Modern Statistics for the Life Sciences
Author | : Alan Grafen |
Publisher | : |
Total Pages | : 351 |
Release | : 2002 |
Genre | : Mathematical statistics |
ISBN | : |
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Author | : Alan Grafen |
Publisher | : |
Total Pages | : 351 |
Release | : 2002 |
Genre | : Mathematical statistics |
ISBN | : |
Author | : SUSAN. HUBER HOLMES (WOLFGANG.) |
Publisher | : Cambridge University Press |
Total Pages | : 407 |
Release | : 2018 |
Genre | : |
ISBN | : 1108427022 |
Author | : Mark Chang |
Publisher | : Springer Science & Business Media |
Total Pages | : 316 |
Release | : 2011-07-15 |
Genre | : Medical |
ISBN | : 144199842X |
Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.
Author | : Rafael A. Irizarry |
Publisher | : CRC Press |
Total Pages | : 376 |
Release | : 2016-10-04 |
Genre | : Mathematics |
ISBN | : 1498775683 |
This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.
Author | : Pejaver Vishwamber Rao |
Publisher | : Duxbury Resource Center |
Total Pages | : 920 |
Release | : 1998 |
Genre | : Computers |
ISBN | : |
Appropriate for all courses in statistical methods for the agricultural, life, health, and environmental sciences, this book offers a practical and modern approach that minimizes computation and emphasizes conceptual understanding. Rao continually emphasizes issues and topics most relevant to modern day research in the life sciences. For example, point and interval estimation take priority over testing of statistical hypothesis and methods and guidelines for determination of sample size are indicated whenever possible. Statistical Research Methods in the Life Sciences also presents a self-contained and complete discussion of each experimental situation considered. In the two-sample setting, for example, in addition to presenting the procedures under the usual analysis of variance assumption, Rao also presents methods for checking the validity of the assumptions.
Author | : Justin C. Touchon |
Publisher | : Oxford University Press |
Total Pages | : 334 |
Release | : 2021-06-30 |
Genre | : Science |
ISBN | : 0192640127 |
The statistical analyses that students of the life-sciences are being expected to perform are becoming increasingly advanced. Whether at the undergraduate, graduate, or post-graduate level, this book provides the tools needed to properly analyze your data in an efficient, accessible, plainspoken, frank, and occasionally humorous manner, ensuring that readers come away with the knowledge of which analyses they should use and when they should use them. The book uses the statistical language R, which is the choice of ecologists worldwide and is rapidly becoming the 'go-to' stats program throughout the life-sciences. Furthermore, by using a single, real-world dataset throughout the book, readers are encouraged to become deeply familiar with an imperfect but realistic set of data. Indeed, early chapters are specifically designed to teach basic data manipulation skills and build good habits in preparation for learning more advanced analyses. This approach also demonstrates the importance of viewing data through different lenses, facilitating an easy and natural progression from linear and generalized linear models through to mixed effects versions of those same analyses. Readers will also learn advanced plotting and data-wrangling techniques, and gain an introduction to writing their own functions. Applied Statistics with R is suitable for senior undergraduate and graduate students, professional researchers, and practitioners throughout the life-sciences, whether in the fields of ecology, evolution, environmental studies, or computational biology.
Author | : Peter Bühlmann |
Publisher | : Springer Science & Business Media |
Total Pages | : 568 |
Release | : 2011-06-08 |
Genre | : Mathematics |
ISBN | : 364220192X |
Modern statistics deals with large and complex data sets, and consequently with models containing a large number of parameters. This book presents a detailed account of recently developed approaches, including the Lasso and versions of it for various models, boosting methods, undirected graphical modeling, and procedures controlling false positive selections. A special characteristic of the book is that it contains comprehensive mathematical theory on high-dimensional statistics combined with methodology, algorithms and illustrations with real data examples. This in-depth approach highlights the methods’ great potential and practical applicability in a variety of settings. As such, it is a valuable resource for researchers, graduate students and experts in statistics, applied mathematics and computer science.
Author | : Oliver Schabenberger |
Publisher | : CRC Press |
Total Pages | : 762 |
Release | : 2001-11-13 |
Genre | : Mathematics |
ISBN | : 1420040197 |
Despite its many origins in agronomic problems, statistics today is often unrecognizable in this context. Numerous recent methodological approaches and advances originated in other subject-matter areas and agronomists frequently find it difficult to see their immediate relation to questions that their disciplines raise. On the other hand, statisticians often fail to recognize the riches of challenging data analytical problems contemporary plant and soil science provides. The first book to integrate modern statistics with crop, plant and soil science, Contemporary Statistical Models for the Plant and Soil Sciences bridges this gap. The breadth and depth of topics covered is unusual. Each of the main chapters could be a textbook in its own right on a particular class of data structures or models. The cogent presentation in one text allows research workers to apply modern statistical methods that otherwise are scattered across several specialized texts. The combination of theory and application orientation conveys ìwhyî a particular method works and ìhowî it is put in to practice. About the downloadable resources The accompanying downloadable resources are a key component of the book. For each of the main chapters additional sections of text are available that cover mathematical derivations, special topics, and supplementary applications. It supplies the data sets and SAS code for all applications and examples in the text, macros that the author developed, and SAS tutorials ranging from basic data manipulation to advanced programming techniques and publication quality graphics. Contemporary statistical models can not be appreciated to their full potential without a good understanding of theory. They also can not be applied to their full potential without the aid of statistical software. Contemporary Statistical Models for the Plant and Soil Science provides the essential mix of theory and applications of statistical methods pertinent to research in life sciences.
Author | : Narayanaswamy Balakrishnan |
Publisher | : John Wiley & Sons |
Total Pages | : 1027 |
Release | : 2009-12-02 |
Genre | : Mathematics |
ISBN | : 0470405090 |
Inspired by the Encyclopedia of Statistical Sciences, Second Edition, this volume outlines the statistical tools for successfully working with modern life and health sciences research Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics, including: Sequential methods in biomedical research Statistical measures of human quality of life Change-point methods in genetics Sample size determination for clinical trials Mixed-effects regression models for predicting pre-clinical disease Probabilistic and statistical models for conception Statistical methods are explored and applied to population growth, disease detection and treatment, genetic and genomic research, drug development, clinical trials, screening and prevention, and the assessment of rehabilitation, recovery, and quality of life. These topics are explored in contributions written by more than 100 leading academics, researchers, and practitioners who utilize various statistical practices, such as election bias, survival analysis, missing data techniques, and cluster analysis for handling the wide array of modern issues in the life and health sciences. With its combination of traditional methodology and newly developed research, Methods and Applications of Statistics in the Life and Health Sciences has everything students, academics, and researchers in the life and health sciences need to build and apply their knowledge of statistical methods and applications.
Author | : Thorsten Dickhaus |
Publisher | : Springer Science & Business Media |
Total Pages | : 182 |
Release | : 2014-01-23 |
Genre | : Science |
ISBN | : 3642451829 |
This monograph will provide an in-depth mathematical treatment of modern multiple test procedures controlling the false discovery rate (FDR) and related error measures, particularly addressing applications to fields such as genetics, proteomics, neuroscience and general biology. The book will also include a detailed description how to implement these methods in practice. Moreover new developments focusing on non-standard assumptions are also included, especially multiple tests for discrete data. The book primarily addresses researchers and practitioners but will also be beneficial for graduate students.