Discover the Global Rinderpest Action Plan (GRAP), an international strategy designed to prevent the re-emergence of rinderpest, safeguarding global livestock and ecosystems. [Author] Rinderpest is the only animal disease that has been globally eradicated. [Author] The greatest risk for rinderpest re-emergence is the release, whether intentional or unintentional, of infectious material from a Rinderpest Holding Facility (RHF) among susceptible animal populations. [Author] The re-emergence of disease would be a global animal health emergency, leading to the loss of global disease freedom and threatening livelihoods, food security, international trade and national economies. [Author] The GRAP is an international operational plan that addresses activities related to the potential re-emergence of rinderpest. [Author] The GRAP applies an emergency management cycle approach to prepare for, prevent, detect, respond to, and recover from a potential re-emergence of rinderpest, and it addresses responsibility for each stage of the cycle at the national, regional/continental, and international levels. [Author] By identifying gaps in preparedness and prioritizing risk mitigation measures, the GRAP enhances global readiness for potential rinderpest re-emergence. [Author] It builds confidence among decision-makers to eliminate remaining virus stocks and strengthens coordination across national, regional, and international levels. [Author] The GRAP's scope encompasses a wide array of stakeholders, including government officials, academics, livestock keepers, and international organizations. [Author] It aims to facilitate coordinated responses to rinderpest outbreaks and assesses readiness levels to address gaps in preparedness. [Author] The plan operates under the assumption that rinderpest virus material remains a risk and underscores the importance of swift eradication in the event of confirmed cases to maintain global rinderpest freedom. [Author]