Primarily intended for DNP and PhD students in nursing and health care who are expected to design research to identify health-related problems and solutions, this book focuses on the concepts, theories and processes of how social determinants affect the health of populations. Using specific social determinants as an organizing framework, it presents ample scientific evidence from health and social disciplines of the universal processes that produce the social patterning of health inequities. This book is organized into three major parts, beginning with the social pathways to health vulnerability, followed by research methods and subsequently frameworks for action. The methods section provides selected research approaches suitable for studying the impact of social variables on population health, as well as the outcomes of multilevel interventions. Each chapter provides an in-depth presentation of relevant theoretical knowledge and research-based examples of work conducted in the area. The book addresses the specific implications for health professional leaders such as nurses or health policy makers, highlighting their role in achieving macrosocial changes to promote health among specific vulnerable populations. Both of the book’s editors are prominent and highly respected scholars in their field. The team of authors is highly multidisciplinary, including experts from the fields of medicine, public health, education and epidemiology who have conducted research on the social determinants of population health. Combining their varied perspectives, this book offers a valuable resource for graduate students (PhD, MD, DNP, MSN, etc.), faculty, researchers and clinicians in health professions.