Investigation Of The Factors Affecting The Separation Of Enantiomers Using Beta Cyclodextrin Mobile Phases In High Performance Liquid Chromatography
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Author | : Edward A. Mularz |
Publisher | : |
Total Pages | : 184 |
Release | : 1988 |
Genre | : Cyclodextrins in pharmaceutical technology |
ISBN | : |
Download Investigation of the Factors Affecting the Separation of Enantiomers Using Beta-cyclodextrin Mobile Phases in High Performance Liquid Chromatography Book in PDF, Epub and Kindle
Author | : w Lough |
Publisher | : Springer Science & Business Media |
Total Pages | : 278 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 940090861X |
Download Chiral Liquid Chromatography Book in PDF, Epub and Kindle
While working as a chromatographer in the pharmaceutical industry, it became apparent to the editor that there was a pressing need for a comprehensive reference text for analysts working on the resolution of enantiomers by liquid chromatography (LC). This need arises from the fact that, whereas previously it was very difficult to determine enantiomers by direct means, there is now a wide choice of direct LC methods. At the same time, regulatory authorities have been changing their attitudes towards the administration of pharmaceuticals as racemates, partly because it is now possible to study the individual enantiomers. Clearly this abundance of new information needs to be rationalized. More importantly, the chiral LC systems which are commercially available or readily accessible to the practising chromatographer needed to be reviewed and, to a much greater extent than in existing reviews or books, discussed in terms of their practical application. Accordingly this book is very much orientated towards the practical aspects of these commercially available and readily accessible chiral LC systems. To this end, it is written for practising chromatographers by a team of practising, experienced chromatographers who have spent many years tackling the problems presented by resolving enantiomers by LC. The practical aspects of common chiral LC systems cannot be fully understood if discussed in isolation.
Author | : Stephen Wren |
Publisher | : Springer Science & Business Media |
Total Pages | : 96 |
Release | : 2013-04-17 |
Genre | : Technology & Engineering |
ISBN | : 3322831418 |
Download The Separation of Enantiomers by Capillary Electrophoresis Book in PDF, Epub and Kindle
This book gives a comprehensive overview on the principles of physical and mathematical modelling of enantiomer separation by CE. Method development strategies are shown and cyclodextrins as a popular group of chiral selectors as well as some other selectors used as buffer additives for enantiomer separation in free solution are described.
Author | : B. Chankvetadze |
Publisher | : Elsevier Inc. Chapters |
Total Pages | : 27 |
Release | : 2013-01-08 |
Genre | : Science |
ISBN | : 0128071095 |
Download Liquid Chromatography Book in PDF, Epub and Kindle
This chapter summarizes major developments in the field of liquid chromatographic separation of enantiomers. After a short historical overview, the materials and technologies used for analytical and preparative scale separation of enantiomers in high-performance liquid chromatography, nano liquid chromatography, simulated moving-bed chromatography, and supercritical fluid chromatography are briefly discussed. In the final part, some future trends in liquid chromatographic separation of enantiomers are overviewed.
Author | : H. Schmidt-Traub |
Publisher | : John Wiley & Sons |
Total Pages | : 545 |
Release | : 2012-09-27 |
Genre | : Science |
ISBN | : 3527649301 |
Download Preparative Chromatography Book in PDF, Epub and Kindle
Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.
Author | : |
Publisher | : |
Total Pages | : 1828 |
Release | : 2000 |
Genre | : Medicine |
ISBN | : |
Download Cumulated Index Medicus Book in PDF, Epub and Kindle
Author | : San-Chun Chang |
Publisher | : |
Total Pages | : 260 |
Release | : 1992 |
Genre | : |
ISBN | : |
Download Enantiomeric Separation by High-performance Liquid Chromatography Using Cyclodextrin Stationary Phases Book in PDF, Epub and Kindle
Author | : Fumio Toda |
Publisher | : Springer Science & Business Media |
Total Pages | : 334 |
Release | : 2007-11-04 |
Genre | : Science |
ISBN | : 1402023375 |
Download Enantiomer Separation Book in PDF, Epub and Kindle
In spite of important advances in asymmetric synthesis, chiral compounds cannot all be obtained in a pure state by asymmetric synthesis. As a result, enantiomer separation remains an important technique for obtaining optically active materials. Although asymmetric synthesis is a once-only procedure, an enantiomer separation process can be repeated until the optically pure sample is obtained. This book discusses several new enantiomer separation methods using modern techniques developed by experts in the field. These methods consist mainly of the following three types: 1) Enantiomer separation by inclusion complexation with a chiral host compound 2) Enantiomer separation using biological methods 3) Enantiomer separation by HPLC chromatography using a column containing a chiral stationary phase. Separation of a racemic compound has been called “optical resolution” or simply “resolution”. Nowadays, the descriptions “enantiomer resolution” or “enantiomer separation” are also commonly used. Accordingly, “Enantiomer Separation” is used in the title of this book. The editor and all chapter contributors hope that this book is helpful for scientists and engineers working in this field.
Author | : Hassan Y. Aboul-Enein |
Publisher | : CRC Press |
Total Pages | : 521 |
Release | : 2003-06-03 |
Genre | : Science |
ISBN | : 1135530750 |
Download Chiral Separations By Liquid Chromatography And Related Technologies Book in PDF, Epub and Kindle
Unique in its systematic and detailed description of the various types, structures, and properties of chiral stationary phases (CSPs) and their preparation, application, and future scope, this volume highlights an assortment of liquid chromatographic approaches, including sub- and super-critical fluid chromatography, capillary electrochromatography
Author | : Wilfried A. König |
Publisher | : |
Total Pages | : 184 |
Release | : 1992 |
Genre | : Science |
ISBN | : |
Download Gas Chromatographic Enantiomer Separation with Modified Cyclodextrins Book in PDF, Epub and Kindle