Mathematical Population Genetics 1

Mathematical Population Genetics 1
Author: Warren J. Ewens
Publisher: Springer Science & Business Media
Total Pages: 448
Release: 2004-01-09
Genre: Science
ISBN: 9780387201917

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This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Mathematical Population Genetics 1

Mathematical Population Genetics 1
Author: Warren J. Ewens
Publisher: Springer Science & Business Media
Total Pages: 435
Release: 2012-10-01
Genre: Science
ISBN: 038721822X

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This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.

Foundations of Mathematical Genetics

Foundations of Mathematical Genetics
Author: Anthony William Fairbank Edwards
Publisher: Cambridge University Press
Total Pages: 138
Release: 2000-01-13
Genre: Science
ISBN: 9780521775441

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A definitive account of the origins of modern mathematical population genetics, first published in 2000.

Some Mathematical Models from Population Genetics

Some Mathematical Models from Population Genetics
Author: Alison Etheridge
Publisher: Springer
Total Pages: 129
Release: 2011-01-05
Genre: Mathematics
ISBN: 3642166326

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This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.

Mathematical Population Genetics

Mathematical Population Genetics
Author: W. J. Ewens
Publisher: Springer
Total Pages: 354
Release: 1979-11
Genre: Mathematics
ISBN:

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Human Population Genetics

Human Population Genetics
Author: John H. Relethford
Publisher: John Wiley & Sons
Total Pages: 326
Release: 2012-03-27
Genre: Science
ISBN: 0470464674

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Introductory guide to human population genetics and microevolutionary theory Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain theories central to the field. By describing changes in the frequency of genetic variants from one generation to the next, this book hones in on the mathematical basis of evolutionary theory. Human Population Genetics includes: Helpful formulae for learning ease Graphs and analogies that make basic points and relate the evolutionary process to mathematical ideas Glossary terms marked in boldface within the book the first time they appear In-text citations that act as reference points for further research Exemplary case studies Topics such as Hardy-Weinberg equilibrium, inbreeding, mutation, genetic drift, natural selection, and gene flow Human Population Genetics solidifies knowledge learned in introductory biological anthropology or biology courses and makes it applicable to genetic study. NOTE: errata for the first edition can be found at the author's website: http://employees.oneonta.edu/relethjh/HPG/errata.pdf

Information Geometry and Population Genetics

Information Geometry and Population Genetics
Author: Julian Hofrichter
Publisher: Springer
Total Pages: 323
Release: 2017-02-23
Genre: Mathematics
ISBN: 3319520458

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The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.

Mathematical Structures in Population Genetics

Mathematical Structures in Population Genetics
Author: Yuri I. Lyubich
Publisher: Springer
Total Pages: 0
Release: 2011-12-14
Genre: Mathematics
ISBN: 9783642762130

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Mathematical methods have been applied successfully to population genet ics for a long time. Even the quite elementary ideas used initially proved amazingly effective. For example, the famous Hardy-Weinberg Law (1908) is basic to many calculations in population genetics. The mathematics in the classical works of Fisher, Haldane and Wright was also not very complicated but was of great help for the theoretical understanding of evolutionary pro cesses. More recently, the methods of mathematical genetics have become more sophisticated. In use are probability theory, stochastic processes, non linear differential and difference equations and nonassociative algebras. First contacts with topology have been established. Now in addition to the tra ditional movement of mathematics for genetics, inspiration is flowing in the opposite direction, yielding mathematics from genetics. The present mono grapll reflects to some degree both patterns but especially the latter one. A pioneer of this synthesis was S. N. Bernstein. He raised-and partially solved- -the problem of characterizing all stationary evolutionary operators, and this work was continued by the author in a series of papers (1971-1979). This problem has not been completely solved, but it appears that only cer tain operators devoid of any biological significance remain to be addressed. The results of these studies appear in chapters 4 and 5. The necessary alge braic preliminaries are described in chapter 3 after some elementary models in chapter 2.

Theoretical Population Genetics

Theoretical Population Genetics
Author: J.S. Gale
Publisher: Springer Science & Business Media
Total Pages: 428
Release: 2012-12-06
Genre: Science
ISBN: 9400903871

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The rise of the neutral theory of molecular evolution seems to have aroused a renewed interest in mathematical population genetics among biologists, who are primarily experimenters rather than theoreticians. This has encouraged me to set out the mathematics of the evolutionary process in a manner that, I hope, will be comprehensible to those with only a basic knowledge of calculus and matrix algebra. I must acknowledge from the start my great debt to my students. Equipped initially with rather limited mathematics, they have pursued the subject with much enthusiasm and success. This has enabled me to try a number of different approaches over the years. I was particularly grateful to Dr L. J. Eaves and Professor W. E. Nance for the opportunity to give a one-semester course at the Medical College of Virginia, and I would like to thank them, their colleagues and their students for the many kindnesses shown to me during my visit. I have concentrated almost entirely on stochastic topics, since these cause the greatest problems for non-mathematicians. The latter are particularly concerned with the range of validity of formulae. A sense of confidence in applying these formulae is, almost certainly, best gained by following their derivation. I have set out proofs in fair detail, since, in my experience, minor points of algebraic manipulation occasionally cause problems. To avoid loss of continuity, I have sometimes put material in notes at the end of chapters.

From Genetics to Mathematics

From Genetics to Mathematics
Author: Miroslaw Lachowicz
Publisher: World Scientific
Total Pages: 242
Release: 2009
Genre: Science
ISBN: 9812837256

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This volume contains pedagogical and elementary introductions to genetics for mathematicians and physicists as well as to mathematical models and techniques of population dynamics. It also offers a physicist''s perspective on modeling biological processes. Each chapter starts with an overview followed by the recent results obtained by authors. Lectures are self-contained and are devoted to various phenomena such as the evolution of the genetic code and genomes, age-structured populations, demography, sympatric speciation, the Penna model, Lotka-Volterra and other predator-prey models, evolutionary models of ecosystems, extinctions of species, and the origin and development of language. Authors analyze their models from the computational and mathematical points of view.