As pointed out in my last two publications, no comprehensive study has been undertaken about the American Learned Men and Women with Czechoslovak roots. The aim of this work is to correct this glaring deficiency, with the focus on immigration from the period of mass migration and beyond, irrespective whether they were born in their European ancestral homes or whether they have descended from them. Whereas in the two mentioned monographs, the emphasis has been on scholars and social and natural scientists; and men and women in medicine, applied sciences and engineering, respectively, the present compendium deals with notable Americans of Czechoslovak ancestry in arts and letters, and in education. With respect to women, although most professional fields were closed to them through much of the nineteenth century, the area of arts and letters was opened to them, as noted earlier and as this compendium authenticates.