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| Author | : Ronald M. Burch |
| Publisher | : R. G. Landes |
| Total Pages | : 124 |
| Release | : 1993 |
| Genre | : Medical |
| ISBN | : |
| Author | : Stephen G. Farmer |
| Publisher | : Academic Press |
| Total Pages | : 371 |
| Release | : 1997-04-01 |
| Genre | : Medical |
| ISBN | : 0080542522 |
Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews:"A delicious masterpiece."--Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases. * * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins.* Provides a distinctly immunopharmacological approach to the kinin system.* Reviews of the role of kinins in disease and inlcudes data from human studies.* Includes information that is fully up-to-date and comprehensive.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 164 |
| Release | : 2012-12-26 |
| Genre | : Science |
| ISBN | : 1481603760 |
Kinins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Kinins. The editors have built Kinins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Kinins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Kinins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 17 |
| Release | : 2012-12-26 |
| Genre | : Medical |
| ISBN | : 1481642057 |
Bradykinin Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Bradykinin Receptors in a compact format. The editors have built Bradykinin Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bradykinin Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bradykinin Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
| Author | : |
| Publisher | : ScholarlyEditions |
| Total Pages | : 112 |
| Release | : 2013-06-21 |
| Genre | : Science |
| ISBN | : 148168924X |
Kinins—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Urotensins in a concise format. The editors have built Kinins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Urotensins in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Kinins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 408 |
| Release | : 2011-09-08 |
| Genre | : Science |
| ISBN | : 0123859530 |
G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones. In addition, emerging drug targets such as receptor families for fatty acids, carboxylic acids, lipid mediators, etc. are included. Final chapters cover novel mechanisms of signal regulation through PDZ domains and RGS proteins. This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones This volume will bring an up-to-date perspective on the G protein coupled receptor field to both academic and industry scientists
| Author | : Atsushi Miyamoto |
| Publisher | : |
| Total Pages | : 8 |
| Release | : 1997 |
| Genre | : |
| ISBN | : |
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 558 |
| Release | : 2011-07-13 |
| Genre | : Science |
| ISBN | : 0123855330 |
This is an overview of the fast-moving field of purinergic signalling through adenosine and ATP receptors. Authors are the leading authorities in their fields Subject matter is important for understanding tissue protection Subject matter is of intense interest for new drug development
| Author | : F. Sicuteri |
| Publisher | : Springer |
| Total Pages | : 688 |
| Release | : 1970 |
| Genre | : Science |
| ISBN | : |
Thus, new light is shed on basic problems involving the pathology of man as shock, angioneurotic edema, uratic arthritis, intracranial hemorrhage, and acute local and general reactions to thermal, mechanical and infectious assaults. It is with a certain degree of emotion that we now reconsider those terms and phenomena we were accustomed to seeing only from a cold biochemical point of view, such as the Hageman factor, the kallikrein inhibitor, and the permeability factor, under the warm light shed by the sufferings of man. This warmth, typical of human investigation, homogenized by the severity of experimental research, has contributed in making the scientific sessions more lively, and, above all, in creating the spontaneous and friendly atmosphere prevailing at Fiesole.
| Author | : Ronald M. Burch |
| Publisher | : Marcel Dekker |
| Total Pages | : 312 |
| Release | : 1991 |
| Genre | : Medical |
| ISBN | : |
Since 1985, when John Stewart and Ray Vavrek reported the first bradykinin analogs with antagonist activity at the B2 bradykinin receptor, several of the antagonists have been extensively used in studies of bradykinin receptor subtypes and of the role of bradykinin in blood pressure regulation, infl
