This pedagogically innovative book is the only law school casebook focused on human rights advocacy in the United States. It illuminates a range of both emerging challenges and persistent theoretical and doctrinal issues while equipping students to thoughtfully engage human rights law and strategies in their own practice of law. Readings and case studies expose students to the history, tactics, and critiques of the U.S. human rights movement as well as the legal and practical challenges of human rights implementation in the United States. Skills exercises introduce practice-oriented approaches to integrating human rights in U.S. based advocacy, including through engagement with international treaty bodies, regional mechanisms, U.S. courts, and policymakers. Additionally, the appendices provide the text of relevant human rights treaties. Appropriate for both introductory and advanced seminars, as well as clinical and other experiential offerings, the materials engage students on a remarkable range of human rights issues, including climate change, reproductive justice, immigration, the rights of Indigenous peoples, racially discriminatory policing, and the human right to housing. Chapters also explore fundamental issues of federalism, sovereignty, judicial review, and legal ethics.