Monoclonal Antibodies in Headache

Monoclonal Antibodies in Headache
Author: Antoinette Maassen van den Brink
Publisher: Springer Nature
Total Pages: 172
Release: 2021-04-28
Genre: Medical
ISBN: 3030690326

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Intended to promote a more appropriate and modern therapeutic approach to migraine management, this book is the first to deal with monoclonal antibodies in this context. Authored by the most respected migraine experts from around the globe and drawing on the lessons learned in both clinical trials and clinical practice, it reviews the current state of knowledge on this important therapeutic innovation, which has produced impressive data in randomized controlled trials, and the efficacy and safety of which have been confirmed in day-to-day real-world use. Given its scope, the book will appeal to a broad range of specialists, including pharmacologists, clinical pharmacologists, neurologists and internists, but also to residents and medical students.

Calcitonin Gene-Related Peptide (CGRP) Mechanisms

Calcitonin Gene-Related Peptide (CGRP) Mechanisms
Author: Susan D. Brain
Publisher: Springer Nature
Total Pages: 198
Release: 2019-08-31
Genre: Medical
ISBN: 3030214540

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This book is designed to focus on the role of Calcitonin Gene-Related Peptide (CGRP) in health and disease. This peptide, originally discovered in the 1980s as a sensory neuropeptide with cardiovascular effects, is now known to play a distinct role in the pain processing of migraine. The various chapters address the origin, localization and function of CGRP and its receptor in the peripheral nervous system, in the cardiovascular system, and in other tissues and organs. Further attention is paid to the drug discovery pathway where recent findings show the beneficial effect of small molecule antagonists of the CGRP receptors for the relief of the migraine attack and of monoclonal antibodies against CGRP or the CGRP receptor for migraine prevention.

Managing Your Migraine

Managing Your Migraine
Author: Katy Munro
Publisher: Penguin UK
Total Pages: 224
Release: 2021-08-26
Genre: Health & Fitness
ISBN: 0241514290

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'A fantastic and much needed resource for all those suffering. Dr Katy Munro's experience and knowledge through this book will help all those who read it' Dr Rupy Aujla, The Doctor's Kitchen 'Dr Katy Munro is the single best migraine expert our family have ever met [...] This book brings hope to every migraineur' Miranda Sawyer, Guardian & Observer Journalist ***** Despite being one of the most common and debilitating conditions in the world, migraine is still widely misunderstood, stigmatised and misdiagnosed. Migraine is much more than 'just a headache', it's a genetic, neurological brain disorder, and it's time patients got the healp they really need. Managing Your Migraine is the practical go-to guide for understanding and treating migraine. In the book, headache Specialist and GP Dr Katy Munro will give you expert advice on: · Understanding your migraine phases and triggers · The impact of food, exercise and sleep on migraine · Rescue plans for acute attacks · Migraine preventers · Migraine in children · Managing your mental health with migraine If you're a person with migraine, or know someone struggling, this book will provide helpful strategies for alleviating your symptoms and managing your migraine. Drawing on her medical expertise, her own personal experience with migraine and the stories of her patients, Dr Munro will empower you to get to know your own migraine and build an effective treatment plan that will help you live your life more fully. Part of the Penguin Life Experts series.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
Total Pages: 848
Release: 1999
Genre: Medical
ISBN: 9780781719520

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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Migraine

Migraine
Author: Katherine Foxhall
Publisher: Johns Hopkins University Press
Total Pages: 293
Release: 2019-06-18
Genre: Medical
ISBN: 1421429489

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Deeply researched and beautifully written, this fascinating and accessible study of one of our most common, disabling—and yet often dismissed—disorders will appeal to physicians, historians, scholars in medical humanities, and people living with migraine alike.

Atlas of Headache Disorders and Resources in the World 2011

Atlas of Headache Disorders and Resources in the World 2011
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 0
Release: 2011
Genre: Medical
ISBN: 9789241564212

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"Despite that headache is felt at some time by nearly everybody, and almost half the world's adults at any one time have recent personal experience of one or more of the three very common headache disorders, much is unknown about the public-health impact of these conditions. It is not known how, or how much, they affect many of the populations of the world, or how healthcare and other resources are utilized to mitigate their effects. This first global enquiry into these matters illuminates the worldwide neglect of a major public-health problem, and reveals the inadequacies of responses to it in countries throughout the world. The Atlas of Headache Disorders presents data acquired by WHO in collaboration with Lifting The Burden: the Global Campaign against Headache. Most of the information was collected in a questionnaire survey of neurologists, general practitioners and patients' representatives from 101 countries, performed from October 2006 until March 2009. Epidemiological data were compiled from published studies through a systematic review, and supplemented by data gathered in population-based studies undertaken within the Global Campaign." --Publisher website.

The Pharmacology of Monoclonal Antibodies

The Pharmacology of Monoclonal Antibodies
Author: Martin Rosenberg
Publisher: Springer Science & Business Media
Total Pages: 414
Release: 2012-12-06
Genre: Medical
ISBN: 3642784321

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A sample of the most exciting developments in the cloning, manipulation, expression and application of genetically-engineered monoclonal antibodies. This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents. Leading scientists from academia and industry present their own findings as well as short reviews of these research areas.

Monoclonal Antibodies to Migraine

Monoclonal Antibodies to Migraine
Author: Emma M. Jones
Publisher:
Total Pages: 262
Release: 2014
Genre: History
ISBN: 9780902238954

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Drug-Induced Liver Injury

Drug-Induced Liver Injury
Author:
Publisher: Academic Press
Total Pages: 288
Release: 2019-07-13
Genre: Medical
ISBN: 0128173173

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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Update on Emerging Treatments for Migraine

Update on Emerging Treatments for Migraine
Author:
Publisher: Elsevier
Total Pages: 442
Release: 2020-09-05
Genre: Science
ISBN: 0128211091

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Update on Emerging Treatments for Migraine, Volume 255, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Updated release includes the latest information on Update on Emerging Treatments for Migraine