"Design and development of a system can be viewed as a process of transferring and transforming data using a set of tools that form the system's development environment. Conversion of the systems engineering data into useful information is one of the prime objectives of the tools used in the process. With complex systems, the objective is further augmented with a need to represent the information in an accessible and comprehensible manner. The importance of representation is easily understood in light of the fact that the stakeholder's ability to make prompt and appropriate decisions is directly related to his understanding of the available information. Systems Modeling Language (SysML), a graphical modeling language developed by Object Management Group is one such tool used to capture and convey information about a system under development. This work proposes a methodology for integrating the models developed using SysML with virtual engineering software to create an executable, interactive, and user-centered platform for engineering systems. The framework provides an opportunity to combine the benefits offered by both model-based systems engineering and virtual engineering for detail design. This research demonstrates how this framework can be implemented using a biotech fermentor to illustrate the coupling of information between SysML and virtual engineering"--Abstract, leaf iii