Fungal Pathogenesis

Fungal Pathogenesis
Author: Richard Calderone
Publisher: CRC Press
Total Pages: 784
Release: 2001-10-12
Genre: Science
ISBN: 9780824705688

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Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution outlines rapid identification of major mycoses utilizing antigen capture and molecular assays details signaling and phenotypic switching discusses the value of genomics in validation highlights state-of-the-art molecular methodologies to study disease-causing organisms describes available and potential antifungal drug targets and drug development considers predicting the consequences of drug resistance on patient management presents topical observations on strain typing and variation and more! Containing research into the virulence, immunity, diagnosis, and therapy of most common fungal infections, Fungal Pathogenesis is an unparalleled reference for microbiologists, virologists, pathologists and phytopathologists, infectious disease specialists, molecular and cell biologists, biochemists, immunologists, medical mycologists, biotechnologists, and geneticists, and an exceptional text for upper-level undergraduate, graduate, and medical school students in these disciplines.

Oxford Textbook of Medical Mycology

Oxford Textbook of Medical Mycology
Author: Christopher C. Kibbler
Publisher: Oxford University Press
Total Pages: 401
Release: 2017-12-14
Genre: Medical
ISBN: 0198755384

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The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.

Fungal Pathogenesis in Plants and Crops

Fungal Pathogenesis in Plants and Crops
Author: P. Vidhyasekaran
Publisher: CRC Press
Total Pages: 536
Release: 2007-08-09
Genre: Science
ISBN: 1420021036

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Dramatic progress in molecular biology and genetic engineering has recently produced an unparalleled wealth of information on the mechanisms of plant and pathogen interactions at the cellular and molecular levels. Completely revised and expanded, Fungal Pathogenesis in Plants and Crops: Molecular Biology and Host Defense Mechanisms, Second Edition

Fungal Pathogenesis in Humans

Fungal Pathogenesis in Humans
Author: Fernando Leal
Publisher: MDPI
Total Pages: 232
Release: 2019-05-27
Genre: Science
ISBN: 3038979007

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Dear Colleagues, Cancer survival rates and successful organ transplantation in patients continues to increase due to improvements in early diagnosis and treatments. Since immuno-suppressive therapies are frequently used, the mortality rate due to secondary infections has become an ever-increasing problem. Opportunistic fungal infections are probably the deadliest threat to these patients due to their difficult early diagnosis, the limited effect of antifungal drugs and the appearance of resistances. In recent years, a considerable effort has been devoted to investigating the role of many virulence traits in the pathogenic outcome of fungal infections. New virulence factors (hypoxia adaptation, CO2 sensing, pH regulation, micronutrient acquisition, secondary metabolites, immunity regulators, etc.) have been reported and their molecular mechanisms of action are being thoroughly investigated. The recent application of gene-editing technologies such as CRISPr-Cas9, has opened a whole new window to the discovery of new fungal virulence factors. Accurate fungal genotyping, Next Generation Sequencing and RNAseq approaches will undoubtedly provide new clues to interpret the plethora of molecular interactions controlling these complex systems. Unraveling their intimate regulatory details will provide insights for a more target-focused search or a rational design of more specific antifungal agents. This Special Issue is show significant discoveries, proofs of concept of new theories or relevant observations in fungal pathogenesis and its regulation. Dr. Fernando Leal Guest Editor

Pathogenic Fungi

Pathogenic Fungi
Author: Gioconda San-Blas
Publisher: Caister Academic Press Limited
Total Pages: 392
Release: 2004
Genre: Medical
ISBN:

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The past decade has witnessed a mushrooming of research in the area of medical mycology. San-Blas (Venezuela Institute of Scientific Investigation) and Calderone (Georgetown University) present recent work in the field. Papers on fungal dimorphism and pathogenicity focus on morphogenesis, the cell cycle, and the cell wall of human pathogens, while.

Identification of Pathogenic Fungi

Identification of Pathogenic Fungi
Author: Colin K. Campbell
Publisher: John Wiley & Sons
Total Pages: 351
Release: 2013-01-25
Genre: Medical
ISBN: 1118520076

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Since the first edition of Identification of Pathogenic Fungi, there has been incredible progress in the diagnosis, treatment and prevention of fungal diseases: new methods of diagnosis have been introduced, and new antifungal agents have been licensed for use. However, these developments have been offset by the emergence of resistance to several classes of drugs, and an increase in infections caused by fungi with innate resistance to one or more classes. Identification of Pathogenic Fungi, Second Edition, assists in the identification of over 100 of the most significant organisms of medical importance. Each chapter is arranged so that the descriptions for similar organisms may be found on adjacent pages. Differential diagnosis details are given for each organism on the basis of both colonial appearance and microscopic characteristics for the organisms described. In this fully updated second edition, a new chapter on the identification of fungi in histopathological sections and smears has been added, while colour illustrations of cultures and microscopic structures have been included, and high quality, four colour digital images are incorporated throughout.

Plant Fungal Pathogens

Plant Fungal Pathogens
Author: Melvin Dennis Bolton
Publisher: Springer Science+Business Media
Total Pages: 648
Release: 2012
Genre: Science
ISBN: 9781617795015

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Including reproducible laboratory protocols, this guide to fungal pathogens in plants has been written by expert researchers in the field and includes methods now used to study them, including techniques for model systems such as Arabidopsis thaliana.

Fungal Physiology and Immunopathogenesis

Fungal Physiology and Immunopathogenesis
Author: Marcio L. Rodrigues
Publisher: Springer Nature
Total Pages: 301
Release: 2019-09-03
Genre: Medical
ISBN: 3030302377

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This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the book’s closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.

Fungal Pathogenesis in Plants and Crops

Fungal Pathogenesis in Plants and Crops
Author: P. Vidhyasekaran
Publisher: CRC Press
Total Pages: 594
Release: 1997-07-25
Genre: Science
ISBN: 9780824700393

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From the molecular basis of host defense mechanisms and molecular events leading to the suppression of defense mechanisms by fungal pathogens to fungal infection processes, this work covers various aspects of molecular plant pathology. It includes initial contact, penetration and subsequent evasion of post-penetration defense mechanisms. It documents and illustrates up-to-date experimental results and hypotheses.