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| Author | : Geek Realm |
| Publisher | : |
| Total Pages | : 122 |
| Release | : 2019-07-23 |
| Genre | : |
| ISBN | : 9781082196751 |
Grab this amazing Funny Biology Notebook for yourself or someone who's interested in science. The paperback notebook consists of 120 pages, size 6x9 inches.- 6x9 Notebook- 120 Pages Count- Paperback Cover
| Author | : Nick Lane |
| Publisher | : OUP Oxford |
| Total Pages | : 553 |
| Release | : 2006-10-26 |
| Genre | : Science |
| ISBN | : 0191622591 |
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
| Author | : Sabzali Javadov |
| Publisher | : Frontiers E-books |
| Total Pages | : 122 |
| Release | : 2014-09-23 |
| Genre | : Biology (General) |
| ISBN | : 2889192830 |
Mitochondrion, a sub-cellular organelle originated from primary endosymbiosis, plays a vital role in energy metabolism of eukaryotic cells. The transfer of electrons through the electron transport chain (ETC) to molecular oxygen accompanied by the extrusion of protons from the matrix generate an electrochemical gradient across the inner mitochondrial membrane (IMM) that is used for ATP synthesis by oxidative phosphorylation. Despite many aspects of ATP synthesis have been delineated, regulatory mechanisms responsible for energy synthesis and transfer still remain to be uncovered. In addition to energy function, mitochondria play a crucial role in cell metabolism under both physiological and pathological conditions through their participation in many intracellular signaling pathways. Studies over the last 30 years provide strong evidence that mitochondria are the nexus of various stresses which initiate cell death through apoptosis, oncosis, necrosis and autophagy depending on the severity of the stress and cellular energy status. The release of several pro-apoptotic proteins such as cytochrome c, Smac/DIABLO, AIF, endonuclease G from intermembrane space initiates both caspase-dependent and caspase-independent apoptosis. The formation of the mitochondrial permeability transition pore in the IMM promotes cell death mostly through necrosis whereas a mild stress activates autophagy. Due to their critical roles in both cell death and survival mitochondria have been widely considered as an important target for various pharmacological and conditional therapeutic approaches. Currently, a large number of mitochondria-targeted agents are suggested to prevent (in ischemia reperfusion injury, cardiovascular, neurodegenerative and other diseases) or stimulate (in various cancers) cell death. This Research Topic focuses on the role of mitochondria in the regulation of cell metabolism and signaling under physiological and pathological conditions. Studies performed on cultured cells and isolated organs/tissues using different animal and cellular models of various diseases are also included and discussed.
| Author | : Ruang Saintek |
| Publisher | : Tiram Media |
| Total Pages | : 53 |
| Release | : 2024-04-19 |
| Genre | : Science |
| ISBN | : |
"Exploring Mitochondria: Unraveling the Powerhouses of the Cell" is a comprehensive journey into the intricate world of mitochondria, the dynamic organelles responsible for powering cellular activities. This book offers an in-depth exploration of the structure, function, and significance of mitochondria in various biological processes. Beginning with an introduction to mitochondria, the book dives into their complex structure and multifaceted functions within cells. It discusses the evolutionary origins of mitochondria and their symbiotic relationship with eukaryotic cells, shedding light on the pivotal role they play in cellular metabolism and energy production. Moreover, the book explores the emerging understanding of mitochondria's involvement in cellular signaling pathways, aging, and various diseases, including cancer, neurodegenerative disorders, and metabolic diseases. Readers will gain insights into the intricate interplay between mitochondria and the nucleus, highlighting the coordination required for cellular homeostasis and adaptation to changing environmental conditions. With discussions on cutting-edge technologies driving mitochondrial research forward, this book serves as a valuable resource for students, researchers, and anyone intrigued by the profound impact of mitochondria on cellular function and human health. Through accessible language and illustrative examples, "Exploring Mitochondria" offers a captivating journey into the powerhouses of the cell.
| Author | : Barbara ABREGO |
| Publisher | : |
| Total Pages | : 114 |
| Release | : 2020-12-11 |
| Genre | : |
| ISBN | : |
Mitochondria Power Co Powerhouse Of The Cells Cience/h3>
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 519 |
| Release | : 2001-05-23 |
| Genre | : Science |
| ISBN | : 008052253X |
This title employs biochemical, cell biological, and genetic approaches to study mitochondrial structure, function, and biogenesis. Also of interest are the consequences of impaired mitochondrial function on cells, tissues, and organs. The book is full of step-by-step "how to" methods with sample results, interpretations, and pitfalls. There is a unique set of appendices that include gene catalogs, mtDNA maps, and reagents for probing respiratory chain function. Finally, there are applications of state-of-the art microarray and gene chip technologies. Isolation of mitochondria from commonly used cells and tissues Assays for mitochondrial activities, including respiration, ATP production, permeability, protein import, and interactions with the cytoskeleton Biochemical and optical methods for studying protein-protein interactions in mitochondria Approaches to studying mitochondrial replication, transcription, and translation Transmitochondrial technologies Methods in microassay data analysis
| Author | : Immo E. Scheffler |
| Publisher | : Wiley-Liss |
| Total Pages | : 0 |
| Release | : 1999-07-05 |
| Genre | : Science |
| ISBN | : 9780471194224 |
Mitochondria are complex organelles, possessing inner and outer membranes and even their own DNA. A typical cell contains 800 mitochondria, termed the "powerhouse of the cell", playing a central role in metabolism, respiration, and ATF production. Mitochondria is the first modern, truly comprehensive authored book which tackles the biochemistry, genetics, and pathology of mitochondria in different organisms.
| Author | : Quan Chen |
| Publisher | : CRC Press |
| Total Pages | : 300 |
| Release | : 2016-01-15 |
| Genre | : Medical |
| ISBN | : 9781482230031 |
Mitochondria are among the most important of eukaryotic cell organelles, often referred to as the "powerhouse" of the cell, because of the role they play in providing energy for cellular function. This book synthesizes what is known mitochondrial dynamics, including the fusion and fission of mitochondria, mitophagy (the destruction of damaged mitochondria), and the role of mitochondrial dynamics in disease such as Parkinson's disease and diabetes--among other topics. The volume is designed to appeal to molecular biologists, cell physiologists and anyone interested in the role mitochondria play in cell physiological function.
| Author | : Greg LeMond |
| Publisher | : Academic Cell |
| Total Pages | : 0 |
| Release | : 2016-03-15 |
| Genre | : |
| ISBN | : 9780128010303 |
Mitochondrial Fitness: The Science of Athletic Energy will take you inside the human cell, providing a deeper knowledge, revealing the biological basis of athletic genetic gift, the science of sports nutrition and dietary requirements, the various fuels cells consumed and stored protein synthetic function, and the processes of recovery and rebuilding. Focusing on cellular and subcellular levels of athletic energy, this reference text will cover everything from sports nutrition and hydration at the cellular level to a core understanding of mitochondria. In addition to helping physiologists, biologists, and physicians understand the true science behind fitness, this book will assist elite athletes in achieving natural, optimal performance as well as recreational athletes to improve overall fitness, health, and vitality. Reveals the biological basis of althletic genetic gift, the science of sport nutrition and dietary requirements, the fuel cells consume and store, protein synthetic function, and the processes of recovery and building. Explains the relationship between diseases and toxins that impair mitochondria, one of the contributors to the epidemics of metabolic syndrome, obesity, type 2 diabetes, many degenerative diseases, as well as the latest theory of aging. Helps physiologists, biologists, and physicians understand the true science behind fitness and assists athletes in achieving natural, optimal performance as well as recreational athletes to improve overall fitness, health, and vitality.
| Author | : Alexander Tzagoloff |
| Publisher | : Springer |
| Total Pages | : 342 |
| Release | : 1982-04-01 |
| Genre | : Science |
| ISBN | : 9780306407789 |
In writing this book, I found the choice of a suitable title to be a most vexing problem. Lehninger's excellent earlier monograph The Mitochondrion had already appropriated in the domain of library cards what appeared to be the most fitting description of the subject matter. Once the text was completed, however, it became obvious that pluralization was the simplest solution to this dilemma. Variations in the structure and function of this organelle and recent discoveries of the phylogenetic diversity in the organization and genetic con tent of its DNA all seemed to justify the idea that there are as many different mitochondria as there are mitochondriologists. Even though my initial intention was to provide advanced undergraduate and graduate students of cell biology with supplemental reading material on topics usually dealt with in a cursory manner by most standard texts, inevitably the scope was broadened to attract the interest of more seasoned readers who might be familiar with some but not other areas of mitochondrial studies. Con sistent with the original aim, literature citations have been kept to a minimum and are avoided in the main body of the text for purposes of readability.
