Stimulated Raman Scattering Microscopy

Stimulated Raman Scattering Microscopy
Author: Ji-Xin Cheng
Publisher: Elsevier
Total Pages: 612
Release: 2021-12-04
Genre: Science
ISBN: 0323903371

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Stimulated Raman Scattering Microscopy: Techniques and Applications describes innovations in instrumentation, data science, chemical probe development, and various applications enabled by a state-of-the-art stimulated Raman scattering (SRS) microscope. Beginning by introducing the history of SRS, this book is composed of seven parts in depth including instrumentation strategies that have pushed the physical limits of SRS microscopy, vibrational probes (which increased the SRS imaging functionality), data science methods, and recent efforts in miniaturization. This rapidly growing field needs a comprehensive resource that brings together the current knowledge on the topic, and this book does just that. Researchers who need to know the requirements for all aspects of the instrumentation as well as the requirements of different imaging applications (such as different types of biological tissue) will benefit enormously from the examples of successful demonstrations of SRS imaging in the book. Led by Editor-in-Chief Ji-Xin Cheng, a pioneer in coherent Raman scattering microscopy, the editorial team has brought together various experts on each aspect of SRS imaging from around the world to provide an authoritative guide to this increasingly important imaging technique. This book is a comprehensive reference for researchers, faculty, postdoctoral researchers, and engineers. Includes every aspect from theoretic reviews of SRS spectroscopy to innovations in instrumentation and current applications of SRS microscopy Provides copious visual elements that illustrate key information, such as SRS images of various biological samples and instrument diagrams and schematics Edited by leading experts of SRS microscopy, with each chapter written by experts in their given topics

Coherent Raman Scattering Microscopy

Coherent Raman Scattering Microscopy
Author: Ji-Xin Cheng
Publisher: CRC Press
Total Pages: 603
Release: 2016-04-19
Genre: Science
ISBN: 1439867666

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The First Book on CRS MicroscopyCompared to conventional Raman microscopy, coherent Raman scattering (CRS) allows label-free imaging of living cells and tissues at video rate by enhancing the weak Raman signal through nonlinear excitation. Edited by pioneers in the field and with contributions from a distinguished team of experts, Coherent Raman Sc

Confocal Raman Microscopy

Confocal Raman Microscopy
Author: Jan Toporski
Publisher: Springer
Total Pages: 603
Release: 2018-03-01
Genre: Science
ISBN: 3319753800

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This second edition provides a cutting-edge overview of physical, technical and scientific aspects related to the widely used analytical method of confocal Raman microscopy. The book includes expanded background information and adds insights into how confocal Raman microscopy, especially 3D Raman imaging, can be integrated with other methods to produce a variety of correlative microscopy combinations. The benefits are then demonstrated and supported by numerous examples from the fields of materials science, 2D materials, the life sciences, pharmaceutical research and development, as well as the geosciences.

Visualizing Chemistry

Visualizing Chemistry
Author: National Research Council
Publisher: National Academies Press
Total Pages: 222
Release: 2006-06-01
Genre: Science
ISBN: 030916463X

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Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imagingâ€"the ability to visualize molecular structures and chemical composition in time and space as actual events unfoldâ€"from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Advances in Stimulated Raman Scattering Microscopy Via Deep Learning

Advances in Stimulated Raman Scattering Microscopy Via Deep Learning
Author: Bryce Adrian Manifold
Publisher:
Total Pages: 0
Release: 2022
Genre:
ISBN:

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Stimulated Raman scattering (SRS) microscopy is a powerful chemical imaging technique that acquires images based on the vibrational-spectral "fingerprints" of molecules within an imaged field of view often without the need for exogenous fluorophores or labels. SRS microscopy has found an established niche in biophotonics with many examples of translational clinical applications and demonstrations of imaging various biological systems on subcellular to tissue spatial orders. Concurrent to the development of SRS microscopy, computational advancements have seen a democratized adoption of deep learning platforms for a wide variety of computer vision tasks. In this work I document my contributions in integrating SRS microscopy and deep learning towards advancing the capability to study biological systems. Specifically, deep learning will be shown to address technical limitations of SRS microscopy such as imaging noise and ultimate imaging depth in tissue samples. Deep learning will also be shown to improve analysis of SRS images via the development of a novel convolutional neural network architecture designed to handle a variety of chemical imaging techniques and perform a variety of computer vision tasks. Finally, I will show how these advancements and novel architecture can be used to diagnose thyroid cancer in label-free human tissue samples and to classify and study T cells based on label-free images.

Near-Infrared Spectroscopy

Near-Infrared Spectroscopy
Author: Yukihiro Ozaki
Publisher: Springer Nature
Total Pages: 593
Release: 2020-11-13
Genre: Science
ISBN: 9811586489

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This book provides knowledge of the basic theory, spectral analysis methods, chemometrics, instrumentation, and applications of near-infrared (NIR) spectroscopy—not as a handbook but rather as a sourcebook of NIR spectroscopy. Thus, some emphasis is placed on the description of basic knowledge that is important in learning and using NIR spectroscopy. The book also deals with applications for a variety of research fields that are very useful for a wide range of readers from graduate students to scientists and engineers in both academia and industry. For readers who are novices in NIR spectroscopy, this book provides a good introduction, and for those who already are familiar with the field it affords an excellent means of strengthening their knowledge about NIR spectroscopy and keeping abreast of recent developments.

Bioimaging

Bioimaging
Author: Shoogo Ueno
Publisher: CRC Press
Total Pages: 273
Release: 2020-05-26
Genre: Medical
ISBN: 0429536569

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Bioimaging: Imaging by Light and Electromagnetics in Medicine and Biology explores new horizons in biomedical imaging and sensing technologies, from the molecular level to the human brain. It explores the most up-to-date information on new medical imaging techniques, such as the detection and imaging of cancer and brain diseases. This book also provides new tools for brain research and cognitive neurosciences based on new imaging techniques. Edited by Professor Shoogo Ueno, who has been leading the field of biomedical imaging for 40 years, it is an ideal reference book for graduate and undergraduate students and researchers in medicine and medical physics who are looking for an authoritative treatise on this expanding discipline of imaging and sensing in medicine and biology. Features: Provides step-by-step explanations of biochemical and physical principles in biomedical imaging Covers state-of-the art equipment and cutting-edge methodologies used in biomedical imaging Serves a broad spectrum of readers due to the interdisciplinary topic and approach Shoogo Ueno, Ph.D, is a professor emeritus of the University of Tokyo, Tokyo, Japan. His research interests include biomedical imaging and bioelectromagnetics, particularly in brain mapping and neuroimaging, transcranial magnetic stimulation (TMS), and magnetic resonance imaging (MRI). He was the President of the Bioelectromagnetics Society, BEMS (2003-2004) and the Chairman of the Commission K on Electromagnetics in Biology and Medicine of the International Union of Radio Science, URSI (2000-2003). He was named the IEEE Magnetics Society Distinguished Lecturer during 2010 and received the d’Arsonval Medal from the Bioelectromagnetics Society in 2010.

Modern Raman Spectroscopy

Modern Raman Spectroscopy
Author: Ewen Smith
Publisher: John Wiley & Sons
Total Pages: 248
Release: 2013-03-15
Genre: Science
ISBN: 1118681320

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This book reflects the dramatic increase in the number of Raman spectrometers being sold to and used by non-expert practitioners. It contains coverage of Resonance Raman and SERS, two hot areas of Raman, in a form suitable for the non-expert. Builds Raman theory up in stages without overloading the reader with complex theory Includes two chapters on instrumentation and interpretation that shows how Raman spectra can be obtained and interpreted Explains the potential of using Raman spectroscopy in a wide variety of applications Includes detailed, but concise information and worked examples