Isotope Effects

Isotope Effects
Author: Max Wolfsberg
Publisher: Springer Science & Business Media
Total Pages: 477
Release: 2009-12-15
Genre: Science
ISBN: 9048122651

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As the title suggests, Isotope Effects in the Chemical, Geological and Bio Sciences deals with differences in the properties of isotopically substituted molecules, such as differences in the chemical and physical properties of water and the heavy waters. Since the various fields in which isotope effects are applied do not only share fundamental principles but also experimental techniques, this book includes a discussion of experimental apparatus and experimental techniques. Isotope Effects in the Chemical, Geological and Bio Sciences is an educational monograph addressed to graduate students and others undertaking isotope effect research. The fundamental principles needed to understand isotope effects are presented in appropriate detail. While it is true that these principles are more familiar to students of physical chemistry and some background in physical chemistry is recommended, the text provides enough detail to make the book an asset to students in organic and biochemistry, and geochemistry.

Enzyme Mechanism from Isotope Effects

Enzyme Mechanism from Isotope Effects
Author: Paul F. Cook
Publisher: CRC Press
Total Pages: 656
Release: 1991-09-20
Genre: Medical
ISBN: 9780849353123

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Isotope effects have become one of the most powerful tools available to the enzymologist for probing enzymic mechanisms. Enzyme Mechanism from Isotope Effects presents the basic theory underlying isotope effects, including the latest findings on proton tunneling and coupled atomic notions. Specific theoretical applications are emphasized in regard to the types of information that can be obtained using isotope effects. The book also examines recent theoretical treatments of the product dependence of deuterium isotope effects, multiple isotope effects and isotope effects on intermediate partitioning. Other topics include a complete discussion of methods for measuring isotope effects, including a detailed description of the use of the isotope ratio mass spectrometer to obtain isotope effects, and a review of the literature regarding mechanistic information obtained from isotope effects for individual classes of enzyme-catalyzed reactions. Enzyme Mechanism from Isotope Effects is an excellent reference source for investigators using isotope effects in their research. The book is also valuable for reference libraries and instructors teaching courses in enzyme mechanism.

Isotope Effects In Chemistry and Biology

Isotope Effects In Chemistry and Biology
Author: Amnon Kohen
Publisher: CRC Press
Total Pages: 1092
Release: 2005-11-01
Genre: Medical
ISBN: 1420028022

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The field of isotope effects has expanded exponentially in the last decade, and researchers are finding isotopes increasingly useful in their studies. Bringing literature on the subject up to date, Isotope Effects in Chemistry and Biology covers current principles, methods, and a broad range of applications of isotope effects in the physical, biolo

Isotope Effects in Gas-phase Chemistry

Isotope Effects in Gas-phase Chemistry
Author: Jack A. Kaye
Publisher:
Total Pages: 456
Release: 1992
Genre: Language Arts & Disciplines
ISBN:

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Focuses on measurements and calculations of isotope effects in chemical reactions and photodissociation. Covers a variety of processes, ranging from the very simple (atom-diatom reactions) to the complex (multiligand coordination compounds) and includes both neutral and ionic species. Examines a variety of applications, including those to astrophysical, planetary, and atmospheric science. Both light- and heavy-atom isotope effects are covered.

Isotope Effects on Reaction Rates

Isotope Effects on Reaction Rates
Author: Lars C. S. Melander
Publisher:
Total Pages: 200
Release: 1960
Genre: Chemical kinetics
ISBN:

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Measurement and Analysis of Kinetic Isotope Effects

Measurement and Analysis of Kinetic Isotope Effects
Author:
Publisher: Academic Press
Total Pages: 634
Release: 2017-09-12
Genre: Medical
ISBN: 0128122749

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Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions. Written by pioneers of modern isotope effect research Is the only collection of modern kinetic isotope effect methods currently available

Magnetic Isotope Effect in Radical Reactions

Magnetic Isotope Effect in Radical Reactions
Author: Kev M. Salikhov
Publisher: Springer Science & Business Media
Total Pages: 162
Release: 1996-08-02
Genre: Science
ISBN: 9783211827840

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In the last two decades it was demonstrated that, in addition to masses and charges, magnetic moments of nuclei are able to influence remarkably chemical reactions. This book presents the physical background (both theoretical and experimental) of the magnetic isotope effects in radical reactions in solutions. Special attention has been paid to the quantitative interpretation of the available experimental data. This book will be useful for physicists, chemists and biologists employing the isotope effect in their investigations as well as for those involved in isotope separation and isotope enrichment projects. Additionally, the magnetic isotope effect appears to be important in geochemistry and cosmochemistry. The book can be recommended for postgraduates and senior undergraduate students.

Separation of Isotopes of Biogenic Elements in Two-phase Systems

Separation of Isotopes of Biogenic Elements in Two-phase Systems
Author: Boris Mikhailovich Andreev
Publisher: Elsevier
Total Pages: 317
Release: 2006-12-01
Genre: Science
ISBN: 0080468098

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Separation of Isotopes of Biogenic Elements provides a detailed overview of this area of research covering all aspects from the value of isotope effects to their practical use (equilibrium single-stage isotope effect - kinetics and mass transfer – multiplication of the single-stage isotope separation factor - technological peculiarity of processes) with the purpose of extraction from the natural mixture of the enriched and highly concentrated isotopes. In contrast to traditional books on the theory of isotope separation, the theoretical part of the book describes separation in two-phase processes in counter-flow columns. The experimental part of the book presents systematic analysis of specialists in the field of isotope separation in counter-flow columns. This book will be of interest to scientists, engineers and technical workers engaged in isotope separation processes and isotope application in nuclear physics, medicine, agro-chemistry, biology and other areas. This book may also be used in teaching theory and practical aspects in courses on physical chemistry and Isotope separation of light elements by physicochemical methods. * summarises current state of isotope research, especially biogenic elements* covering all aspects from the value of isotope effects to their practical use* of interest to scientists, engineers and technical workers engaged in isotope separation processes and isotope application

Heavy Atom Isotope Effects

Heavy Atom Isotope Effects
Author: E. Buncel
Publisher:
Total Pages: 368
Release: 1992
Genre: Chemical kinetics
ISBN:

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