How We Live and Why We Die: The Secret Lives of Cells

How We Live and Why We Die: The Secret Lives of Cells
Author: Lewis Wolpert
Publisher: W. W. Norton & Company
Total Pages: 169
Release: 2011-01-24
Genre: Science
ISBN: 039329272X

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Acclaimed biologist Lewis Wolpert eloquently narrates the basics of human life through the lens of its smallest component: the cell. Everything about our existence— imagination and reproduction, birth and death—is governed by our cells. They are the basis of all life in the universe, from the tiniest of bacteria to the most complex of animals. Genes in developing embryos determine the makeup of individuals, and the rapid firing between nerve cells creates the spirit of who we are. When we age, our cells cannot repair the damage they have undergone; when we get ill, it is because cells are so damaged they stop working and die. In the tradition of Lewis Thomas’s science classic The Lives of a Cell, Wolpert, an internationally acclaimed embryologist, draws on the recent discoveries of genetics to demonstrate how human life derives from a single cell and then grows into a body: an incredibly complex society made up of billions of cells. Wolpert sensitively examines the science behind often controversial research topics that are much discussed by rarely understood—stem cell research, cloning, DNA, and mutating cancer cells—all the while illuminating how the intricacies of cellular behavior bear directly on human behavior. Wolpert isn’t afraid to tackle the tough questions, including how and why single cells evolved into complex organisms and, first and foremost, what gave rise to the original cell, the origin of all life. Lively and passionate, How We Live and Why We Die is both an accessible guide to understanding the human body and a deeply reverent meditation on life itself.

The Immortal Life of Henrietta Lacks

The Immortal Life of Henrietta Lacks
Author: Rebecca Skloot
Publisher: Crown
Total Pages: 386
Release: 2010-02-02
Genre: Science
ISBN: 0307589382

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#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

The Lives of a Cell

The Lives of a Cell
Author: Lewis Thomas
Publisher: Penguin
Total Pages: 162
Release: 1978-02-23
Genre: Science
ISBN: 1101667052

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Elegant, suggestive, and clarifying, Lewis Thomas's profoundly humane vision explores the world around us and examines the complex interdependence of all things. Extending beyond the usual limitations of biological science and into a vast and wondrous world of hidden relationships, this provocative book explores in personal, poetic essays to topics such as computers, germs, language, music, death, insects, and medicine. Lewis Thomas writes, "Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us."

Life Itself

Life Itself
Author: Boyce Rensberger
Publisher: Oxford University Press, USA
Total Pages: 314
Release: 1996
Genre: Science
ISBN:

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In Amazing Life, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. The hottest topics in biomedical research are covered.

The Secret Life of Germs

The Secret Life of Germs
Author: Philip M. Tierno
Publisher: Simon and Schuster
Total Pages: 324
Release: 2004-01-06
Genre: Health & Fitness
ISBN: 9780743421881

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Traces the history of germs, discussing how germs have been viewed and treated throughout time and explains why germs now pose an even greater risk to mankind than ever before.

The Telomere Effect

The Telomere Effect
Author: Dr. Elizabeth Blackburn
Publisher: Grand Central Publishing
Total Pages: 328
Release: 2017-01-03
Genre: Health & Fitness
ISBN: 1455587966

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The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

Naming Infinity

Naming Infinity
Author: Loren Graham
Publisher: Harvard University Press
Total Pages: 252
Release: 2009-03-31
Genre: History
ISBN: 0674032934

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In 1913, Russian imperial marines stormed an Orthodox monastery at Mt. Athos, Greece, to haul off monks engaged in a dangerously heretical practice known as Name Worshipping. Exiled to remote Russian outposts, the monks and their mystical movement went underground. Ultimately, they came across Russian intellectuals who embraced Name Worshipping—and who would achieve one of the biggest mathematical breakthroughs of the twentieth century, going beyond recent French achievements. Loren Graham and Jean-Michel Kantor take us on an exciting mathematical mystery tour as they unravel a bizarre tale of political struggles, psychological crises, sexual complexities, and ethical dilemmas. At the core of this book is the contest between French and Russian mathematicians who sought new answers to one of the oldest puzzles in math: the nature of infinity. The French school chased rationalist solutions. The Russian mathematicians, notably Dmitri Egorov and Nikolai Luzin—who founded the famous Moscow School of Mathematics—were inspired by mystical insights attained during Name Worshipping. Their religious practice appears to have opened to them visions into the infinite—and led to the founding of descriptive set theory. The men and women of the leading French and Russian mathematical schools are central characters in this absorbing tale that could not be told until now. Naming Infinity is a poignant human interest story that raises provocative questions about science and religion, intuition and creativity.

Cuckoo

Cuckoo
Author: Nick Davies
Publisher: Bloomsbury Publishing USA
Total Pages: 374
Release: 2015-04-07
Genre: Nature
ISBN: 1620409534

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A gifted biologist's careful and beguiling study of why cuckoos have got away with tricking other birds into hatching and raising their young for thousands of years. The familiar call of the common cuckoo, “cuck-oo,” has been a harbinger of spring ever since our ancestors walked out of Africa many thousands of years ago. However, for naturalist and scientist Nick Davies, the call is an invitation to solve an enduring puzzle: how does the cuckoo get away with laying its eggs in the nests of other birds and tricking them into raising young cuckoos rather than their own offspring? Early observers who noticed a little warbler feeding a monstrously large cuckoo chick concluded the cuckoo's lack of parental care was the result of faulty design by the Creator, and that the hosts chose to help the poor cuckoo. These quaint views of bad design and benevolence were banished after Charles Darwin proposed that the cuckoo tricks the hosts in an evolutionary battle, where hosts evolve better defenses against cuckoos and cuckoos, in turn, evolve better trickery to outwit the hosts. For the last three decades, Davies has employed observation and field experiments to unravel the details of this evolutionary “arms race” between cuckoos and their hosts. Like a detective, Davies and his colleagues studied adult cuckoo behavior, cuckoo egg markings, and cuckoo chick begging calls to discover exactly how cuckoos trick their hosts. For birding and evolution aficionados, The Cuckoo is a lyrical and scientifically satisfying exploration of one of nature's most astonishing and beautiful adaptations.

I Contain Multitudes

I Contain Multitudes
Author: Ed Yong
Publisher: HarperCollins
Total Pages: 285
Release: 2016-08-09
Genre: Science
ISBN: 0062368621

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New York Times Bestseller New York Times Notable Book of 2016 • NPR Great Read of 2016 • Named a Best Book of 2016 by The Economist, Smithsonian, NPR's Science Friday, MPR, Minnesota Star Tribune, Kirkus Reviews, Publishers Weekly, The Guardian, Times (London) From Pulitzer Prize winner Ed Yong, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since Darwin—a “microbe’s-eye view” of the world that reveals a marvelous, radically reconceived picture of life on earth. Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Pulitzer Prize-winning author Ed Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squid with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. It will change both our view of nature and our sense of where we belong in it.

You're Looking Very Well

You're Looking Very Well
Author: Lewis Wolpert
Publisher: Faber & Faber
Total Pages: 250
Release: 2012
Genre: Aging
ISBN: 9780571250653

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We now live longer today than at any time in history. In the UK, more people are aged over sixty-five than under sixteen and by 2050, over a third of the developed world will be over sixty. How should we deal with this phenomenon? What are the scientific reasons for ageing? And can - or should - we prevent it?Lewis Wolpert, distinguished biologist and octogenarian, explores the scientific background and the implications of our ageing population. In this engaging investigation, he tackles every aspect of the subject from ageism to euthanasia to anti-ageing cream and, through it all, tries to better understand his own ageing. Witty, frank and often inspiring, Lewis Wolpert is the perfect guide to looking very well.