Today, the world mission has unprecedentedly become a task of every national churches and believers on earth. Missionaries are being sent out from every nations to every nations! Strategists have previously noticed that Africa, along with East Asia, would emerge as the key fulcrum for world missions in the 21st Century. 2010 Lausanne Congress held in South Africa proved that to be true. Along this path, Evangelical Alliance for Preacher Training/Commission (EAPTC) opened their missions training schools in Kenya and South Korea, using this book as their training text. It was through the efforts of those missionary trainees that their work expanded into over 200 new church plants in 11 countries today. This book was put together mainly for Two-Thirds World missionary candidates who often find themselves limited with sound missions training opportunities around, while the lessons in this manual apply to all who are mission-interested. Going as a missionary or sending a missionary without proper training is quite reckless. The principles of cross-cultural mission presented in 11 chapters of this book are field-tested nuggets that can certainly equip anyone aspiring for missionary work. The training has been scientifically validated effective through research and used in Africa, Asia, Americas and Oceania. This manual is also available in French, Spanish, Portuguese and Amharic.