and developments in the field, the second edition is packed with new information and illustrations-including 421 photographs and diagrams of improved quality that will aid in interpretation of evidence. Expanding on a single chapter presented in the bestselling first edition, the second edition details, in four chapters, an introduction to bloodstain interpretation; low-velocity impact and angular considerations; medium and high-velocity impact; and the significance of partially dried, clotted, aged, and physically altered bloodstains in four new chapters. A full chapter on the detection of blood with luminol, featuring high-quality, full-color photographs of luminol reactions, has been added. This new edition also includes 12 new case studies in addition to 8 original case studies from the first edition that have been retained for their interpretative value. Everyone involved in crime scene evaluation and interpretation-law enforcement officers, criminologists, medical examiners, forensic pathologists, medicolegal personnel, and prosecutors and defense attorneys-will benefit from the improved and expanded second edition of this definitive reference.

Cognitive Rehabilitation Therapy for Traumatic Brain Injury

Cognitive Rehabilitation Therapy for Traumatic Brain Injury
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 71
Release: 2013-04-25
Genre: Medical
ISBN: 0309267862
GET BOOK

Download Cognitive Rehabilitation Therapy for Traumatic Brain Injury Book in PDF, Epub and Kindle

In October 2011, the Institute of Medicine (IOM) released the report Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence, assessing the published evidence for the effectiveness of using cognitive rehabilitation therapy (CRT) to treat people with traumatic brain injury (TBI). TBI has gained increasing attention in the past 15 years because of its status as the signature wound of American military conflicts in Iraq and Afghanistan. Growing numbers of U.S. service members are suffering traumatic brain injuries and are surviving them, given that (a) the majority of traumatic brain injuries are mild and (b) lifesaving measures for more severe injuries have significantly improved. People with any level of injury can require ongoing health care in their recovery, helping them to regain (or compensate for) their losses of function and supporting their full integration into their social structure and an improved quality of life. One form of treatment for TBI is CRT, a systematic, goal-oriented approach to helping patients overcome cognitive impairments. The Department of Defense (DoD) asked the IOM to evaluate CRT for traumatic brain injury in order to guide the DoD's use and coverage in the Military Health System. Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Evaluating the Evidence was the IOM's resulting study of the evidence. The report's conclusions revolved around the fact that there is little continuity among research studies of the effectiveness of different types of CRT, and there exist only small amounts of evidence (or, in many cases, none) demonstrating the effectiveness of using CRT to treat TBI-although the evidence that does exist generally indicates that CRT interventions have some effectiveness. The workshop brought together experts in health services administration, research, and clinical practice from the civilian and military arenas in order to discuss the barriers for evaluating the effectiveness of CRT care and for identifying suggested taxonomy, terminology, timing, and ways forward for CRT researchers. The workshop consisted of individuals and was not intended to constitute a comprehensive group. Select decision makers in the Military Health System and Veterans Affairs (VA) and researchers were invited to participate. The workshop was designed to spur thinking about (1) the types of research necessary to move the field forward toward evidence-based clinical guidelines, (2) what the translational pipeline looks like and what its current deficiencies are, and (3) considerations that decision makers may choose to use as they decide what research they will support and decide how they will balance the urgency of the need with the level of evidence for CRT interventions. Cognitive Rehabilitation Therapy for Traumatic Brain Injury: Model Study Protocols and Frameworks to Advance the State of the Science summarizes the happenings of the workshop.

Brain Neurotrauma

Brain Neurotrauma
Author: Firas H. Kobeissy
Publisher: CRC Press
Total Pages: 718
Release: 2015-02-25
Genre: Medical
ISBN: 1466565993
GET BOOK

Download Brain Neurotrauma Book in PDF, Epub and Kindle

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.