Lipoproteins in Health and Disease

Lipoproteins in Health and Disease
Author: John Betteridge
Publisher: CRC Press
Total Pages: 1328
Release: 1999-04-02
Genre: Medical
ISBN: 9780340552698

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This comprehensive work deals with the major health problem of high lipid levels in blood, a cause of serious heart and vascular disease. Formerly the province only of the chemical pathologist, cardiologists and general physicians are now offering treatment as new 'lipid-lowering' drugs become available. The area is also of considerable interest to public health physicians as changes in lifestyle (such as dietary and smoking habits) have significant effects on lipid levels. A prestigious team of contributors covers all aspects of the topic, from molecular biology to practical dietary management to help reduce lipid levels.

Plasma Lipoproteins

Plasma Lipoproteins
Author: Antonio M. Gotto
Publisher: Elsevier Publishing Company
Total Pages: 432
Release: 1987
Genre: Medical
ISBN:

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In this rapidly evolving field of research, an enormous amount of new knowledge of lipoprotein structure, function and metabolism has emerged. The 1985 Nobel Prize-winning pioneering work of Brown and Goldstein on the LDL receptor has had a profound impact on developments in the field. This work is one of the many subjects reviewed in detail in this book. The volume begins with chapters on structure, then proceeds to analysis of lipid and lipoprotein dynamics, metabolism, function, genetics, and molecular biology. Lipoprotein genetics in molecular biology, the role of lipoprotein receptors, and Lp(a) - a topic underrepresented in volumes on lipoproteins, are another three such topics in an impressive volume. This work will mainly be of interest to researchers interested in lipid and lipoprotein structure and metabolism, but will also be of great value to clinical medicine and biology in general.

Lipoproteins

Lipoproteins
Author: Gerhard Kostner
Publisher: BoD – Books on Demand
Total Pages: 778
Release: 2012-10-03
Genre: Science
ISBN: 9535107739

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By typing into databases such as Medline or PubMed the word lipoprotein one gets more than 100.000 hits that highlight the common interest in this topic. It is actually impossible to cover all aspects of lipoprotein structure, function, metabolism and pathophysiology in one issue like the present volume, but attempts have been made to concentrate on topics that are in focus of current lipoprotein research. These topics have been divided into 10 sections. This volume will help new investigators in the field to get acquainted with the general topic of lipoprotein research and will guide scientists interested in this area to emerging new fields.

Lipoproteins and Atherosclerosis

Lipoproteins and Atherosclerosis
Author: Claude L. Malmendier
Publisher: Springer Science & Business Media
Total Pages: 248
Release: 2012-12-06
Genre: Science
ISBN: 146841268X

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Atherosclerosis which accounts in Western Europe for more than 40 % of deaths, is a generalized disease that develops slowly and is symptomless until lesions have become sufficiently severe to cause myocardial or cerebral infarction. Research on specific and precocious markers of atherosclerosis and the development of non invasive techniques for their early detection represent major challenges in biomedical field. We hope that this volume of edited papers, a consequence of the third international colloquium on atherosclerosis, conducted at the University of Brussels, Belgium through the support of the "Fondation de Recherche sur l' AtherosclE,rose" will contribute to this goal. Among the topics discussed the major ones were the mechanism of action of lipolytic enzymes, the deficiency or dysregulation of cellular receptors, the genetic deficiencies of apolipoproteins, and the panoply of external factors as diet, physical exercise, drugs, which mOdify the lipoprotein metabolism. Special interest was also devoted to potent techniques as kinetic analysis of metabolic tracers and use of monoclonal antibodies. Their contribution to the detection and treatment of atherosclerosis will be obviously essential in the future.

Lipoproteins in Diabetes Mellitus

Lipoproteins in Diabetes Mellitus
Author: Alicia J. Jenkins
Publisher: Springer Science & Business Media
Total Pages: 468
Release: 2014-01-08
Genre: Medical
ISBN: 1461475546

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Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.

High Density Lipoproteins

High Density Lipoproteins
Author: Arnold von Eckardstein
Publisher: Springer
Total Pages: 0
Release: 2015-01-13
Genre: Medical
ISBN: 9783319096643

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In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.

Lipid Metabolism and Health

Lipid Metabolism and Health
Author: Robert J. Moffatt
Publisher: CRC Press
Total Pages: 377
Release: 2005-12-15
Genre: Health & Fitness
ISBN: 1420038427

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That a relation exists between lipids/lipoproteins and coronary artery disease is no longer an arguable point. However, the complexities associated with this relationship, and the number of factors that can impact and alter circumstances and clinical status, are many and diverse. Consequently, this relationship continues to receive a great deal of

Diet and Health

Diet and Health
Author: National Research Council
Publisher: National Academies Press
Total Pages: 765
Release: 1989-01-01
Genre: Medical
ISBN: 0309039940

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Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.