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| Author | : Julio Collado-Vides |
| Publisher | : MIT Press |
| Total Pages | : 326 |
| Release | : 2002 |
| Genre | : Computers |
| ISBN | : 9780262532686 |
An overview of current computational approaches to metabolism and gene regulation.
| Author | : Julio Collado-Vides |
| Publisher | : |
| Total Pages | : 310 |
| Release | : 2004 |
| Genre | : Genetics |
| ISBN | : 9788180520532 |
| Author | : Joe B. Harford |
| Publisher | : John Wiley & Sons |
| Total Pages | : 372 |
| Release | : 1997-03-28 |
| Genre | : Science |
| ISBN | : 9780471142065 |
mRNA METABOLISM & POST-TRANSCRIPTIONAL GENE REGULATION Edited by Joe B. Harford and David R. Morris Gene expression is a process that begins with the transcription ofDNA to an RNA messenger (mRNA), which is then translated into aprotein. Historically, attention has been focused on the regulationof RNA synthesis (transcription); however, there is a growingrecognition of and appreciation for the importance of the manyregulatory mechanisms that take place after RNA synthesis has beencompleted. mRNA Metabolism and Post-Transcriptional Gene Regulation is thefirst comprehensive overview of the various modes of generegulation that exist post-transcriptionally. Collecting studies bysome of the top researchers in the field, this volume provides bothan up-to-date review of the complex "life" of an mRNA molecule andan introduction to current work on the diversity of mechanisms ofpost-transcriptional reactions. Topics covered include: * RNA structure * Mammalian RNA editing * RNA export from the nucleus * The fundamentals of translation initiation * Control of mRNA decay in plants * mRNA metabolism and cancer * Control of mRNA stability during herpes simplex virus infection * Regulation of mRNA expression in HIV-1 and other complexretroviruses * Nucleases * RNA localization A timely contribution to the understanding of genetic regulatorymechanisms, mRNA Metabolism and Post-Transcriptional GeneRegulation provides a basis from which potential therapeuticstrategies may be developed. This book will be of vital interest tocell and molecular biologists at all levels, from graduate studentsto senior investigators, clinical researchers, and professionals inthe pharmaceutical and biotechnology industries.
| Author | : Béatrice Clouet-d'Orval |
| Publisher | : Springer |
| Total Pages | : 276 |
| Release | : 2017-10-28 |
| Genre | : Science |
| ISBN | : 331965795X |
This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.
| Author | : Byung Hong Kim |
| Publisher | : Cambridge University Press |
| Total Pages | : 509 |
| Release | : 2019-05-16 |
| Genre | : Medical |
| ISBN | : 1107171733 |
Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 101 |
| Release | : 2002-02-07 |
| Genre | : Technology & Engineering |
| ISBN | : 0309169917 |
The science of animal nutrition has made significant advances in the past century. In looking back at the discoveries of the 20th century, we can appreciate the tremendous impact that animal nutrition has had on our lives. From the discovery of vitamins and the sweeping shift in the use of oilseeds to replace animal products as dietary protein sources for animals during the war times of the 1900s-to our integral understanding of nutrients as regulators of gene expression today-animal nutrition has been the cornerstone for scientific advances in many areas. At the milestone of their 70th year of service to the nation, the National Research Council's (NRC) Committee on Animal Nutrition (CAN) sought to gain a better understanding of the magnitude of recent discoveries and directions in animal nutrition for the new century we are embarking upon. With financial support from the NRC, the committee was able to organize and host a symposium that featured scientists from many backgrounds who were asked to share their ideas about the potential of animal nutrition to address current problems and future challenges.
| Author | : Bruce Alberts |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cytology |
| ISBN | : 9780815332183 |
| Author | : Kenneth B. Storey |
| Publisher | : John Wiley & Sons |
| Total Pages | : 640 |
| Release | : 2005-02-25 |
| Genre | : Science |
| ISBN | : 0471675571 |
Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.
| Author | : Simon Silver |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 479 |
| Release | : 2012-12-06 |
| Genre | : Science |
| ISBN | : 1461559936 |
This is the first volume on the role of metal ions in regulating genes to focus not only on toxicity effects of metals but also on the role of metal ions in normal metabolisms, in both prokaryotes and in eukaryotes. This book is a comprehensive treatment of the role of metal ions in gene regulation, and it will be of great utility for those doing basic biological and biomedical research.
| Author | : Byung Hong Kim |
| Publisher | : Cambridge University Press |
| Total Pages | : 934 |
| Release | : 2008-02-21 |
| Genre | : Science |
| ISBN | : 113946762X |
Recent determination of genome sequences for a wide range of bacteria has made in-depth knowledge of prokaryotic metabolic function essential in order to give biochemical, physiological, and ecological meaning to the genomic information. Clearly describing the important metabolic processes that occur in prokaryotes under different conditions and in different environments, this advanced text provides an overview of the key cellular processes that determine bacterial roles in the environment, biotechnology, and human health. Prokaryotic structure is described as well as the means by which nutrients are transported into cells across membranes. Glucose metabolism through glycolysis and the TCA cycle are discussed, as well as other trophic variations found in prokaryotes, including the use of organic compounds, anaerobic fermentation, anaerobic respiratory processes, and photosynthesis. The regulation of metabolism through control of gene expression and control of the activity of enzymes is also covered, as well as survival mechanisms used under starvation conditions.
