Different approaches of understanding Materia Medica are explained in Homoeopathy. Keynote prescription is one form of approach which author have found good results and shared in her book. Beginners, especially the students as well as the practitioners have lot of confusion on how to practice with the help of Materia Medica. It is not easy to memorize each and every symptom of medicines. Repertory is also an aid in finding the correct similar remedy. But for final selection of remedy we depend on Materia Medica. Case taking is an art and Homoeopathic case taking considers the whole diseased individual primarily and then only the disease is considered. Here the mental generals, physical generals and physical particulars are given prime importance. Complete case taking can lead to the prescription of a constitutional or a perfect similimum. But when there is lack of symptoms or when there is the need of rapid prescription, that time keynote prescription is very useful. She had learnt from her Father, a renowned Homoeopath, which is shared in her book. Both common and rare medicines are included in this book. This small step of compilation is her personal experiences based on different Materia Medica text books. Hope this experience of sharing will be a candlelight which can light thousands of candles-----who love Homoeopathy.