Fluorine Chemistry Research Advances

Fluorine Chemistry Research Advances
Author: Ira V. Gardiner
Publisher: Nova Publishers
Total Pages: 336
Release: 2007
Genre: Science
ISBN: 9781600217302

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Fluorine continues to intrigue chemists who overcome the challenge of handling this remarkable halogen and work to develop varied methods for synthesising fluorine compounds. The unique properties of these materials, ranging from inert perfluorocarbons and fluoropolymers to a multitude of other fascinating fluorinated compounds, firmly established their place amidst the technological achievements of the 20th Century. Fluorine substitution in biologically active compounds has become particularly significant in recent years. This book presents new and significant research in this field.

New Fluorinated Carbons: Fundamentals and Applications

New Fluorinated Carbons: Fundamentals and Applications
Author: Olga V. Boltalina
Publisher: Academic Press
Total Pages: 444
Release: 2016-09-08
Genre: Science
ISBN: 0128035021

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New Fluorinated Carbons: Fundamentals and Applications is the second volume in Alain Tressaud’s Progress in Fluorine Science series. This volume provides an overview of cutting-edge research and emerging applications using new fluorinated carbon materials such as fullerenes, carbon nanotubes, polycyclic aromatic molecules, carbon nanofibers, and graphenes. Edited by recognized experts Olga Boltalina and Tsuyoshi Nakajima, this book includes valuable chapters on syntheses, structure analyses, and chemical and physical properties of fluorinated carbons written by leaders in each respective field. The work also explores the diverse practical applications of these functional materials—from energy storage and energy conversion devices to molecular electronics and lubricants. Features contributions by leading experts in the field Includes fundamental and current research on synthesis, chemical, and physical properties of fluorinated carbons Explores practical applications in energy, electronics, and lubricants Examines a range of new fluorinated carbon materials

Fluorine

Fluorine
Author: Alain Tressaud
Publisher: Academic Press
Total Pages: 274
Release: 2018-10-06
Genre: Science
ISBN: 0128129913

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Fluorine: A Paradoxical Element, Volume Five, deals with the link between fluorine, humanity and the environment. It is divided into three main sections, including i) The history and developmental stages of fluorinated products, ii) Awareness of its importance in our environment, and iii) Recent contributions of fluoride products in medicine, pharmacy and our daily lives. Made engaging through interesting figures and accessible language, and written by a leading expert, Professor Tressaud, the book supports the work of scientists working in materials, toxicology and environmental science. It complements the author’s edited series, Progress in Fluorine Science, covering recent advances. Describes background and contextual information regarding the history, development of understanding, and applications of this important element Explores the impacts of fluorine, both positive and negative, in the environment and biological systems Includes applied, real-world information from agencies, such as CNRS, NASA, HWS and DOH

Fluorine in Pharmaceutical and Medicinal Chemistry

Fluorine in Pharmaceutical and Medicinal Chemistry
Author: Véronique Gouverneur
Publisher: World Scientific
Total Pages: 571
Release: 2012
Genre: Medical
ISBN: 1848166346

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Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For examples, the reader will discover how fluorine has found its place as a key element improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.

Fluorine in Medicinal Chemistry and Chemical Biology

Fluorine in Medicinal Chemistry and Chemical Biology
Author: Iwao Ojima
Publisher: John Wiley & Sons
Total Pages: 640
Release: 2009-03-23
Genre: Science
ISBN: 9780470744086

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The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals
Author: Gunter Haufe
Publisher: Academic Press
Total Pages: 688
Release: 2018-09-19
Genre: Science
ISBN: 0128127341

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Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals, volume four in Alain Tressaud’s Progress in Fluorine Science series, presents a critical, multidisciplinary overview of the contributions of fluorinated products to solve important global issues in various life science fields, particularly in medicinal chemistry, molecular imaging techniques and agriculture. Edited by recognized experts, this book provides unique coverage of the wide-ranging uses and implications of fluorine and fluorinated compounds. Topics include medicinal monitoring and diagnosis, 19F MRI in medicine and in vivo cell tracking, 18F-labeled radiopharmaceuticals, brain imaging and neurology, risk assessment of reactive metabolites in drug discovery, and more. Edited by Alain Tressaud, past Chair and founder of the CNRS French Fluorine Network, each book in the collection also includes the work of highly-respected volume editors and contributors from both academia and industry who bring valuable and varied content to this active field. Covers a wide range of topics - from organic and physical chemistry, to pharmaceuticals, agrochemicals and medical diagnostics Describes major modern syntheses and unique reaction mechanisms yielding fluorine compounds in these diverse life science settings Features contributions from a wealth of global experts Acts as the fourth volume in Alain Tressaud’s Progress in Fluorine Science

Fluorine Chemistry at the Millennium

Fluorine Chemistry at the Millennium
Author: R.E. Banks
Publisher: Elsevier
Total Pages: 661
Release: 2000-12-04
Genre: Science
ISBN: 0080531792

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This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest. There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.

Advanced Fluoride-Based Materials for Energy Conversion

Advanced Fluoride-Based Materials for Energy Conversion
Author: Tsuyoshi Nakajima
Publisher: Elsevier
Total Pages: 459
Release: 2015-04-30
Genre: Technology & Engineering
ISBN: 0128007125

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Advanced Fluoride-Based Materials for Energy Conversion provides thorough and applied information on new fluorinated materials for chemical energy devices, exploring the electrochemical properties and behavior of fluorinated materials in lithium ion and sodium ion batteries, fluoropolymers in fuel cells, and fluorinated carbon in capacitors, while also exploring synthesis applications, and both safety and stability issues. As electronic devices, from cell phones to hybrid and electric vehicles, are increasingly common and prevalent in modern lives and require dependable, stable chemical energy devices with high-level functions are becoming increasingly important. As research and development in this area progresses rapidly, fluorine compounds play a critical role in this rapid progression. Fluorine, with its small size and the highest electronegativity, yields stable compounds under various conditions for utilization as electrodes, electrolytes, and membranes in energy devices. The book is an ideal reference for the chemist, researcher, technician, or academic, presenting valuable, current insights into the synthesis of fluorine compounds and fluorination reactions using fluorinating agents. Provides thorough and applied information on new fluorinated materials for chemical energy devices Describes the emerging role of stable energy devices with high-level functions and the research surrounding the technology Ideal for the chemist, research, technician, or academic seeking current insights into the synthesis of fluorine compounds and fluorination reactions using fluorinating agents

Photonic and Electronic Properties of Fluoride Materials

Photonic and Electronic Properties of Fluoride Materials
Author: Alain Tressaud
Publisher: Elsevier
Total Pages: 532
Release: 2016-03-15
Genre: Science
ISBN: 0128017953

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Photonic and Electronic Properties of Fluoride Materials: Progress in Fluorine Science, the first volume in this new Elsevier series, provides an overview of the important optical, magnetic, and non-linear properties of fluoride materials. Beginning with a brief review of relevant synthesis methods from single crystals to nanopowders, this volume offers valuable insight for inorganic chemistry and materials science researchers. Edited and written by leaders in the field, this book explores the practical aspects of working with these materials, presenting a large number of examples from inorganic fluorides in which the type of bonding occurring between fluorine and transition metals (either d- or 4f-series) give rise to peculiar properties in many fundamental and applicative domains. This one-of-a-kind resource also includes several chapters covering functional organic fluorides used in nano-electronics, in particular in liquid crystal devices, in organic light-emitting diodes, or in organic dyes for sensitized solar cells. The book describes major advances and breakthroughs achieved by the use of fluoride materials in important domains such as superconductivity, luminescence, laser properties, multiferroism, transport properties, and more recently, in fluoro-perovskite for dye-sensitized solar cells and inorganic fluoride materials for NLO, and supports future development in these varied and key areas. The book is edited by Alain Tressaud, past chair and founder of the CNRS French Fluorine Network. Each book in the collection includes the work of highly-respected volume editors and contributors from both academia and industry to bring valuable and varied content to this active field. Provides unique coverage of the physical properties of fluoride materials for chemists and material scientists Begins with a brief review of relevant synthesis methods from single crystals to nanopowders Includes valuable information about functional organic fluorides used in nano-electronics, in particular in liquid crystal devices, in organic light-emitting diodes, or in organic dyes for sensitized solar cells