Cytochromes

Cytochromes
Author: David F.V. Lewis
Publisher: Taylor & Francis
Total Pages: 344
Release: 2003-09
Genre: Science
ISBN: 1135743282

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Guide to Cytochromes P450

Guide to Cytochromes P450
Author: David F. V. Lewis
Publisher: CRC Press
Total Pages: 223
Release: 2001-04-12
Genre: Medical
ISBN: 1420023047

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Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate level or in particular within the pharmaceutical industry. A Guide to Cytochrome P450 Structure and Function acts as an adjunct to the previous book Cytochromes P450: Structure, Function and Mechanism. It reviews the current status of the P450 field in terms of our present knowledge and understanding of the enzymes structure and function, including their multiplicity of forms, diversity of substrates, and selectivity. This is brought together with the latest research topics, including pharmacogenetics, regulation, human DMEs, toxicity screening and molecule modeling, to provide a fast-track approach for those new to the field.

Guide to Cytochromes

Guide to Cytochromes
Author: David F.V. Lewis
Publisher: CRC Press
Total Pages: 344
Release: 1996-07-03
Genre: Science
ISBN: 0748404430

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This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.

Guide to Cytochromes P450

Guide to Cytochromes P450
Author: David F.V. Lewis
Publisher: CRC Press
Total Pages: 344
Release: 1996-07-03
Genre: Science
ISBN: 1482272776

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This book covers the relevant aspects of cytochromes P450 for understanding their structure, function and mechanisms of action, such as physicochemical characterization methods, redox interactions, evolution and genetics, experimental and theoretical models, induction, inhibition and metabolism.

Guide to Cytochromes

Guide to Cytochromes
Author: David F. V. Lewis
Publisher: CRC Press
Total Pages: 252
Release: 2001-08-23
Genre: Medical
ISBN: 9780748408979

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Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate level or in particular within the pharmaceutical industry. A Guide to Cytochrome P450 Structure and Function acts as an adjunct to the previous book Cytochromes P450: Structure, Function and Mechanism. It reviews the current status of the P450 field in terms of our present knowledge and understanding of the enzymes structure and function, including their multiplicity of forms, diversity of substrates, and selectivity. This is brought together with the latest research topics, including pharmacogenetics, regulation, human DMEs, toxicity screening and molecule modeling, to provide a fast-track approach for those new to the field.

Quick Guide to the Cytochrome P450 System

Quick Guide to the Cytochrome P450 System
Author: Kelly L. Cozza
Publisher:
Total Pages: 262
Release: 2002
Genre: Cytochrome P-450
ISBN: 9781585620739

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Topics covered in this volume include: an introduction to the P450 system and basic pharmacology; an introduction to P450 and to this concise guide; basic Pharmacology; metabolic variability - inhibition, induction, and pharmacogenetics; P450 Enzymes; 2D6; 3A4; 1A2; 2C9; 2C19; 2E1; guidelines; how to retrieve and review the literature.

Cytochrome P450

Cytochrome P450
Author: Paul R. Ortiz de Montellano
Publisher: Springer Science & Business Media
Total Pages: 702
Release: 2007-02-05
Genre: Medical
ISBN: 0387274472

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Cytochrome P450: Structure, Mechanism, and Biochemistry, third edition is a revision of a review that summarizes the current state of research in the field of drug metabolism. The emphasis is on structure, mechanism, biochemistry, and regulation. Coverage is interdisciplinary, ranging from bioinorganic chemistry of cytochrome P450 to its relevance in human medicine. Each chapter provides an in-depth review of a given topic, but concentrates on advances of the last 10 years.

Concise Guide to the Cytochrome P450 System

Concise Guide to the Cytochrome P450 System
Author: Kelly L. Cozza
Publisher: American Psychiatric Publishing
Total Pages: 294
Release: 2001
Genre: Medical
ISBN:

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Adverse medication reactions account for up to 7,000 deaths annually in the United States. In today's era of polypharmacy, busy clinicians - especially those who practice in medical/surgical settings - must be able to quickly find and even anticipate psychiatric drug interactions.

Cytochrome P450

Cytochrome P450
Author:
Publisher:
Total Pages: 379
Release: 2021
Genre: Cytochrome P-450
ISBN: 9781071615447

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