This volume presents a systematic approach to the methods of procurement and examination of bone marrow (aspiration and trephine biopsy) samples that play a crucial role in the diagnosis and management of patients with various hematological, as well as non-hematological, conditions. It systematically explains how to obtain and process bone marrow samples and outlines the methods employed to carry out this specialized clinical procedure safely and effectively. Both aspiration and trephine (core) biopsy techniques are described in detail with the relative merits and illustrations of each highlighted. The book discusses both common problems and rare complications, and offers practical advice on how they may be resolved. In addition, it offers a step-by-step guide with illustrations demonstrating how to obtain aspirations and trephine (core) biopsy specimens at the bedside or in a minor operating room. Included in this informative book are a state-of-the-art review of aspiration and trephine (core) biopsy, a practical illustrated guide to technique and procedures, a description of recent developments and indications for the future. This book will be of benefit to all who are involved in procuring and interpreting bone marrow specimens, including trainee and practicing hematologists, hematopathologists, oncologists, interventional radiologists, junior doctors and nurse practitioners. It will also serve as a reference for technicians and nurses.