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| Release | : 2006 |
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| Author | : O. Diekmann |
| Publisher | : John Wiley & Sons |
| Total Pages | : 324 |
| Release | : 2000-04-07 |
| Genre | : Mathematics |
| ISBN | : 9780471492412 |
Mathematical Epidemiology of Infectious Diseases Model Building, Analysis and Interpretation O. Diekmann University of Utrecht, The Netherlands J. A. P. Heesterbeek Centre for Biometry Wageningen, The Netherlands The mathematical modelling of epidemics in populations is a vast and important area of study. It is about translating biological assumptions into mathematics, about mathematical analysis aided by interpretation and about obtaining insight into epidemic phenomena when translating mathematical results back into population biology. Model assumptions are formulated in terms of, usually stochastic, behaviour of individuals and then the resulting phenomena, at the population level, are unravelled. Conceptual clarity is attained, assumptions are stated clearly, hidden working hypotheses are attained and mechanistic links between different observables are exposed. Features: * Model construction, analysis and interpretation receive detailed attention * Uniquely covers both deterministic and stochastic viewpoints * Examples of applications given throughout * Extensive coverage of the latest research into the mathematical modelling of epidemics of infectious diseases * Provides a solid foundation of modelling skills The reader will learn to translate, model, analyse and interpret, with the help of the numerous exercises. In literally working through this text, the reader acquires modelling skills that are also valuable outside of epidemiology, certainly within population dynamics, but even beyond that. In addition, the reader receives training in mathematical argumentation. The text is aimed at applied mathematicians with an interest in population biology and epidemiology, at theoretical biologists and epidemiologists. Previous exposure to epidemic concepts is not required, as all background information is given. The book is primarily aimed at self-study and ideally suited for small discussion groups, or for use as a course text.
| Author | : WHO Regional Office for the Western Pacific |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2011 |
| Genre | : Coxsackievirus infections |
| ISBN | : 9789290615255 |
Hand, foot and mouth disease (HFMD) is a common infectious disease caused by a group of enteroviruses, including coxsackievirus A16 (CA16) and enterovirus 71 (EV71). Over the last decade, many outbreaks of HFMD have been reported in countries of the Western Pacific Region. HFMD caused by EV71 is of particular concern because of the increased number of deaths associated with infection. Until now, there has been little guidance on HFMD caused by EV71. This publication provides practical support for the treatment, prevention and control of HFMD based on the most recent scientific literature and the current understanding and experiences of international experts. It is intended as a resource for both clinicians working with HFMD cases on a regular basis and for public health personnel who are responsible for preventing and responding to outbreaks of HFMD.
| Author | : Alfred S. Evans |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 744 |
| Release | : 2013-11-11 |
| Genre | : Medical |
| ISBN | : 1468447270 |
also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.
| Author | : Dongmei Chen |
| Publisher | : John Wiley & Sons |
| Total Pages | : 496 |
| Release | : 2014-12-08 |
| Genre | : Medical |
| ISBN | : 1118629914 |
Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.
| Author | : Piero Manfredi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 329 |
| Release | : 2013-01-04 |
| Genre | : Mathematics |
| ISBN | : 1461454743 |
This volume summarizes the state-of-the-art in the fast growing research area of modeling the influence of information-driven human behavior on the spread and control of infectious diseases. In particular, it features the two main and inter-related “core” topics: behavioral changes in response to global threats, for example, pandemic influenza, and the pseudo-rational opposition to vaccines. In order to make realistic predictions, modelers need to go beyond classical mathematical epidemiology to take these dynamic effects into account. With contributions from experts in this field, the book fills a void in the literature. It goes beyond classical texts, yet preserves the rationale of many of them by sticking to the underlying biology without compromising on scientific rigor. Epidemiologists, theoretical biologists, biophysicists, applied mathematicians, and PhD students will benefit from this book. However, it is also written for Public Health professionals interested in understanding models, and to advanced undergraduate students, since it only requires a working knowledge of mathematical epidemiology.
| Author | : H.S.H Seifert |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 586 |
| Release | : 1996-06-30 |
| Genre | : Medical |
| ISBN | : 9780792338215 |
This book, Tropical Animal Health, describes the problems of animal diseases in the tropics, in the tropical environment, and in relation to particular production systems. In Part I, those basic scientific facts of the special host defence mechanism and of the host-pathogen relationship in the tropics, which hardly play any part in animal husbandry in temperate climates, are explained. Of special importance are the resistance mechanisms of autochthonous breeds and in contrast to them, the high susceptibility of exotic breeds in the tropics. It is explained how immuno- and chemoprophylaxis can be used as instruments for animal health measures if they are adapted to the socio-economic and ecological conditions of both the tropics and developing countries. Scientific details of immunology are presented as far as they are necessary to understand the epizo otiology of tropical diseases and diagnostic techniques for recognizing tropical diseases as well as the execution of prophylactic measures. Vector-borne diseases are the disease complexes most difficult to control since they are bound to the tropical environment, thanks to the biology of their vectors. Therefore, a special chapter has been dedicated to the description of biology and eradication of vectors of vector-borne diseases. The extent of the description varies according to the importance of the specific vector. The acaricides, insecticides and alternative methods used to control vectors are dis cussed in detail. The author has tried to present a world-wide picture, but it is not possible to cover every aspect completely.
| Author | : Paul Elliott |
| Publisher | : |
| Total Pages | : 506 |
| Release | : 2000 |
| Genre | : Epidemiology |
| ISBN | : |
This is a new paperback edition of the well received text Spatial Epid emiology: Methods and Applications. It is an easy to read, clear and c oncise exploration of the field of geographical variations in diseases . Especially with respect to variations in environmental exposures at the small-area scale this book gives an authoriative account of curren t practice and developments. The recent and rapid expansion of the fie ld looks set to continue in line with growing public, governmental and media concern about environmental and health issues, and the scientif ic need to understand and explain the effects of environmental polluta nts on health.
| Author | : Ottar N. Bjørnstad |
| Publisher | : Springer |
| Total Pages | : 312 |
| Release | : 2018-10-30 |
| Genre | : Medical |
| ISBN | : 3319974874 |
This book is designed to be a practical study in infectious disease dynamics. The book offers an easy to follow implementation and analysis of mathematical epidemiology. The book focuses on recent case studies in order to explore various conceptual, mathematical, and statistical issues. The dynamics of infectious diseases shows a wide diversity of pattern. Some have locally persistent chains-of-transmission, others persist spatially in ‘consumer-resource metapopulations’. Some infections are prevalent among the young, some among the old and some are age-invariant. Temporally, some diseases have little variation in prevalence, some have predictable seasonal shifts and others exhibit violent epidemics that may be regular or irregular in their timing. Models and ‘models-with-data’ have proved invaluable for understanding and predicting this diversity, and thence help improve intervention and control. Using mathematical models to understand infectious disease dynamics has a very rich history in epidemiology. The field has seen broad expansions of theories as well as a surge in real-life application of mathematics to dynamics and control of infectious disease. The chapters of Epidemics: Models and Data using R have been organized in a reasonably logical way: Chapters 1-10 is a mix and match of models, data and statistics pertaining to local disease dynamics; Chapters 11-13 pertains to spatial and spatiotemporal dynamics; Chapter 14 highlights similarities between the dynamics of infectious disease and parasitoid-host dynamics; Finally, Chapters 15 and 16 overview additional statistical methodology useful in studies of infectious disease dynamics. This book can be used as a guide for working with data, models and ‘models-and-data’ to understand epidemics and infectious disease dynamics in space and time.
| Author | : William P. Taylor |
| Publisher | : Elsevier |
| Total Pages | : 390 |
| Release | : 2005-11-15 |
| Genre | : Nature |
| ISBN | : 0080455891 |
Rinderpest and Peste des Petits Ruminants tells the story of how, by the year 2010, scientists are set to globally eradicate one of the great historic plagues that has ravaged human livestock for centuries. Descriptions of the disease in Europe date back to the 4th century and it was regularly re-introduced following wars and other civil unrest until late in the 19th century. It was introduced with devastating effect into Africa towards the end of the 19th century and is now widespread across sub-Saharan Africa, the Middle East and Southern Asia. Its causative agent, rinderpest virus, a morbillivirus very closely related to human measles virus, decimates the cattle population along with those of other susceptible domestic ruminants and many wildlife species wherever it is present. The history of Rinderpest including the history of vaccines and vaccination Details other Morbillaviruses Epidemiology and transmission of Rinderpest
