Innovative Technologies and Clinical Applications for Invasive and Non-Invasive Neuromodulation: From the Workbench to the Bedside

Innovative Technologies and Clinical Applications for Invasive and Non-Invasive Neuromodulation: From the Workbench to the Bedside
Author: Matteo Bologna
Publisher: Frontiers Media SA
Total Pages: 149
Release: 2020-02-13
Genre:
ISBN: 2889634698

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The possibility of harvesting the power of electric and magnetic impulses in the human body, commonly referred to as “neuromodulation,” is one of the most recent and promising developments of the modern science. Since the late ´60s, multiple invasive and non-invasive technologies have been developed and tested in experimental and clinical settings with the final aim of modulating the function of the central and peripheral nervous system. Clinical applications include, but are not limited to, common neurological disorders such as Parkinson’s disease and other movement disorders. The bulk of evidence supporting the clinical efficacy of various invasive and non-invasive approaches for neuromodulation has progressively led scientific societies, patients’ associations, and regulatory entities to acknowledge the critical role played by neuromodulation in the therapeutic algorithms of a wide range of neurological disorders. As a result, new technologies have been recently introduced into the market or are currently under validation. Their potential implementation into innovative protocols for neuromodulation demands a critical revision of what are the unmet needs for neuromodulation in movement disorders.

Non-Invasive Neuromodulation of the Central Nervous System

Non-Invasive Neuromodulation of the Central Nervous System
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Total Pages: 103
Release: 2015-11-02
Genre: Medical
ISBN: 0309376211

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Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and non-therapeutic applications of non-invasive neuromodulation will continue to expand in coming years, particularly for indications where treatments are currently insufficient, such as drug-resistant depression. Given the growing interest in non-invasive neuromodulation technologies, the Institute of Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop, inviting a range of stakeholders - including developers of devices and new technologies, researchers, clinicians, ethicists, regulators, and payers - to explore the opportunities, challenges, and ethical questions surrounding the development, regulation, and reimbursement of these devices for the treatment of nervous system disorders as well as for non-therapeutic uses, including cognitive and functional enhancement. This report highlights the presentation and discussion of the workshop.

Textbook of Neuromodulation

Textbook of Neuromodulation
Author: Helena Knotkova
Publisher: Springer
Total Pages: 284
Release: 2014-11-15
Genre: Medical
ISBN: 1493914081

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Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.

Innovative Neuromodulation

Innovative Neuromodulation
Author: Jeffrey Arle
Publisher: Academic Press
Total Pages: 342
Release: 2017-01-16
Genre: Medical
ISBN: 0128005963

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Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume. Presents a comprehensive reference on the emerging field of neuromodulation that features chapters from leading physicians and researchers in the field Provides commentary for perspectives on different technologies and interventions to heal and improve neurological deficits Contains 300 full-color pages that begin with an overview of the clinical phases involved in neuromodulation, the challenges facing therapies and intraoperative procedures, and innovative solutions for better patient care

Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices

Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices
Author: Kang-Ping Lin
Publisher: Springer
Total Pages: 439
Release: 2019-09-28
Genre: Technology & Engineering
ISBN: 9783030306359

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This book gathers the proceedings of the IV International Conference on Biomedical and Health Informatics (ICBHI 2019), held on 17-20 April, 2019, in Taipei, Taiwan. Contributions span a range of topics, including medical imaging, biosignal processing, biodata management and analytics, public and personalized health systems, mobile health applications and many more. The IV conference edition gave a special emphasis to cybersecurity issues and cutting-edge medical devices, as it is reflected in this book, which provides academics and professionals with extensive knowledge on and a timely snapshot of cutting-edge research and developments in the field of biomedical and health informatics.

Hands-on Herpetology

Hands-on Herpetology
Author: Rebecca L. Schneider
Publisher: NSTA Press
Total Pages: 163
Release: 2001
Genre: Education
ISBN: 0873551974

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This is ideal for middle and high school teachers and nature center staff who want to mix serious issues with amazing science. Plentiful, diverse, and readily available, these animals - known in science as 'herps' - are also perfect for teaching students about biology, ecology, and conservation. This highly readable resource melds rigorous science content with science research.

Comprehensive Healthcare Simulation: Neurosurgery

Comprehensive Healthcare Simulation: Neurosurgery
Author: Ali Alaraj
Publisher: Springer
Total Pages: 348
Release: 2018-05-18
Genre: Medical
ISBN: 3319755838

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This book is a practical guide for the use of simulation in neurosurgery, with chapters covering high fidelity simulation, animal models simulation, cadaveric simulation, and virtual reality simulation. Readers are introduced to the different simulation modalities and technologies and are guided on the use of simulation for a variety of learners, including medical students, residents, practicing pediatricians, and health-related professionals. Comprehensive Healthcare Simulation: Neurosurgery is written and edited by leaders in the field and includes dozens of high-quality color surgical illustrations and photographs as well as videos. This book is part of the Comprehensive Healthcare Simulation Series which provides focused volumes on the use of simulation in a single specialty or on a specific simulation topic, and emphasizing practical considerations and guidance.

Clinical Radiation Oncology

Clinical Radiation Oncology
Author: William Small, Jr.
Publisher: John Wiley & Sons
Total Pages: 940
Release: 2017-04-17
Genre: Medical
ISBN: 0470905522

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This fully updated and enhanced third edition offers a highly practical, application-based review of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Revised edition of the classic reference in radiation oncology from Dr. C.C. Wang, whose practical approach to clinical application was legendary Includes the latest developments in the field: intensity modulated radiation therapy (IMRT), image guided radiation therapy, and particle beam therapy Includes two brand new chapters Palliative Radiotherapy, and Statistics in Radiation Oncology Features a vibrant and extremely comprehensive head and neck section Provides immediately applicable treatment algorithms for each tumor

Biomedical Engineering Fundamentals

Biomedical Engineering Fundamentals
Author: Joseph D. Bronzino
Publisher: CRC Press
Total Pages: 1184
Release: 2014-12-17
Genre: Medical
ISBN: 1439825181

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Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering. More than three dozen specific topics are examined, including cardiac biomechanics, the mechanics of blood vessels, cochlear mechanics, biodegradable biomaterials, soft tissue replacements, cellular biomechanics, neural engineering, electrical stimulation for paraplegia, and visual prostheses. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.

The Alzheimer's Disease Challenge

The Alzheimer's Disease Challenge
Author: Athanasios Alexiou
Publisher: Frontiers Media SA
Total Pages: 501
Release: 2019-12-04
Genre:
ISBN: 2889631281

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Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.