Metallotherapeutic Drugs and Metal-Based Diagnostic Agents

Metallotherapeutic Drugs and Metal-Based Diagnostic Agents
Author: Marcel Gielen
Publisher: John Wiley & Sons
Total Pages: 638
Release: 2005-09-01
Genre: Science
ISBN: 0470864044

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There are an astonishing number and variety of roles that metals play in contemporary medicine. This book contains information on the medicinal uses of inorganics, that is, of elements such as boron, lithium, selenium, to name a few, as well as metal-containing species. In keeping with the notion that healthy mammals rely on (bio-essential) metals for the normal functioning of approximately a third of their proteins and enzymes, a large number of drugs are metal-based and considerable effort is being devoted to developing both second- and third-generation drugs as well as generating novel metal-based drugs. While there is no doubt that there is an emphasis on 'Metallotherapeutics' throughout the volume, the use of metals in medicine is not restricted to metal-based drugs. The following are also covered: non-invasive radiopharmaceuticals Magnetic Resonance Imaging (MRI) mineral supplements From the foregoing and, more importantly, from the contents of the various Chapters, the reader will gain an appreciation of the very real role metal-based drugs play in modern medicine and of the considerable effort being devoted to the development of novel complexes with greater efficacy as therapeutic and diagnostic agents.

Metals in Medicine

Metals in Medicine
Author: James C. Dabrowiak
Publisher: John Wiley & Sons
Total Pages: 751
Release: 2017-05-02
Genre: Science
ISBN: 1119191343

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Working from basic chemical principles, Metals in Medicine, 2nd Edition describes a wide range of metal-based agents for treating and diagnosing disease. Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the first edition. Topics include: Metallo-Drugs and their action Platinum drugs for treating cancer Anticancer agents beyond cisplatin including ruthenium, gold, titanium and gallium Responsive Metal Complexes Treating arthritis and diabetes with metal complexes Metal complexes for killing bacteria, parasites and viruses Metal ion imbalance and its links to diseases including Alzheimer's, Wilson's and Menkes disease Metal complexes for detecting disease Nanotechnology in medicine Now in full colour, Metals in Medicine, 2nd Edition employs real-life applications and chapter-end summaries alongside feature boxes and problems. It provides a complete and methodical examination of the use of metal complexes in medicine for advanced undergraduate and postgraduate students in medicinal inorganic chemistry, bioinorganic chemistry, biochemistry, pharmacology, biophysics, biology and bioengineering. It is also an invaluable resource for academic researchers and industrial scientists in inorganic chemistry, medicinal chemistry and drug development.

Essentials of Inorganic Chemistry

Essentials of Inorganic Chemistry
Author: Katja A. Strohfeldt
Publisher: John Wiley & Sons
Total Pages: 290
Release: 2015-02-16
Genre: Science
ISBN: 0470665580

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A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health-care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand-alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.

Chemistry of Precious Metals

Chemistry of Precious Metals
Author: S.A. Cotton
Publisher: Springer Science & Business Media
Total Pages: 386
Release: 2012-12-06
Genre: Science
ISBN: 9400914636

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Some 20 years ago, I was privileged to share in writing a book on the descriptive chemistry of the 4d, 5d, 4f and 5f metals that included these eight elements within its compass (S.A. Cotton and F.A. Hart, The Heavy Transition Elements, Macmillan, 1975). This volume shares the same aim of covering the descriptive chemistry of silver, gold and the six platinum metals in some detail at a level suitable for advanced undergraduate and postgraduate study. It does not attempt to be a comprehensive treatise on the chemistry of these metals. It attempts to fill a slot between the general text and the in-depth review or monograph. The organometallic chemistry is confined to a-bonded com pounds in normal oxidation states; compounds with IT-bonding ligands are generally excluded. Their inclusion would have increased the length of the book considerably and, moreover, their recent chemistry has been extensively and expertly reviewed in the new Comprehensive Organometallic Chemistry, II, eds G. Wilkinson, F.G.A. Stone and E.W. Abel, Pergamon, Oxford, 1995.

Organometallic Chemistry

Organometallic Chemistry
Author: Marcel Gielen
Publisher: Wiley
Total Pages: 288
Release: 2008-06-24
Genre: Science
ISBN: 9780470779514

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Organometallic Chemistry comprises of seven essential references. Click on the individual titles for further information about the volumes included in the set. Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine Marcel Gielen (Editor), Edward R.T. Tiekink (Editor) ISBN: 978-0-470-86403-6 Hardcover | 638 pages Publication Date: March 2005 Handbook of Metalloproteins, 3-Volume Set Albrecht Messerschmidt (Editor) ISBN: 978-0-470-86981-9 Hardcover | 2308 pages Publication Date: March 2004 Fluxional Organometallic and Coordination Compounds Marcel Gielen (Editor), Rudolph Willem (Editor), Bernd Wrackmeyer (Editor) ISBN: 978-0-470-85839-4 Hardcover | 340 pages Publication Date: August 2004 Unusual Structures and Physical Properties in Organometallic Chemistry Marcel Gielen (Editor), Rudolph Willem (Editor), Bernd Wrackmeyer (Editor) ISBN: 978-0-471-49635-9 Hardcover | 446 pages Publication Date: September 2002 Solid State Organometallic Chemistry: Methods and Applications Marcel Gielen (Editor), Rudolph Willem (Editor), Bernd Wrackmeyer (Editor) ISBN: 978-0-471-97920-3 Hardcover | 548 pages Publication Date: October 1999

Medicinal Inorganic Chemistry

Medicinal Inorganic Chemistry
Author: Jonathan L. Sessler
Publisher:
Total Pages: 480
Release: 2005
Genre: Medical
ISBN:

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This book reviews the current diagnostic and therapeutic uses of metal-containing compounds in medicine, as well as the role of metals in disease.

Metal Nanoparticles

Metal Nanoparticles
Author: Sreekanth Thota
Publisher: John Wiley & Sons
Total Pages: 375
Release: 2017-12-20
Genre: Science
ISBN: 352780708X

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A much-needed summary of the importance, synthesis and applications of metal nanoparticles in pharmaceutical sciences, with a focus on gold, silver, copper and platinum nanoparticles. After a brief introduction to the history of metal complexes in medicine and fundamentals of nanotechnology, the chapters continue to describe different methods for preparation of metal nanoparticles. This section is followed by representative presentations of current biomedical applications, such as drug delivery, chemotherapy, and diagnostic imaging. Aimed at stimulating further research in this field, the book serves as an reference guide for academics and professionals working in the field of chemistry and nanotechnology.

Fluxional Organometallic and Coordination Compounds

Fluxional Organometallic and Coordination Compounds
Author: Marcel Gielen
Publisher: John Wiley & Sons
Total Pages: 340
Release: 2005-01-28
Genre: Science
ISBN: 0470858443

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This series offers leading contributions by well-known chemists reviewing the state of the art of this wide research area. Physical organometallic chemistry aims to develop new insights and to promote novel interest and investigations applicable to organometallic chemistry. This volume focuses on several important topics on fluxionality in organometallic and coordination chemistry, reviewed by experts in each of the respective fields. It is intended to provide both authoritative concepts and stimulating ideas in order to tackle dynamics from different angles, aiming at an interdisciplinary approach. The fascinating fluxionality of metal-ligand interactions has been in the centre of interest ever since modern coordination and organometallic chemistry started, and has expanded towards bioinorganic chemistry, catalysis and materials sciences. Provides information on some of the most relevant physical methods for studying dynamic processes Presents numerous examples of dynamic behavior, demonstrating the efficiency of the respective method and stimulating further applications Connects main group, transition metal and solid state chemistry in the question for dynamics

Miracle Cure

Miracle Cure
Author: Kazuhiko Asai
Publisher: Kodansha
Total Pages: 171
Release: 1980-01-01
Genre: Medical
ISBN: 9780870404740

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