Practice of High Performance Liquid Chromatography

Practice of High Performance Liquid Chromatography
Author: Heinz Engelhardt
Publisher: Springer Science & Business Media
Total Pages: 468
Release: 2012-12-06
Genre: Science
ISBN: 3642692257

Download Practice of High Performance Liquid Chromatography Book in PDF, Epub and Kindle

During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).

New Developments in Clinical Instrumentation

New Developments in Clinical Instrumentation
Author: Leroy Hersh
Publisher: CRC Press
Total Pages: 294
Release: 2018-01-18
Genre: Science
ISBN: 1351091875

Download New Developments in Clinical Instrumentation Book in PDF, Epub and Kindle

This book has information regarding the new developments in clinical instrumentation, focusing on fluorometers and densitometers, explaining the principles, the use of high performance liquid chromatography in clinical laboratories. Automated Microbiology; dabbling into detection, light scanning and analysis of particles. Amore recent aspect of automation has been, made possible by the advent of the microprocessor orcomputer-on-a-chip. The development of miniature, inexpensive micro-computers has resulted in the automation for relatively sophisticated processes. The two aspects of automation are represented in this monograph. The automated control of physical processes, and automation of the information processing. There are elements of both aspects of automation in this book. The areas discussed do emphasize more or less strongly either tight automated control of physical processes or automation of information processing. They all represent the attempt of medical technology to yield more precise, accurate, less expensive and faster to acid in the clinical diagnosis.

High Performance Liquid Chromatography

High Performance Liquid Chromatography
Author: Omar Al Sayed Omar
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 501
Release: 2022-02-21
Genre: Science
ISBN: 3110528959

Download High Performance Liquid Chromatography Book in PDF, Epub and Kindle

During the past decade, modern high-performance liquid chromatography (HPLC) utilization has expanded greatly, especially in the quality control of pharmaceutical products in drug quality control laboratories. This book provides an extensive collection of technical information about HPLC-Columns (physicochemical properties and chromatographic characteristics), from various manufacturers, and helps analysts to decide on the ideal approach for their analysis according to the requirements of drug manufacturers specifi cations and the desired Pharmacopeia. In addition, the authors give practical advice on how to prepare mobile phases, choose a suitable detector, and set up an HPLC analysis. This book is comprehensive for the average professional or technician who plans to work with modern HPLC. This book is useful for most Drug Quality Control Laboratories where modern HPLC is utilized. Following a hands-on approach, the book gives key insights into the pharmaceutical applications of HPLC and the latest requirements of the major regulatory agencies such as ICH, FDA, or USP.

Chromatographic Methods in Clinical Chemistry and Toxicology

Chromatographic Methods in Clinical Chemistry and Toxicology
Author: Roger Bertholf
Publisher: John Wiley & Sons
Total Pages: 308
Release: 2007-01-30
Genre: Science
ISBN: 0470023104

Download Chromatographic Methods in Clinical Chemistry and Toxicology Book in PDF, Epub and Kindle

This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications. Chromatography has a vast array of clinical applications, and though the chromatographic methods were first introduced decades ago, new applications of this technology are being used to explore previously inaccessible frontiers in clinical diagnostics and toxicological testing. An up-to-date book devoted to clinical and toxicological applications of chromatographic methods will serve as an instructional and reference text, useful to students, laboratory technicians, and researchers.

High Performance Liquid Chromatography

High Performance Liquid Chromatography
Author: Sandie Lindsay
Publisher: John Wiley & Sons
Total Pages: 370
Release: 1992-07-27
Genre: Science
ISBN: 0471931152

Download High Performance Liquid Chromatography Book in PDF, Epub and Kindle

High performance liquid chromatography is the most powerful of all the chromatographic techniques, often achieving separations and analyses that would be difficult or impossible with other forms of chromatography. This study and training text examines the concepts and techniques used in this field. A selection of literature available from equipment manufacturers is included along with a brief review of some more specialized topics.

Practice of High Performance Liquid Chromatography

Practice of High Performance Liquid Chromatography
Author: Heinz Engelhardt
Publisher: Springer
Total Pages: 464
Release: 2011-12-27
Genre: Science
ISBN: 9783642692260

Download Practice of High Performance Liquid Chromatography Book in PDF, Epub and Kindle

During its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).

HPLC in the Pharmaceutical Industry

HPLC in the Pharmaceutical Industry
Author: Godwin W. Fong
Publisher: CRC Press
Total Pages: 332
Release: 1991-03-14
Genre: Science
ISBN: 9780824784997

Download HPLC in the Pharmaceutical Industry Book in PDF, Epub and Kindle

A practical guide for chemists in the pharmaceutical industry to making automated analyses of drugs that will meet the standards of regulatory agencies. Reviews the standard techniques of high-performance liquid chromatography, specialized detection methods, automation in pharmaceutical analysis, an

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography
Author: Steven H.Y. Wong
Publisher: Routledge
Total Pages: 521
Release: 2017-09-19
Genre: Medical
ISBN: 135140847X

Download Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography Book in PDF, Epub and Kindle

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.